NR 293 PHARMACOLOGY WEEK 1 STUDY GUIDE | EDAPTS
REVIEW, KEY CONCEPTS & PRACTICE QUIZ
1. Which changes related to drug metabolism occur with age?
Metabolism of drugs is not affected by age.
Drugs are metabolized into different compounds in older adults,
resulting in unexpected adverse medication outcomes.
Drugs are metabolized more quickly in older adults.
The liver metabolizes drugs less efficiently with age.
2. If a patient has a genetic variant that affects the metabolism of fluoxetine,
what might be a potential outcome of this genetic difference?
Fluoxetine will work better than expected.
Increased side effects and reduced efficacy of fluoxetine.
No change in the effectiveness of fluoxetine.
Improved efficacy and fewer side effects.
3. If a patient requires rapid pain relief, which medication administration route
would be most appropriate and why?
Subcutaneous, because it is less invasive.
Intramuscular, because it allows for slower absorption.
Oral, because it is the easiest method for patients.
Intravenous, because it provides immediate drug delivery into the
bloodstream.
4. Pharmacodynamics is defined as:
, time for half of the drug to be eliminated from the body.
absorption, metabolism, excretion rates.
mechanisms by which drugs produce biochemical and physical
changes in the body.
prevents alteration of drugs in the stomach/small intestine.
5. What term describes a substance that produces a physiological effect when
administered to a living organism?
enzyme
neurotransmitter
drug
hormone
6. If a client is advised to take a daily multivitamin to enhance their immune
system, which pharmacological principle does this scenario illustrate?
The role of preventive therapy in enhancing health.
The significance of therapeutic indices in drug safety.
The impact of genetics on drug metabolism.
The importance of pharmacodynamics in drug action.
7. What is the primary characteristic of a non-competitive antagonist in
pharmacology?
It has no effect on receptor activity.
It enhances the effect of the agonist.
It binds to a site other than the active site on the receptor.
It competes with the agonist for the active site.
,8. Describe how a high 2D6 polymorphism might influence the dosing of
warfarin in a patient with atrial fibrillation.
A high 2D6 polymorphism may require adjustments in warfarin
dosing due to altered metabolism.
A high 2D6 polymorphism decreases the effectiveness of warfarin.
A high 2D6 polymorphism increases the risk of warfarin overdose.
A high 2D6 polymorphism has no effect on warfarin dosing.
9. If a patient requires rapid pain relief, which drug administration route would
be most appropriate and why?
Intravenous, because it provides immediate drug delivery into the
bloodstream.
Intramuscular, because it is less painful than intravenous.
Oral, because it is the easiest method for patients.
Topical, because it minimizes systemic side effects.
10. Occur when food changes the expected effect of a drug
Drug- Disease
Drug-Food
Drug-drug interaction
11. What is the primary type of therapy used to treat HIV?
Hormone therapy
Antiretroviral therapy
Antibiotic therapy
, Chemotherapy
12. What is the primary purpose of oxycodone/acetaminophen in the context of
cancer treatment?
Antibiotic treatment
Hormonal therapy
Chemotherapy
Pain relief
13. How does aging generally affect the metabolism and excretion of
medications in older adults?
Aging decreases drug metabolism and excretion.
Aging has no significant impact on drug metabolism and excretion.
Aging only affects drug metabolism, not excretion.
Aging increases drug metabolism and excretion.
14. If a patient has a known genetic mutation affecting drug metabolism, what
should a healthcare provider consider when prescribing medication?
Adjust the medication dosage based on the patient's genetic
profile.
Ignore the genetic profile and follow standard dosing guidelines.
Prescribe the same dosage as for other patients.
Increase the dosage to ensure effectiveness.
15. What is a partial agonist in pharmacology?
A drug that blocks a receptor's activity completely.
REVIEW, KEY CONCEPTS & PRACTICE QUIZ
1. Which changes related to drug metabolism occur with age?
Metabolism of drugs is not affected by age.
Drugs are metabolized into different compounds in older adults,
resulting in unexpected adverse medication outcomes.
Drugs are metabolized more quickly in older adults.
The liver metabolizes drugs less efficiently with age.
2. If a patient has a genetic variant that affects the metabolism of fluoxetine,
what might be a potential outcome of this genetic difference?
Fluoxetine will work better than expected.
Increased side effects and reduced efficacy of fluoxetine.
No change in the effectiveness of fluoxetine.
Improved efficacy and fewer side effects.
3. If a patient requires rapid pain relief, which medication administration route
would be most appropriate and why?
Subcutaneous, because it is less invasive.
Intramuscular, because it allows for slower absorption.
Oral, because it is the easiest method for patients.
Intravenous, because it provides immediate drug delivery into the
bloodstream.
4. Pharmacodynamics is defined as:
, time for half of the drug to be eliminated from the body.
absorption, metabolism, excretion rates.
mechanisms by which drugs produce biochemical and physical
changes in the body.
prevents alteration of drugs in the stomach/small intestine.
5. What term describes a substance that produces a physiological effect when
administered to a living organism?
enzyme
neurotransmitter
drug
hormone
6. If a client is advised to take a daily multivitamin to enhance their immune
system, which pharmacological principle does this scenario illustrate?
The role of preventive therapy in enhancing health.
The significance of therapeutic indices in drug safety.
The impact of genetics on drug metabolism.
The importance of pharmacodynamics in drug action.
7. What is the primary characteristic of a non-competitive antagonist in
pharmacology?
It has no effect on receptor activity.
It enhances the effect of the agonist.
It binds to a site other than the active site on the receptor.
It competes with the agonist for the active site.
,8. Describe how a high 2D6 polymorphism might influence the dosing of
warfarin in a patient with atrial fibrillation.
A high 2D6 polymorphism may require adjustments in warfarin
dosing due to altered metabolism.
A high 2D6 polymorphism decreases the effectiveness of warfarin.
A high 2D6 polymorphism increases the risk of warfarin overdose.
A high 2D6 polymorphism has no effect on warfarin dosing.
9. If a patient requires rapid pain relief, which drug administration route would
be most appropriate and why?
Intravenous, because it provides immediate drug delivery into the
bloodstream.
Intramuscular, because it is less painful than intravenous.
Oral, because it is the easiest method for patients.
Topical, because it minimizes systemic side effects.
10. Occur when food changes the expected effect of a drug
Drug- Disease
Drug-Food
Drug-drug interaction
11. What is the primary type of therapy used to treat HIV?
Hormone therapy
Antiretroviral therapy
Antibiotic therapy
, Chemotherapy
12. What is the primary purpose of oxycodone/acetaminophen in the context of
cancer treatment?
Antibiotic treatment
Hormonal therapy
Chemotherapy
Pain relief
13. How does aging generally affect the metabolism and excretion of
medications in older adults?
Aging decreases drug metabolism and excretion.
Aging has no significant impact on drug metabolism and excretion.
Aging only affects drug metabolism, not excretion.
Aging increases drug metabolism and excretion.
14. If a patient has a known genetic mutation affecting drug metabolism, what
should a healthcare provider consider when prescribing medication?
Adjust the medication dosage based on the patient's genetic
profile.
Ignore the genetic profile and follow standard dosing guidelines.
Prescribe the same dosage as for other patients.
Increase the dosage to ensure effectiveness.
15. What is a partial agonist in pharmacology?
A drug that blocks a receptor's activity completely.
