Summary NURS 6560 Final Study Guide

1. Resection of the liver and regeneration and follow up labs pp 546-548 -commonly indicated for primary and secondary malignant tumours and symptomatic benign tumours -May also but indicated in traumatic injury, infection/abscesses, and living donor transplantation -after resection, the liver function will be impaired for several wks -Regeneration starts within 24hr with hepatic cell replication and has considerable regeneration within 10 days and completed regeneration by 4-5wks. -growth consists of the formation of new lobules and expansion of residual lobules -Resection is contraindicated in cirrhosis due to the liver not being able to meet metabolic demand for regeneration of tissue. -Child-Pugh classification: based on the number of ascites, degree of encephalopathy, albumin, total bilirubin and PTT/PT levels; this predicts mortality in pts with cirrhosis after hepatic resection -Child-Pugh A and selective B pts are candidates for resection -up to 80% of the liver can