BSN-205 Final Exam Hallmark Study Guide - Practice-Ready Answer Guide

BSN-205 Final Exam Hallmark Study Guide - Practice-Ready Answer Guide Superficial Squamous Cells - answer - Single cells Large, polygonal shape Pyknotic nucleus Intermediate cell - answer - Sheets, clusters, singles Large, polygonal shape Vesicular nucleus Parabasal cell - answer - Singles and sheets Medium, round cells Dense cytoplasm Navicular cells - answer - Singles and clusters Boat-shaped Cytoplasmic accumulation of glycogen (stains yellow) Slightly smaller than intermediate Endocervical cells - answer - Honeycomb sheets, picket fence/palisading, singles Columnar shape Vacuolated, delicate cytoplasm Endometrial cells - answer - 3-D ball or clusters Small cells Scant cytoplasm Indistinct cell borders Degenerated nucleus Superficial Stromal Cells - answer - Singles, pools, and loose aggregates Round cells Bubbly cytoplasm Round to oval to kidney bean shaped nucleus Deep Stromal Cell - answer - Double contour ball or loose aggregates Spindle shaped nucleus Wispy cytoplasm Doderlein bacilli - answer - Rod-shaped, 3-6 micrometers long, pale-blue in pap stain Actinomyces - answer - Branching Filamentous bacteria with associated clinging bacteria Leptothrix - answer - Thin, long, segmented filamentous rods, grey in color Shift - answer - Coccobacilli, purple in color, creates filmy granular background on cells and in background Chlamydia - answer - Cytoplasmic granular inclusions with red elementary bodies inside Candida - answer - Pseudohyphae and buds Trichomonas vaginalis - answer - Oval,pear or kite shaped, small, elliptical nucleus, +- cytoplasmic granules Pinworm egg; Enterobius vermicularis - answer - Ovoid, orange-pink color, double walled shell, larval structure in the middle Herpes - answer - Multinucleation, Molding of nuclei, Margination of chromatin, ground glass chromatin CMV (cytomegalovirus) - answer - Owl's eye- large round, basophilic intranuclear inclusion with prominent halo, +- cytoplasmic inclusions Molluscum contagiosum - answer - Molluscum bodies-dense eosinophilic cytoplasmic inclusions, pyknotic/degenerated nucleus pushed to periphery of the cell Immature Squamous Metaplastic Cells - answer - Cobblestone sheets and singles, medium round cells, dense cytoplasm Hyperkeratosis (HK) - answer - Clusters of anucleated squamous cells Parakeratosis (PK) - answer - Sheets, pearls, singles, miniature superficial cells, dense orangeophilic cytoplasm Pseudoparaleratosis (PPK) - answer - Singles, pools, linear arrays, small round endocervical cells, granular cytoplasm, eccentric pyknotic nucleus Inflammatory changes - answer - Nuclear enlargement (1.5-2x), hypochromatic chromatin, Nuclear membrane may be wrinkled, moth eaten cytoplasm, karyopylnosis, karyorrhexis, karyolysis, bi or multinucleation Chronic Follicular Cervicitis - answer - Tingible body macrophages, lymphocytes of varying maturation Granulomatous Cervicitis - answer - Epithelioid histiocytes, giant histiocytes, lymphocytes Atrophic vaginitis - answer - Parabasal cells with slight nuclear enlargement, neutrophils, granular background, mummified cells, blue blobs Folic acid deficiency - answer - Macrocytes( mature squamous cells with nuclear and cytoplasmic enlargement) Macrocytes - answer - Mature squamous cells with nuclear and cytoplasmic enlargement Pemphigus vulgaris - answer - Tzanck cells (round to polygonal parabasal sized cells, with dense cytoplasm) bar or bullet-shaped nucleolus Reactive cells - answer - Maintains parent arrangement, 1-5-2 times nuclear enlargement, prominent nucleoli Repair - answer - Streaming sheet, Macronucleoli in 80% of nuclei, Hypochromatic nucleus LSIL, HPV - answer - Large, polygonal cell, Koilocyte: small,smudgy nucleus, large perinuclear vacuole with dense cytoplasmic rim LSIL, Mild dysplasia - answer - Large, polygonal cells; Nucleus is 3x bigger than intermediate nucleus; hyperchromatic; Nucleus takes up no more that 1/3 of total cell area HSIL, moderate dysplasia - answer -