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Exam (elaborations)

PCB4843 Week 5 - Questions with Correct Answers (Verified Update)

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PCB4843 Week 5: 56 exam questions with verified correct answers, for PCB 4843. 4 pages, 2026 verified update. Sample questions covered: ionotropic/transmitter-gated receptors | metabotropic/g-protein coupled receptors | three guidelines for the definition of a neurotransmitter | immunohistochemistry

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PCB4843 Week 5 - Questions with Correct Answers
(Verified Update)
56 questions with answers
Topic: PCB4843 Week 5

1. ionotropic/transmitter-gated receptors
Answer: channel and binding are on the same protein

2. metabotropic/g-protein coupled receptors
Answer: channel and binding are on different proteins

3. three guidelines for the definition of a neurotransmitter
Answer: 1. is it synthesized and stored in a presynaptic neuron

4. immunohistochemistry
Answer: identifying specific molecules (proteins and enzymes) in a cell

5. in situ hybridization
Answer: shows mRNA/gene expression

6. experiment: does a cell release glutamate?
Answer: found in every cell, but not every cell releases it

7. why is it difficult to determine if an NT is released from an axon terminal
Answer: because there is a diverse mix of synapses with different NTs

8. optogenetics to selectively release orexin
Answer: orexin-cre mouse x channelrhodopsin2-loxP mouse

9. microiontophoresis
Answer: pipetting a charged molecule and applying current to release a small amount

10. receptor subtype
Answer: each of the different receptors a neurotransmitter binds to

11. nicotinic receptor antagonist
Answer: curare

12. muscarinic receptor antagonist
Answer: atropine

13. nicotinic and muscarinic receptors are both associated with which NT
Answer: acetylcholine

14. AMPA receptor antagonist
Answer: CNQX

15. NMDA receptor antagonist
Answer: AP5

16. AMPA and NMDA receptors are both associated with which NT
Answer: glutamate



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