NUR 334 c
Pharm Exam 2 2026 – Pharmacology Questions,
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c Answers & Detailed Rationales
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📚 WHAT'S INCLUDED
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➢ NUR 334 Pharmacology Exam 2 study material
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➢ Pharmacology practice questions and answers
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➢ Detailed rationales explaining the reasoning behind answers
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, NUR 334 Pharm Exam 2 2026 – c c c c c c
c Pharmacology Questions, Answers & c c c
c Detailed Rationales c
1. What drug class does gentamicin belong to?
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A. Penicillins
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B. Fluoroquinolones
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C. Aminoglycosides
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D. Macrolides
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Correct Answer: C. Aminoglycosides
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Rationale: Gentamicin is a prototype drug of the aminoglycoside class,
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c which also includes streptomycin, amikacin, neomycin, and tobramycin.
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c Aminoglycosides are bactericidal antibiotics that inhibit protein
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c synthesis and are used for serious gram-negative infections.
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2. What is the indicated use of aminoglycosides? (Select all that apply)
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A. Treat severe infections of the abdomen and urinary tract
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B. Hospital-acquired pneumonia
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C. Bacteremia and endocarditis
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,D. Treatment of mild viral infections
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E. Serious gram-negative bacterial infections
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Correct Answer: A, B, C, E
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Rationale: Aminoglycosides are indicated for severe infections of the
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c abdomen and urinary tract, hospital-acquired pneumonia, bacteremia,
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c and endocarditis. They are also used for serious gram-negative bacterial
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c infections and infections caused by staphylococci when penicillins or
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c other less toxic drugs are contraindicated. They are NOT used for viral
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c infections.
3. Which antibiotics inhibit protein synthesis? (Select all that apply)
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A. Tetracyclines
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B. Macrolides
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C. Aminoglycosides
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D. Penicillins
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Correct Answer: A, B, C c c c c
Rationale: Tetracyclines, macrolides, and aminoglycosides all work by
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c inhibiting bacterial protein synthesis. Penicillins work by inhibiting cell
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c wall synthesis, not protein synthesis.
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, 4. Which of the following are pharmacokinetic properties of
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c gentamicin? (Select all that apply) c c c c
A. Well absorbed IM and IV
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B. Widely distributed in extracellular fluid
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C. Crosses the placenta
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D. Good penetration into CSF
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E. Greater than 90% renal excretion
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Correct Answer: A, B, C, E
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Rationale: Gentamicin is well absorbed IM and IV, widely distributed in
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c extracellular fluid, crosses the placenta, and small amounts enter breast
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c milk. However, it has POOR penetration into CSF. More than 90% is
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c excreted renally, with a half-life of 2-4 hours (longer in renal
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c impairment).
5. What drugs fall into the aminoglycoside drug class? (Select all that
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c apply)
A. Gentamicin
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B. Streptomycin
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C. Amikacin
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D. Neomycin
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E. Tobramycin
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