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Clinical Medical Assistant Certification (CMAC) Exam

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The CMAC is a clinical medical assistant certification offered by the American Medical Certification Association (AMCA), designed to validate the entry-level clinical and administrative competencies of medical assistants. The exam consists of approximately 175 questions (160 scored questions + 15 unscored pretest questions), with a time limit of 2 hours and 30 minutes, and a passing score of 70%. The content covers four major domains: Clinical Medical Assisting (60%), Administrative Medical Assisting (26%), Professionalism (10%), and Medical Law and Ethics (4%). Core test content includes: phlebotomy (blood collection order), EKG lead placement, infection control and OSHA standards, medication administration (five rights), vital signs measurement, ICD-10-CM and CPT coding basics, HIPAA privacy and security rules, SOAP note format, etc. The exam fee is **$139** (an additional $35 for live remote proctoring). The certification is valid for 2 years, requiring 10 continuing education credits for renewal. It should be noted that the search results contain conflicting information regarding CMAC exam details: some sources indicate 200 questions, 3.5 hours, with content covering phlebotomy, EKG, anatomy and physiology, law and ethics, safety/infection control, medical office/patient care, and healthcare systems. It is recommended to refer to the official AMCA website for the most current exam specifications.


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October 18, 2026
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