RNSG 1251

Genetic considerations Defective genes Transmissible inherited disorders Chromosomal anomalies Multiple gestation Large fetal size ABO incompatibility Nutritional Status Young age Three pregnancies in the previous 2 years Tobacco, alcohol, or drug use Inadequate or excessive weight gain Hematocrit value less than 33% Medical and Obstetric Disorders Polyhydramnios Poorly controlled DM Fetomaternal hemorrhage Fetal congenital anomalies (e.g. GI obstruction, CNS abnormalities) Genetic disorders Twin-twin transfusion syndrome Intrauterine Growth Restriction Maternal Causes Hypertensive disorders Pregestational diabetes Cyanotic heart diseases Autoimmune disease Restrictive pulmonary disease Multifetal gestation Malabsorptive disease/malnutrition Living at a high altitude Tobacco/substance abuse Fetal Causes Genetic disorders Teratogenic exposure Fetal infection Oligohydramnios Renal agenesis (Potter syndrome) Premature rupture of membranes Prolonged pregnancy Uteroplacental insufficiency Severe intrauterine growth restriction (IUGR) Maternal hypertensive disorder Maternal dehydration/hypovolemia Chromosomal Abnormalities Advanced maternal age Parental chromosomal rearrangements Previous pregnancy with autosomal trisomy Abnormal ultrasound findings during the current pregnancy (e.g. fetal structural anomalies, IUGR, amniotic fluid volume abnormalities) Psychosocial factors Smoking Low-birth weight infants 1