Basic and Clinical Pharmacology, 16th Edition – Katzung | Complete Test Bank (Chapters 1–66) 2026–2027

TEST BANK FOR BASIC AND CLINICAL
ff ff ff ff ff




PHARMACOLOGY16TH EDITION KATZUNG’S TESTBANK
ff f ff ff ff




/ALL CHS 1-
ff ff ff




66/COMPLETE GUIDE 2026-2027 ff ff

,CH 1. Introduction: The Nature of Drugs & Drug Development & Regulation
ff ff ff ff ff ff ff ff ff ff ff




1. A nurse working in radiology administers iodine to a hospital client who
ff ff ff ff ff ff ff ff ff ff ff


is having a computed tomography (CT) scan. The nursing attendant
ff ff ff ff ff ff ff ff ff ff


working on the oncology unit administers chemotherapy to hospital
ff ff ff ff ff ff ff ff ff


clients who have cancer. At the Public Health Department, a nursing
ff ff ff ff ff ff ff ff ff ff ff


attendant administers a measles-mumps-rubella (MMR) vaccine to a 14-
ff ff ff ff f ff ff ff ff ff


month-old child as a routine immunization. Which branch of
ff ff ff ff ff ff ff ff


pharmacology best describes the actions of all three
ff ff ff ff ff ff ff ff


nursing attendants? ff



A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
ACCURATE CHOICE:- ff B
Reasoning :->>>>>> ff




Pharmacology is the study of the biologic effects of chemicals. Nursing ff ff ff ff ff ff ff ff ff ff


attendants are involved with clinical pharmacology or
ff ff ff ff ff ff ff


pharmacotherapeutics, which is a branch of pharmacology that deals with
ff ff ff ff ff ff ff ff ff ff


the uses of drugs to treat,prevent, and diagnose disease. The radiology
ff ff ff ff ff ff f ff ff ff ff ff


nursing attendant is administering a drug to help diagnose a disease. The
ff ff ff ff ff ff ff ff ff ff ff ff


oncology nursing attendant is administering a drug to help treat a disease.
ff ff ff ff ff ff ff ff ff ff ff ff


Pharmacoeconomics includes any costs involved in drug therapy.
ff ff ff ff ff ff ff ff


Pharmacodynamics involves how a drug affects the body and ff ff ff ff ff ff ff ff


pharmacokinetics is how the body acts on the body. ff ff ff ff ff ff ff ff




2. When involved in phase III drug evaluation studies,
ff ff ff ff ff ff ff


whatresponsibilities would the nursing attendant have?
ff f ff ff ff ff ff




A) Working with animals who are given experimental drugs
ff ff ff ff ff ff ff




B) Choosing appropriate hospital clients to be involved in the drug study
ff ff ff ff ff ff ff ff ff ff




C) Monitoring and observing hospital clients closely for adverse effects
ff ff ff ff ff ff ff ff




D) Conducting research to determine effectiveness of the drug ff ff ff ff ff ff ff

,ACCURATE CHOICE:- ff C
Reasoning:->>>>>>

Phase III studies involve use of a drug in a vast clinical population in
ff ff ff ff ff ff ff ff ff ff ff ff ff


whichhospital clients are asked to record any symptoms they experience
ff f ff ff ff ff ff ff ff ff ff


while taking the drugs. Nursing attendants may be responsible for helping
ff ff ff ff ff ff ff ff ff ff ff


collect and analyzethe information to be shared with the Food and Drug
ff ff ff f ff ff ff ff ff ff ff ff ff


Administration (FDA)but would not conduct research independently
ff ff f ff ff ff ff ff


because nursing attendants donot prescribe medications. Use of animals
ff ff ff ff f ff ff ff ff ff


in drug testing is done in the preclinical trials. Select hospital clients who
ff ff ff ff ff ff ff ff ff ff ff ff ff


are involved in phase II studies to participate in studies where the
ff ff ff ff ff ff ff ff ff ff ff ff


participants have the disease the drug is intended to treat. These hospital
ff ff ff ff ff ff ff ff ff ff ff ff


clients are monitored closely for drug action and adverse effects. Phase I
ff ff ff ff ff ff ff ff ff ff ff ff


studies involve healthy human volunteers who are usually paid for their
ff ff ff ff ff ff ff ff ff ff ff


participation. Nursing attendants may observe for
ff ff ff ff ff ff


adverse effects and toxicity. ff ff ff




3. A physician has ordered intramuscular (IM) injections of morphine, a
ff ff ff ff ff ff ff ff ff


narcotic, every 4 hours as needed for pain in a motor vehicle accident
ff ff ff ff ff ff ff ff ff ff ff ff ff


victim.The nursing attendant is aware this drug has a high abuse
ff f ff ff ff ff ff ff ff ff ff ff


potential. Under what category would morphine be classified?
ff ff ff ff ff ff ff ff




A) Schedule I ff




B) Schedule II ff




C) Schedule III ff




D) Schedule IV ff




ACCURATE CHOICE:- ff B
Reasoning:->>>>>>

Narcotics with a high abuse potential are classified as Schedule II drugs
ff ff ff ff ff ff ff ff ff ff ff


because of severe dependence liability. Schedule I drugs have high abuse
ff ff ff ff ff ff ff ff ff ff ff


potential and no accepted medical use. Schedule III drugs have a lesser
ff ff ff ff ff ff ff ff ff ff ff ff


abuse potential than II and an accepted medical use. Schedule IV drugs
ff ff ff ff ff ff ff ff ff ff ff ff


havelow abuse potential and limited dependence liability.
ff f ff ff ff ff ff ff




4. What concept is considered when generic drugs are substituted for
ff ff ff ff ff ff ff ff ff


brandname drugs?
ff f ff




A) Bioavailability

, Page 5 of 822 ff ff ff




B) Critical concentration ff




C) Distribution
D) Half-life
ACCURATE CHOICE:-A
ff




Reasoning:->>>>>>

Bioavailability is the portion of a dose of a drug that reaches the systemic ff ff ff ff ff ff ff ff ff ff ff ff ff


circulation and is available to act on body cells. Binders used in a
ff ff ff ff ff ff ff ff ff ff ff ff ff


generic drug may not be the same as those used in the brand name drug.
ff ff ff ff ff ff ff ff ff ff ff ff ff ff ff


Therefore, the way the body breaks down and uses the drug may differ,
ff ff ff ff ff ff ff ff ff ff ff ff ff


which may eliminate a generic drug substitution. Critical concentration is
ff ff ff ff ff ff ff ff ff ff


the amount ofa drug that is needed to cause a therapeutic effect and
ff ff ff f ff ff ff ff ff ff ff ff ff ff


should not differ between generic and brand name medications.
ff ff ff ff ff ff ff ff ff


Distribution is the phase of pharmacokinetics, which involves the
ff ff ff ff ff ff ff ff ff


movement of a drug to the bodys tissues and is the same in generic and
ff ff ff ff ff ff ff ff ff ff ff ff ff ff ff


brand name drugs. A drugs half-life isthe time it takes for the amount of
ff ff ff ff ff ff ff f ff ff ff ff ff ff ff


drug to decrease to half the peak level, which should not change when
ff ff ff ff ff ff ff ff ff ff ff ff ff


substituting a generic medication.
ff ff ff f f




5. A nursing attendant is assessing the hospital clients home medication use. After
f ff ff ff ff ff ff ff ff ff ff


listening to the hospital client list current medications, the nursing
ff ff ff ff ff ff ff ff ff


attendant askswhat priority question?
ff ff f ff ff




A) Do you take any generic medications?
ff ff ff ff ff




B) Are any of these medications orphan drugs?
ff ff ff ff ff ff




C) Are these medications safe to take during pregnancy?
ff ff ff ff ff ff ff




D) Do you take any over-the-counter medications?
ff ff ff ff ff




ACCURATE CHOICE:-ff D
Reasoning:->>>>>>

It is important for the nursing attendant to specifically question use of
ff ff ff ff ff ff ff ff ff ff ff


over- the-counter medications because hospital clients may not consider
ff ff ff ff ff ff ff ff ff


them important. The hospital client is unlikely to know the meaning of
ff ff ff ff ff ff ff ff ff ff ff ff


orphan drugs unless they too are primary health care providers. Safety
ff ff ff ff ff ff ff ff ff ff ff


during pregnancy, use of a genericmedication, or classification of orphan
ff ff ff ff ff ff f ff ff ff ff


drugs are things the hospital client would be unable to answer but could
ff ff ff ff ff ff ff ff ff ff ff ff ff


be found in reference books if the nursing attendant wishes to research
ff ff ff ff ff ff ff ff ff ff ff ff


them.
ff