HESI Pharmacology Practice Test with
correct answers 100% 2026
The nurse reviews the new prescription, phenelzine (Nardil), a monoamine oxidase inhibitor
(MAOI), for a client with depression on the psychiatric unit. Which information is most
important for the nurse to assess?
A. Consumption of any alcohol or tyramine rich foods
B. Reports of nausea or vomiting
C. Therapeutic serum drug levels
D. Blood pressure and pulse prior to taking each dose - Correct Answer A
The nurse is administering haloperidol 0.5 mg IM PRN to a client for the first time. What side
effects should the nurse assess thr client during the initial dose?
A. Bradykinesia
B. Dystonia
C. Somatization
D. Akathisia - Correct Answer B
While reviewing the client's electronic medical record (EMR), the nurse assesses a client who is
at risk for a possible interaction with an over-the-counter (OTC) decongestant. Which client
health history should the nurse report to the health care provider concerning the OTC
medication? (Select all that apply)
A. Type 1 diabetes mellitus (DM)
B. Closed angle glaucome
C. Chronic hypertension
D. Rheumatoid arthritis
,E. Crohn's disease - Correct Answer B,C
A client prescribed ipratropium reports nausea, blurred vision, headaches, and insomnia after
using the inhaler. Which action should the nurse implement first?
A. Withhold the medication and report symptoms and vital signs to the healthcare provider
B. Give PRN medication for nausea and vomiting and evaluate client in 30 minutes
C. reassure client that the ipratropium given will alleviate the symptoms
D. Delay administration of ipratropium until the next maintenance medication is scheduled -
Correct Answer A
A client diagnosed with multiple sclerosis is experiencing profound weakness, blurry vision, and
shooting pains in both legs. Which medication is considered the best course of treatment for
the nurse to administer?
A. High dose methylprednisolone intravenously
B. Baclofen three times a day
C. Broad spectrum antibiotic coverage orally
D. Immunomodulatory drug therapy periodically - Correct Answer A
The nurse administers 30 mL of lactulose for a client with stage 2 hepatic encephalopathy.
Which assessment finding would indicate the medication is being therapeutic?
A. A decrease in blood ammonia levels
B. A softening in the stools
C. An increase in glucose absorption
D. A suppression of gut acidification - Correct Answer A
, The nurse is teaching a client who is newly diagnosed with type 1 diabetes about neutral
protamine Hagedor (NPH) insulin. Which statement by the client indicates an understanding of
how the medication works?
A. It facilitates the transport of glucose into the cells
B. It stimulates the function of beta cells in the pancreas
C. It increases the intracellular receptor site sensitivity
D. It delays the carbohydrate digestion and absorption - Correct Answer A
The nurse should withhold which medication if a client reports nausea, vomiting, and diarrhea?
A. Colchicine (Mitigare, Colcrys)
B. Erythromycin (E-mycin)
C. Naproxen (Aleve, Naprosyn)
D. Labetolol (Normodyne) - Correct Answer A
A client newly prescribed esomeprazole for gastroesophageal reflux disease (GERD) asks the
nurse how the medication will help. Which is the best explanation to provide the client?
A. It will promote rapid tissue healing
B. It will increase gastric emptying
C. It will improve esophageal peristalsis
D. It will neutralize gastric secretions - Correct Answer A
correct answers 100% 2026
The nurse reviews the new prescription, phenelzine (Nardil), a monoamine oxidase inhibitor
(MAOI), for a client with depression on the psychiatric unit. Which information is most
important for the nurse to assess?
A. Consumption of any alcohol or tyramine rich foods
B. Reports of nausea or vomiting
C. Therapeutic serum drug levels
D. Blood pressure and pulse prior to taking each dose - Correct Answer A
The nurse is administering haloperidol 0.5 mg IM PRN to a client for the first time. What side
effects should the nurse assess thr client during the initial dose?
A. Bradykinesia
B. Dystonia
C. Somatization
D. Akathisia - Correct Answer B
While reviewing the client's electronic medical record (EMR), the nurse assesses a client who is
at risk for a possible interaction with an over-the-counter (OTC) decongestant. Which client
health history should the nurse report to the health care provider concerning the OTC
medication? (Select all that apply)
A. Type 1 diabetes mellitus (DM)
B. Closed angle glaucome
C. Chronic hypertension
D. Rheumatoid arthritis
,E. Crohn's disease - Correct Answer B,C
A client prescribed ipratropium reports nausea, blurred vision, headaches, and insomnia after
using the inhaler. Which action should the nurse implement first?
A. Withhold the medication and report symptoms and vital signs to the healthcare provider
B. Give PRN medication for nausea and vomiting and evaluate client in 30 minutes
C. reassure client that the ipratropium given will alleviate the symptoms
D. Delay administration of ipratropium until the next maintenance medication is scheduled -
Correct Answer A
A client diagnosed with multiple sclerosis is experiencing profound weakness, blurry vision, and
shooting pains in both legs. Which medication is considered the best course of treatment for
the nurse to administer?
A. High dose methylprednisolone intravenously
B. Baclofen three times a day
C. Broad spectrum antibiotic coverage orally
D. Immunomodulatory drug therapy periodically - Correct Answer A
The nurse administers 30 mL of lactulose for a client with stage 2 hepatic encephalopathy.
Which assessment finding would indicate the medication is being therapeutic?
A. A decrease in blood ammonia levels
B. A softening in the stools
C. An increase in glucose absorption
D. A suppression of gut acidification - Correct Answer A
, The nurse is teaching a client who is newly diagnosed with type 1 diabetes about neutral
protamine Hagedor (NPH) insulin. Which statement by the client indicates an understanding of
how the medication works?
A. It facilitates the transport of glucose into the cells
B. It stimulates the function of beta cells in the pancreas
C. It increases the intracellular receptor site sensitivity
D. It delays the carbohydrate digestion and absorption - Correct Answer A
The nurse should withhold which medication if a client reports nausea, vomiting, and diarrhea?
A. Colchicine (Mitigare, Colcrys)
B. Erythromycin (E-mycin)
C. Naproxen (Aleve, Naprosyn)
D. Labetolol (Normodyne) - Correct Answer A
A client newly prescribed esomeprazole for gastroesophageal reflux disease (GERD) asks the
nurse how the medication will help. Which is the best explanation to provide the client?
A. It will promote rapid tissue healing
B. It will increase gastric emptying
C. It will improve esophageal peristalsis
D. It will neutralize gastric secretions - Correct Answer A
