NURS 5334 ADVANCED
PHARMACOLOGY TEST 2 ACTUAL PAPER
WITH SOLVED QUESTIONS
◉ Arguments for full prescriptive authority
Answer: - APRNs are educated to practice and prescribe
independently without supervision
- National examinations validate ability to provide safe competent
care
- Licensure ensures compliance with standards to promote public
health and safety - Limited prescriptive authority creates
numerous barriers to quality, affordable, & accessible patient care
◉ Drug selection factors
Answer: cost, guidelines, availability, interactions, side effects,
allergies, liver & renal function, need for monitoring, special
populations
◉ Elements needed to complete a prescription
Answer: - Prescriber name, license number, and contact
information
- Prescriber DEA number, if applicable
- Patient name and date of birth
,- Patient allergies
- Name of medication
- Indication of medication
- Medication strength (e.g., 25 mg, 500 mg/mL)
- Dose of medication and frequency (e.g., 12.5 mg once daily)
- Number of tablets/capsules to dispense
- Number of refills
◉ Pharmokinetics
Answer: the study of drugs within the body, absorption ,
distribution, metabolism, excretion
◉ 3 ways drugs cross cell membrane
Answer: 1. channels & pores
2. transport systems (p glycoprotein)
3. direct penetration of membrane ( most common -> drugs too
large to pass through pores & channels)
◉ absorption
Answer: the movement of a drug from its site of administration
into the blood
rate of absorption determines how soon effects will begin
, amount of absorption determine intensity of effects
◉ factors affecting absorption
Answer: rate of dissolution, surface area, blood flow, lipid
solubility, pH partitioning
◉ P-glycoprotein
Answer: Transmembrane protein that transports a wide variety of
drugs out of cells
◉ How does the liver aid in pharmacokinetics?
Answer: transports drugs into bile for elimination
◉ How do the kidneys aid in pharmacokinetics?
Answer: pumps drugs into urine for excretion
◉ How does the placenta aid in pharmacokinetics?
Answer: transports drugs back into the maternal blood
◉ How does the brain aid in pharmacokinetics?
Answer: pumps drugs into blood to limit drugs' access to the
brain
◉ passive diffusion
PHARMACOLOGY TEST 2 ACTUAL PAPER
WITH SOLVED QUESTIONS
◉ Arguments for full prescriptive authority
Answer: - APRNs are educated to practice and prescribe
independently without supervision
- National examinations validate ability to provide safe competent
care
- Licensure ensures compliance with standards to promote public
health and safety - Limited prescriptive authority creates
numerous barriers to quality, affordable, & accessible patient care
◉ Drug selection factors
Answer: cost, guidelines, availability, interactions, side effects,
allergies, liver & renal function, need for monitoring, special
populations
◉ Elements needed to complete a prescription
Answer: - Prescriber name, license number, and contact
information
- Prescriber DEA number, if applicable
- Patient name and date of birth
,- Patient allergies
- Name of medication
- Indication of medication
- Medication strength (e.g., 25 mg, 500 mg/mL)
- Dose of medication and frequency (e.g., 12.5 mg once daily)
- Number of tablets/capsules to dispense
- Number of refills
◉ Pharmokinetics
Answer: the study of drugs within the body, absorption ,
distribution, metabolism, excretion
◉ 3 ways drugs cross cell membrane
Answer: 1. channels & pores
2. transport systems (p glycoprotein)
3. direct penetration of membrane ( most common -> drugs too
large to pass through pores & channels)
◉ absorption
Answer: the movement of a drug from its site of administration
into the blood
rate of absorption determines how soon effects will begin
, amount of absorption determine intensity of effects
◉ factors affecting absorption
Answer: rate of dissolution, surface area, blood flow, lipid
solubility, pH partitioning
◉ P-glycoprotein
Answer: Transmembrane protein that transports a wide variety of
drugs out of cells
◉ How does the liver aid in pharmacokinetics?
Answer: transports drugs into bile for elimination
◉ How do the kidneys aid in pharmacokinetics?
Answer: pumps drugs into urine for excretion
◉ How does the placenta aid in pharmacokinetics?
Answer: transports drugs back into the maternal blood
◉ How does the brain aid in pharmacokinetics?
Answer: pumps drugs into blood to limit drugs' access to the
brain
◉ passive diffusion
