Central nervous system neurotransmitters summary

CNS DISEASE Central nervous system neurotransmitters 1. Amino acid neurotransmitters a. Excitatory- glutamate b. Inhibitory- GABA (target in CNS for anticonvulsants/benzo) 2. Amine neurotransmitters a. Catecholamines i. Dopamine controls mvmt and emotions ii. Norepi affects HR, BP, bladder iii. epinephrine BP, HR, attention b. Serotonin c. Histamine d. Acetylcholine in ANS movment e. Nicotine in PNS f. Muscarinic in PNS 3. Neuropeptide transmitters a. Vasopressin, Oxytocin, Insulin, Somatostatin, Endorphins 4. Structures a. Cerebrum- LOC, mentation b. Cerebellum- coordination, balance c. Hypothalamus- coordinating center for PNS, endocrine d. Thalamus- sensation, reflexes e. Brainstem- HR, RR, BP, swallowing f. Reticular activating system- wakefulness, attention DEMENTING ILLNESS 1. Diffuse lewy body disease- progressive disease, tremors and early on hallucinations a. Treated with alz drugs, Seroquel or Abilify