Chapter 05: The Path to Gene Expression

5.TB 5.005 What did Beadle and Tatum use to generate mutations in their experimental organism?A)mustard gasB)irradiation with ultraviolet lightC)fluorescent dyesD)ethidium bromideE)Coomassie blueAns:BDifficulty:Easy5.16.TB 5.006 Beadle and Tatum's research suggested that __________.A)a gene carries the information to build lipidsB)a gene carries the information to build carbohydratesC)a gene carries the information for the construction of a particular enzymeD)a gene is made of RNAE)a gene is made of DNAAns:CDifficulty:Medium5.17.TB 5.007 What was the new name of Beadle and Tatum's hypothesis after it was discovered that some enzymes were composed of more than one polypeptide chain?A)the One Gene – One Enzyme hypothesisB)the One Gene – One Polypeptide hypothesisC)the One Polypeptide – One Enzyme hypothesisD)the One Polypeptide – One Gene hypothesisE)the One Gene – Two Gene hypothesisAns:BDifficulty:Easy5.18.TB 5.008 Why has the One Gene – One Polypeptide hypothesis had to be modified?A)It was totally wrong.B)Genes can be spliced differently to generate a variety of related polypeptides.C)Enzymes sometimes consist of more than one polypeptide, each of which is coded for by its own gene.D)Enzymes actually code for genes.E)Polypeptides code for genes.Ans:BDifficulty:Medium5.1 Karp 6e Chapter 05: The Path to Gene Expression9.TB 5.009 Which scientist is best known for his work on sickle cell anemia and proving the mechanism that causes the disease?A)Charles DarwinB)Archibald GarrodC)George BeadleD)Vernon IngramE)James WatsonAns:DDifficulty:Easy5.110.TB 5.010 What difference between sickle cell and normal hemoglobin is apparently responsible for all of the symptoms associated with sickle cell anemia?A)The difference is a valine substitution in the mutant sickle cell hemoglobin for a glutamic acid in thenormal molecule.B)The difference is a glutamic acid substitution in the mutant sickle cell hemoglobin for a valine in thenormal molecule.C)The sickle cell hemoglobin is longer.D)The sickle cell hemoglobin is shorter.E)The sickle cell hemoglobin is translated backwards.Ans:ADifficulty:Difficult5.111.TB 5.011 What is the process by which complementary RNAs are synthesized from a DNA template?A)translationB)transcriptionC)protein synthesisD)transductionE)transliteration