NR 293 Pharmacology Exam 1 Chamberlain |
2026/2027 | Newest Actual Exam With
Complete Questions And Correct Answers
With Detailed Rationales | Already Graded
A+| |Brand New Version!!
Which process describes the movement of a drug from the site of administration into the
bloodstream?
A) Distribution
B) Absorption
C) Metabolism
D) Excretion
Answer
Answer: B
Rationale
Absorption transfers drug from administration site to systemic circulation. Distribution is movement to
tissues.
Question 2
The first-pass effect primarily affects drugs administered by which route?
A) Intravenous
B) Oral
C) Subcutaneous
D) Inhalation
Answer
,Answer: B
Rationale
Oral drugs pass through the liver before reaching systemic circulation, reducing bioavailability.
Question 3
Which organ is primarily responsible for drug metabolism?
A) Kidney
B) Liver
C) Lung
D) Heart
Answer
Answer: B
Rationale
The liver contains cytochrome P450 enzymes that metabolize most drugs.
Question 4
A drug with a narrow therapeutic index requires:
A) Less frequent dosing
B) Close monitoring of drug levels
C) Higher doses for effect
D) No monitoring
Answer
Answer: B
Rationale
2
,Narrow therapeutic index means small differences between therapeutic and toxic doses; monitor levels
closely.
Question 5
Which drug form is absorbed most rapidly?
A) Tablet
B) Liquid solution
C) Capsule
D) Enteric-coated tablet
Answer
Answer: B
Rationale
Solutions are already dissolved and absorbed faster than solid dosage forms.
Question 6
An agonist is a drug that:
A) Blocks receptor activity
B) Activates a receptor to produce an effect
C) Destroys receptors
D) Has no effect on receptors
Answer
Answer: B
Rationale
Agonists bind and activate receptors. Antagonists block receptors without activating them.
3
, Question 7
Which phase of drug development involves human testing for safety and efficacy?
A) Preclinical
B) Clinical trials
C) FDA review
D) Post-marketing surveillance
Answer
Answer: B
Rationale
Clinical trials (phases I-III) test drugs in humans. Preclinical is animal/lab testing.
Question 8
A medication order reads: “Give 0.5 mg PO daily.” The available tablet is 0.25 mg. How many
tablets will the nurse administer?
A) 0.5 tablet
B) 2 tablets
C) 1 tablet
D) 3 tablets
Answer
Answer: B
Rationale
0.5 mg ÷ 0.25 mg/tablet = 2 tablets.
Question 9
The “rights” of medication administration include all EXCEPT:
4
2026/2027 | Newest Actual Exam With
Complete Questions And Correct Answers
With Detailed Rationales | Already Graded
A+| |Brand New Version!!
Which process describes the movement of a drug from the site of administration into the
bloodstream?
A) Distribution
B) Absorption
C) Metabolism
D) Excretion
Answer
Answer: B
Rationale
Absorption transfers drug from administration site to systemic circulation. Distribution is movement to
tissues.
Question 2
The first-pass effect primarily affects drugs administered by which route?
A) Intravenous
B) Oral
C) Subcutaneous
D) Inhalation
Answer
,Answer: B
Rationale
Oral drugs pass through the liver before reaching systemic circulation, reducing bioavailability.
Question 3
Which organ is primarily responsible for drug metabolism?
A) Kidney
B) Liver
C) Lung
D) Heart
Answer
Answer: B
Rationale
The liver contains cytochrome P450 enzymes that metabolize most drugs.
Question 4
A drug with a narrow therapeutic index requires:
A) Less frequent dosing
B) Close monitoring of drug levels
C) Higher doses for effect
D) No monitoring
Answer
Answer: B
Rationale
2
,Narrow therapeutic index means small differences between therapeutic and toxic doses; monitor levels
closely.
Question 5
Which drug form is absorbed most rapidly?
A) Tablet
B) Liquid solution
C) Capsule
D) Enteric-coated tablet
Answer
Answer: B
Rationale
Solutions are already dissolved and absorbed faster than solid dosage forms.
Question 6
An agonist is a drug that:
A) Blocks receptor activity
B) Activates a receptor to produce an effect
C) Destroys receptors
D) Has no effect on receptors
Answer
Answer: B
Rationale
Agonists bind and activate receptors. Antagonists block receptors without activating them.
3
, Question 7
Which phase of drug development involves human testing for safety and efficacy?
A) Preclinical
B) Clinical trials
C) FDA review
D) Post-marketing surveillance
Answer
Answer: B
Rationale
Clinical trials (phases I-III) test drugs in humans. Preclinical is animal/lab testing.
Question 8
A medication order reads: “Give 0.5 mg PO daily.” The available tablet is 0.25 mg. How many
tablets will the nurse administer?
A) 0.5 tablet
B) 2 tablets
C) 1 tablet
D) 3 tablets
Answer
Answer: B
Rationale
0.5 mg ÷ 0.25 mg/tablet = 2 tablets.
Question 9
The “rights” of medication administration include all EXCEPT:
4
