NUR 334
Pharm Exam 4 2026 | Exam Prep, Practice
Questions & Answer Rationales
📚 WHAT'S INCLUDED
➢ NUR 334 Pharmacology Exam 4 study material
➢ Pharmacology practice questions and answers
➢ Detailed rationales explaining the reasoning behind answers
,NUR 334 Pharm Exam 4 2026 | Exam Prep,
Practice Questions & Answer Rationales
1. What is the difference between H1 and H2 blockers?
A. H1 blockers reduce gastric acid; H2 blockers treat allergies
B. H1 blockers target histamine-1 receptors (allergic responses); H2
blockers target histamine-2 receptors on gastric parietal cells to reduce
acid secretion
C. H1 and H2 blockers are identical in function
D. H1 blockers are PPIs; H2 blockers are antacids
Answer: B
Rationale: H2 blockers specifically decrease stomach acid by blocking
histamine at H2 receptors on parietal cells. H1 blockers primarily treat
allergic symptoms.
2. Which medications fall into the H2 receptor antagonists category?
A. Omeprazole, lansoprazole, esomeprazole
B. Aluminum hydroxide, calcium carbonate, magnesium hydroxide
C. Famotidine, cimetidine, nizatidine
D. Bismuth, misoprostol, sucralfate
, Answer: C
Rationale: Famotidine, cimetidine, and nizatidine are the three major
H2 receptor antagonists that block histamine-2 receptors on gastric
parietal cells.
3. What is the mechanism of action (MOA) of proton pump inhibitors
(PPIs)?
A. Block histamine-2 receptors on parietal cells
B. Neutralize gastric acid by forming salt and water
C. Create a protective barrier over ulcers
D. Irreversibly inhibit the stomach's hydrogen-potassium ATPase proton
pump, causing profound and prolonged reduction of stomach acid
(MOST POTENT inhibitors)
Answer: D
Rationale: PPIs irreversibly block the H+/K+ ATPase pump in parietal
cells, providing the strongest acid suppression available.
4. What are PPIs used to treat?
A. Hypertension, angina, heart failure
B. GERD, ulcers, H. pylori infection
C. Constipation, diarrhea, IBS
D. Nausea, vomiting, motion sickness
Pharm Exam 4 2026 | Exam Prep, Practice
Questions & Answer Rationales
📚 WHAT'S INCLUDED
➢ NUR 334 Pharmacology Exam 4 study material
➢ Pharmacology practice questions and answers
➢ Detailed rationales explaining the reasoning behind answers
,NUR 334 Pharm Exam 4 2026 | Exam Prep,
Practice Questions & Answer Rationales
1. What is the difference between H1 and H2 blockers?
A. H1 blockers reduce gastric acid; H2 blockers treat allergies
B. H1 blockers target histamine-1 receptors (allergic responses); H2
blockers target histamine-2 receptors on gastric parietal cells to reduce
acid secretion
C. H1 and H2 blockers are identical in function
D. H1 blockers are PPIs; H2 blockers are antacids
Answer: B
Rationale: H2 blockers specifically decrease stomach acid by blocking
histamine at H2 receptors on parietal cells. H1 blockers primarily treat
allergic symptoms.
2. Which medications fall into the H2 receptor antagonists category?
A. Omeprazole, lansoprazole, esomeprazole
B. Aluminum hydroxide, calcium carbonate, magnesium hydroxide
C. Famotidine, cimetidine, nizatidine
D. Bismuth, misoprostol, sucralfate
, Answer: C
Rationale: Famotidine, cimetidine, and nizatidine are the three major
H2 receptor antagonists that block histamine-2 receptors on gastric
parietal cells.
3. What is the mechanism of action (MOA) of proton pump inhibitors
(PPIs)?
A. Block histamine-2 receptors on parietal cells
B. Neutralize gastric acid by forming salt and water
C. Create a protective barrier over ulcers
D. Irreversibly inhibit the stomach's hydrogen-potassium ATPase proton
pump, causing profound and prolonged reduction of stomach acid
(MOST POTENT inhibitors)
Answer: D
Rationale: PPIs irreversibly block the H+/K+ ATPase pump in parietal
cells, providing the strongest acid suppression available.
4. What are PPIs used to treat?
A. Hypertension, angina, heart failure
B. GERD, ulcers, H. pylori infection
C. Constipation, diarrhea, IBS
D. Nausea, vomiting, motion sickness
