Nur 318 exam 2 – UPDATED Questions with 100% Verified Answers
Nur 318 exam 2 – UPDATED Questions with 100%
Verified Answers
Section 1: Antidepressants, Serotonin, Novel (Q1–Q12)
Question & Answer
Q1 Anti depressant treatment
A -cyclic antidepressant -Enzyme inhibiting agents
Q2 cyclic Antidepressants types
A SSRIs SNRIs NDRIs
Q3 Novel antidepressant Noradrenergic/specific serotonergic agent
A mirtazapine
Q4 Novel antidepressant Serotonin-1A agonist/serotonin reuptake inhibitor
A Vilazodone
Q5 novel antidepressants Serotonin stimulator/ serotonin modulator
A vortioxetine
Q6 novel antidepressants Serotonin-2 antagonists/serotonin reuptake inhibitors
A trazodone and nefazodone.
Q7 cyclic Antidepressants Tricyclic antidepressants
A block the reuptake of both serotonin and norepinephrine -amitriptyline -desipramine
Q8 Reuptake-Inhibiting Antidepressants
A Cyclic Antidepressants
Q9 Important Issues Related to Antidepressant Use
A -Serotonin syndrome -Antidepressant apathy syndrome -Antidepressant withdrawal syndrome
-Antidepressant loss of effectiveness -Antidepressant-induced suicide
Q10 Side Effects of SSRI's
A -nausea -hyponatremia -excessive sweating -anticholinergic effects(sweating, dry mouth, sedation)
Q11 Selective Serotonin Reuptake Inhibitors (SSRIs)
A -first line for depression -black box suicide warning -risk of apathy syndrome
Q12 apathy syndrome
A persistent lack of motivation, interest, and emotional expression
Page 1 of 23
,Nur 318 exam 2 – UPDATED Questions with 100% Verified Answers
Section 2: Reuptake, Part, Inhibitors (Q13–Q24)
Question & Answer
Q13 Selective Serotonin Reuptake Inhibitors (SSRIs) med part 1
A Sertraline (Zoloft)
Q14 Selective Serotonin Reuptake Inhibitors (SSRIs) med part 2
A Fluoxetine (Prozac)
Q15 Selective Serotonin Reuptake Inhibitors (SSRIs) med part 3
A Escitalopram (Lexapro)
Q16 SSRIs side effects part 2
A Central nervous system effects -Headache -Dizziness -Tremors -Anxiety -Insomnia
Q17 Norepinephrine Dopamine Reuptake inhibitor (NDRI)
A -Only antidepressant with dopamine reuptake inhibition as a major mechanism of action. -Does not
affect serotonin systems. -Good SE profile. -Should not be given with drugs that increase dopamine
level.
Q18 NDRI Should not be given with drugs that increase dopamine level
A —
Q19 Serotonin-Norepinephrine Reuptake Inhibitors (SNRIs) meds part 1
A Duloxetine (Cymbalta)
Q20 Serotonin-Norepinephrine Reuptake Inhibitors (SNRIs) meds part 2
A Venlafaxine (Effexor) -cause increase bp
Q21 Serotonin-Norepinephrine Reuptake Inhibitors (SNRIs) meds part 3
A Desvenlafaxine (Pristiq)
Q22 Serotonin-Norepinephrine Reuptake Inhibitors (SNRIs) meds part 4
A Levomilnacipran (Fetzima)
Q23 Tricyclic Antidepressants (TCAs) Secondary amines
A Increase the availability of norepinephrine more than serotonin
Q24 Tricyclic Antidepressants (TCAs) tertiary
A Increase serotonin availability more than norepinephrine
Section 3: Maois, Tricyclic, Antidepressants (Q25–Q36)
Question & Answer
Q25 Tricyclic Antidepressants (TCAs) side effects Cardiac
A -tachycardia, hypertension, arrhythmias
Page 2 of 23
, Nur 318 exam 2 – UPDATED Questions with 100% Verified Answers
Question & Answer
Q26 Tricyclic Antidepressants (TCAs) side effects Anticholinergic
A -Dry mouth -Blurred vision -Constipation -Urinary dysfunction
Q27 Tricyclic Antidepressants (TCAs) Interactions
A -Drugs that depress the CNS(opioids) -Drugs that have anticholinergic properties (Benadryl) -Drugs
that stimulate the CNS -MAOIs (deaths have occurred)
Q28 Serotonin Syndrome occurs when comined with
A -Tryptophan -MAOIs -lithium -dextromethorphan -venlafaxine
Q29 Serotonin Syndrome what it looks like
A =hallucinations -shivering sweating -hypertension, tachycardia -ataxia (lack of coordination)
-twitching
Q30 Monoamine Oxidase Inhibitors (MAOIs) Nonselective irreversible inhibitors
A -Inhibit both variants of monoamine oxidase: MAO-A and MAO-B (the nonselective part) -"Stay on"
the enzyme until it dies and is replaced (the irreversible part)
Q31 Monoamine Oxidase Inhibitors (MAOIs) Selective MAOIs
A -Moclobemide inhibits only MAO-A (not in the United States) -Selegiline inhibits MAO-B (for
Parkinson's
Q32 Drug-Drug Interactions With MAOIs
A -Drug interactions that cause hypertension -Drug interactions that cause severe anticholinergic
responses -Drug interactions that cause profound CNS depression
Q33 Tyramine-Rich Foods to Avoid With MAOI's
A -alcohol -dairy products -avocado, bananas -salami, sausage -caffeinated, soy Sause
Q34 Lithium
A -Gold standard for bipolar disorder -Naturally occurring element -Neuroprotective treatment of
choice -Treatment and prophylaxis of manic phase
Q35 Lithium Pharmacological Effects
A -Inhibits release of norepinephrine, serotonin, and dopamine -casues there reuptake into
presynaptic terminals
Q36 Lithium Pharmacokinetics
A Peak blood levels: 1 to 3 hours -Absorption: GI tract -Excretion: kidneys -Plasma half-life: 24 hours
-Narrow therapeutic index
Page 3 of 23
Nur 318 exam 2 – UPDATED Questions with 100%
Verified Answers
Section 1: Antidepressants, Serotonin, Novel (Q1–Q12)
Question & Answer
Q1 Anti depressant treatment
A -cyclic antidepressant -Enzyme inhibiting agents
Q2 cyclic Antidepressants types
A SSRIs SNRIs NDRIs
Q3 Novel antidepressant Noradrenergic/specific serotonergic agent
A mirtazapine
Q4 Novel antidepressant Serotonin-1A agonist/serotonin reuptake inhibitor
A Vilazodone
Q5 novel antidepressants Serotonin stimulator/ serotonin modulator
A vortioxetine
Q6 novel antidepressants Serotonin-2 antagonists/serotonin reuptake inhibitors
A trazodone and nefazodone.
Q7 cyclic Antidepressants Tricyclic antidepressants
A block the reuptake of both serotonin and norepinephrine -amitriptyline -desipramine
Q8 Reuptake-Inhibiting Antidepressants
A Cyclic Antidepressants
Q9 Important Issues Related to Antidepressant Use
A -Serotonin syndrome -Antidepressant apathy syndrome -Antidepressant withdrawal syndrome
-Antidepressant loss of effectiveness -Antidepressant-induced suicide
Q10 Side Effects of SSRI's
A -nausea -hyponatremia -excessive sweating -anticholinergic effects(sweating, dry mouth, sedation)
Q11 Selective Serotonin Reuptake Inhibitors (SSRIs)
A -first line for depression -black box suicide warning -risk of apathy syndrome
Q12 apathy syndrome
A persistent lack of motivation, interest, and emotional expression
Page 1 of 23
,Nur 318 exam 2 – UPDATED Questions with 100% Verified Answers
Section 2: Reuptake, Part, Inhibitors (Q13–Q24)
Question & Answer
Q13 Selective Serotonin Reuptake Inhibitors (SSRIs) med part 1
A Sertraline (Zoloft)
Q14 Selective Serotonin Reuptake Inhibitors (SSRIs) med part 2
A Fluoxetine (Prozac)
Q15 Selective Serotonin Reuptake Inhibitors (SSRIs) med part 3
A Escitalopram (Lexapro)
Q16 SSRIs side effects part 2
A Central nervous system effects -Headache -Dizziness -Tremors -Anxiety -Insomnia
Q17 Norepinephrine Dopamine Reuptake inhibitor (NDRI)
A -Only antidepressant with dopamine reuptake inhibition as a major mechanism of action. -Does not
affect serotonin systems. -Good SE profile. -Should not be given with drugs that increase dopamine
level.
Q18 NDRI Should not be given with drugs that increase dopamine level
A —
Q19 Serotonin-Norepinephrine Reuptake Inhibitors (SNRIs) meds part 1
A Duloxetine (Cymbalta)
Q20 Serotonin-Norepinephrine Reuptake Inhibitors (SNRIs) meds part 2
A Venlafaxine (Effexor) -cause increase bp
Q21 Serotonin-Norepinephrine Reuptake Inhibitors (SNRIs) meds part 3
A Desvenlafaxine (Pristiq)
Q22 Serotonin-Norepinephrine Reuptake Inhibitors (SNRIs) meds part 4
A Levomilnacipran (Fetzima)
Q23 Tricyclic Antidepressants (TCAs) Secondary amines
A Increase the availability of norepinephrine more than serotonin
Q24 Tricyclic Antidepressants (TCAs) tertiary
A Increase serotonin availability more than norepinephrine
Section 3: Maois, Tricyclic, Antidepressants (Q25–Q36)
Question & Answer
Q25 Tricyclic Antidepressants (TCAs) side effects Cardiac
A -tachycardia, hypertension, arrhythmias
Page 2 of 23
, Nur 318 exam 2 – UPDATED Questions with 100% Verified Answers
Question & Answer
Q26 Tricyclic Antidepressants (TCAs) side effects Anticholinergic
A -Dry mouth -Blurred vision -Constipation -Urinary dysfunction
Q27 Tricyclic Antidepressants (TCAs) Interactions
A -Drugs that depress the CNS(opioids) -Drugs that have anticholinergic properties (Benadryl) -Drugs
that stimulate the CNS -MAOIs (deaths have occurred)
Q28 Serotonin Syndrome occurs when comined with
A -Tryptophan -MAOIs -lithium -dextromethorphan -venlafaxine
Q29 Serotonin Syndrome what it looks like
A =hallucinations -shivering sweating -hypertension, tachycardia -ataxia (lack of coordination)
-twitching
Q30 Monoamine Oxidase Inhibitors (MAOIs) Nonselective irreversible inhibitors
A -Inhibit both variants of monoamine oxidase: MAO-A and MAO-B (the nonselective part) -"Stay on"
the enzyme until it dies and is replaced (the irreversible part)
Q31 Monoamine Oxidase Inhibitors (MAOIs) Selective MAOIs
A -Moclobemide inhibits only MAO-A (not in the United States) -Selegiline inhibits MAO-B (for
Parkinson's
Q32 Drug-Drug Interactions With MAOIs
A -Drug interactions that cause hypertension -Drug interactions that cause severe anticholinergic
responses -Drug interactions that cause profound CNS depression
Q33 Tyramine-Rich Foods to Avoid With MAOI's
A -alcohol -dairy products -avocado, bananas -salami, sausage -caffeinated, soy Sause
Q34 Lithium
A -Gold standard for bipolar disorder -Naturally occurring element -Neuroprotective treatment of
choice -Treatment and prophylaxis of manic phase
Q35 Lithium Pharmacological Effects
A -Inhibits release of norepinephrine, serotonin, and dopamine -casues there reuptake into
presynaptic terminals
Q36 Lithium Pharmacokinetics
A Peak blood levels: 1 to 3 hours -Absorption: GI tract -Excretion: kidneys -Plasma half-life: 24 hours
-Narrow therapeutic index
Page 3 of 23
