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NURS 423 Exam 2 Salgado 2026/2027 | Lecture Questions & Answers | Pharmacology, Anemia, Thyroid Disorders, Arthritis & Pain Management

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Comprehensive 41-page NURS 423 Exam 2 Salgado Lecture 2026/2027 study guide featuring detailed nursing pharmacology questions and provided answers covering disease management, medication mechanisms of action, clinical assessment, adverse effects, contraindications, and patient education. Key topics include anemia, sickle cell disease, iron and vitamin B12 deficiencies, anticoagulants, heparin, warfarin, direct oral anticoagulants, vitamin D deficiency, hyperthyroidism, hypothyroidism, osteoarthritis, rheumatoid arthritis, DMARDs, gout management, acute and chronic pain, opioid therapy, overactive bladder, urinary tract infections, benign prostatic hyperplasia (BPH), and erectile dysfunction medications. The material emphasizes medication selection, laboratory monitoring, drug interactions, treatment considerations, and clinical decision-making for nursing examinations. Relevant academic references include Lehne's Pharmacology for Nursing Care (Burchum & Rosenthal), Pharmacotherapeutics for Advanced Practice Nurse Prescribers (Woo & Robinson), and Goodman & Gilman's The Pharmacological Basis of Therapeutics. These are supplementary references rather than verified citations from the uploaded notes. Relevant Students: BSN students, MSN students, Family Nurse Practitioner (FNP) students, Adult-Gerontology Nurse Practitioner (AGNP) students, advanced practice registered nursing students, nursing pharmacology students, primary care nursing students, and registered nurses preparing for pharmacology examinations. Keywords: NURS 423 Exam 2, NURS 423 Salgado lecture, NURS 423 exam 2026, NURS 423 exam 2027, NURS 423 questions and answers, nursing pharmacology exam, advanced pharmacology nursing, anemia treatment, sickle cell anemia, iron deficiency anemia, anticoagulant medications, warfarin monitoring, heparin pharmacology, thyroid medications, hyperthyroidism treatment, hypothyroidism management, rheumatoid arthritis medications, osteoarthritis treatment, DMARDs pharmacology, methotrexate monitoring, gout pharmacology, pain management nursing, opioid analgesics, overactive bladder medications, urinary tract infection treatment, BPH pharmacology, erectile dysfunction medications, FNP pharmacology exam, nursing lecture study guide

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NURS 423 Exam 2 Salgado
Lecture 2026/2027 Expert
Verifed Ace the Test



Anemia is a ___ due to - ANSWER ✔✔Symptom; blood loss,

nutrition, mal-absorption, occurs with inflammation processes,

malignancies, inherited- like sickle cell and Thalassemia


Sickle cell anemia - ANSWER ✔✔Defective form hemoglobin S;

diagnosis at birth with newborn screen; pain crisis, abnormal shaped

cells so they cannot travel through vessels well and cause occlusive

crisis and stroke.


Sickle cell anemia treatment - ANSWER ✔✔Antibiotics as

prophylaxtic until age 5; pain meds; bone marrow transplant;

,Hydroxyurea-


Hydroxyurea - ANSWER ✔✔increases hemoglobin F levels, water

levels of RBCs, alters adhesion of cells to endothelial. Decreases crisis

and s/s sickle cell


iron deficiency anemia due to - ANSWER ✔✔decreased poor intake,

inadequate absorption in GI tract, and or increase in iron demand.


iron deficiency anemia labs monitor - ANSWER ✔✔Low: ferritin,

serum iron

High: TBIC


Iron def anemia treatment - ANSWER ✔✔100-200 elemental iron per

day. Ferrous sulfate 325mg tablets. Pediatrics are weight based.

Increase vitamin C d/t it increased absorption of iron.

Dont give IV ferrous gluconate and dextran in primary care


Anemia of chronic disease - ANSWER ✔✔Erythropoietin production

in kidneys is decreased, like in end stage renal disease.

Tx with Erythropoietin replacement


B12 deficiency anemia common in - ANSWER ✔✔Mostly in elderly,

alcoholics b/c they dont eat only drink, vegans, weight loss surgery

,B12 deficiency anemia d/t - ANSWER ✔✔Lack of intrinsic factor


Macrocytic

Disorder of DNA synthesis


B12 deficiency anemia - ANSWER ✔✔Tx Parenteral B12, no intrinsic

factor so can't absorb oral medications.

Check hematrocrit, increases in 3 weeks and normalizes in 3 months


Folate deficiency anemia results in - ANSWER ✔✔large functionally

immature erthyrocytes aka megablasts


Megablasts - ANSWER ✔✔Large functionally immature erthyrocytes

seen in folate def


Folate deficiency anemia d/t and treatment - ANSWER

✔✔inadequate intake, absorption/utilization, increased demands and/or

increased excretion

Tx- 1 mg folic acid daily- starting point, higher if needed


Goal of anticoagulation medication therapy - ANSWER ✔✔Primary

goal prevent stroke

in patients with A Fib, prosthetic valve, hx cardioembolic event



3
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, DVT and PE, prevent extension of thrombus or new ones

Post op orthopedic surgery, Aspirin to decrease risk of DVT/PE


Unfractionated heparin MOA - ANSWER ✔✔Prevents reaction that

leads to clotting, doesnt affect clotting time

Give parentally

Is heparin protein bound?


What labs monitor? - ANSWER ✔✔Yes, highly


Monitor aPTT, liver function??


Antidote of heparin - ANSWER ✔✔protamine sulfate


low molecular weight heparin MOA - ANSWER ✔✔Lovenox


Prevents activation Factor X and thrombin factor

Assess risk for GI bleed, blood in urine and sputum


Monitor Lovenox? - ANSWER ✔✔No, but if you want then monitor

anti-Xa


Is lovenox cleared renally? - ANSWER ✔✔Yes


Does Lovenox have an anitdote? - ANSWER ✔✔No


Enoxaparin (Lovenox) - ANSWER ✔✔low molecular weight heparin

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