BIOC 385 Metabolic Biochemistry Exam Final Test
Bank /Biochem 385 Exam Final With Actual Correct
Questions And Verified Detailed Answers| Currently
Testing Version | Already Graded A+|Newest |2026
2027 University Of Arizona
What enzyme catalyzes the following reaction in the first step of fatty acid synthesis?
fatty acyl-CoA synthetase
acetyl-CoA carboxylase
fatty acid synthase
fatty acyl-CoA dehydrogenase
acetyl-CoA carboxylase
What cofactor, common to carboxylase enzymes, is used by acetyl-CoA carboxylase?
NADPH
FAD
biotin
pyridoxal phosphate
biotin
What enzyme catalyzes the following fatty acid synthesis reaction?
fatty acid synthase
fatty acyl-CoA synthetase
fatty acyl-CoA dehydrogenase
acetyl-CoA carboxylase
fatty acid synthase
1|Page
,What are the different roles played the acyl carrier protein (ACP) and the ketoacyl
synthase (KS) domain during fatty acid synthesis?
The ACP carries the growing fatty acid chain more than the KS domain.
The KS domain holds the growing fatty acid chain, whereas the ACP delivers two carbon
fragments.
The KS domain associates with the fatty acid synthase enzyme, whereas the ACP does
not.
The ACP delivers two carbon fragments one at a time, whereas the KS domain passes
them on to the fatty acid.
The ACP carries the growing fatty acid chain more than the KS domain
The introduction of 14 CO2 into a cell actively synthesizing fatty acids results in 14C
labeled
malonyl-CoA.
acetyl-CoA.
acyl-CoA.
palmitate.
malonyl-CoA
Membrane phospholipids are synthesized in which cellular location?
cytoplasm
mitochondrial intermembrane space
mitochondrial matrix
smooth endoplasmic reticulum
smooth endoplasmic reticulum
The acetyl-CoA for fatty acid synthesis comes from the
breakdown of fats.
2|Page
,TCA cycle.
mitochondria via the citrate shuttle.
breakdown of cytoplasmic pyruvate.
mitochondria via the citrate shuttle
Which of the following causes inhibition of fatty acid synthesis?
increased insulin
increased AMP-activated protein kinase (AMPK)
decreased cytoplasmic acyl-CoA
increased cytoplasmic acetyl-CoA
increased AMP-activated protein kinase (AMPK)
What enzyme is activated by HDL to release cholesterol from the cell membranes of
peripheral tissues?
phosphatidylcholine esterase
HDL apolipase
cholesterol esterase
lecithin-cholesterol acyltransferase
lecithin-cholesterol acyltransferase
Which lipid is thought to give rise to the plaques that can clog arteries?
HDL
LDL
VLDL
chylomicrons
LDL
The 10 amino acids that animals need to take in through their diet are called the
__________ amino acids.
common
3|Page
, essential
optional
degradation
common
What are the four key enzymes in nitrogen fixation and assimilation in plants and
bacteria?
nitrogenase synthetase, glutamine complex, glutamate synthase, glutamate
dehydrogenase
nitrogenase complex, glutamine synthetase, glutamate synthase, glutamate
dehydrogenase
glutamine synthetase, glutamate synthase, glutamate dehydrogenase, glutamate
oxidase
nitrogenase complex, glutamine synthetase, glycine synthase, glutamine
dehydrogenase
nitrogenase complex, glutamine synthetase, glutamate synthase, glutamate
dehydrogenase
How does biological fixation convert nitrogen to ammonia?
by reducing nitrogen
by combining nitrogen with carbon
through the ATP-dependent process catalyzed by nitrogenase complex
through the NADH-dependent process catalyzed by glutamate dehydrogenase
through the ATP-dependent process catalyzed by nitrogenase complex
If plants and bacteria were unable to produce glutamate from ammonia, a possible
outcome would be that plants would
be able to produce more nucleotides.
no longer be able to produce other amino acids.
4|Page
Bank /Biochem 385 Exam Final With Actual Correct
Questions And Verified Detailed Answers| Currently
Testing Version | Already Graded A+|Newest |2026
2027 University Of Arizona
What enzyme catalyzes the following reaction in the first step of fatty acid synthesis?
fatty acyl-CoA synthetase
acetyl-CoA carboxylase
fatty acid synthase
fatty acyl-CoA dehydrogenase
acetyl-CoA carboxylase
What cofactor, common to carboxylase enzymes, is used by acetyl-CoA carboxylase?
NADPH
FAD
biotin
pyridoxal phosphate
biotin
What enzyme catalyzes the following fatty acid synthesis reaction?
fatty acid synthase
fatty acyl-CoA synthetase
fatty acyl-CoA dehydrogenase
acetyl-CoA carboxylase
fatty acid synthase
1|Page
,What are the different roles played the acyl carrier protein (ACP) and the ketoacyl
synthase (KS) domain during fatty acid synthesis?
The ACP carries the growing fatty acid chain more than the KS domain.
The KS domain holds the growing fatty acid chain, whereas the ACP delivers two carbon
fragments.
The KS domain associates with the fatty acid synthase enzyme, whereas the ACP does
not.
The ACP delivers two carbon fragments one at a time, whereas the KS domain passes
them on to the fatty acid.
The ACP carries the growing fatty acid chain more than the KS domain
The introduction of 14 CO2 into a cell actively synthesizing fatty acids results in 14C
labeled
malonyl-CoA.
acetyl-CoA.
acyl-CoA.
palmitate.
malonyl-CoA
Membrane phospholipids are synthesized in which cellular location?
cytoplasm
mitochondrial intermembrane space
mitochondrial matrix
smooth endoplasmic reticulum
smooth endoplasmic reticulum
The acetyl-CoA for fatty acid synthesis comes from the
breakdown of fats.
2|Page
,TCA cycle.
mitochondria via the citrate shuttle.
breakdown of cytoplasmic pyruvate.
mitochondria via the citrate shuttle
Which of the following causes inhibition of fatty acid synthesis?
increased insulin
increased AMP-activated protein kinase (AMPK)
decreased cytoplasmic acyl-CoA
increased cytoplasmic acetyl-CoA
increased AMP-activated protein kinase (AMPK)
What enzyme is activated by HDL to release cholesterol from the cell membranes of
peripheral tissues?
phosphatidylcholine esterase
HDL apolipase
cholesterol esterase
lecithin-cholesterol acyltransferase
lecithin-cholesterol acyltransferase
Which lipid is thought to give rise to the plaques that can clog arteries?
HDL
LDL
VLDL
chylomicrons
LDL
The 10 amino acids that animals need to take in through their diet are called the
__________ amino acids.
common
3|Page
, essential
optional
degradation
common
What are the four key enzymes in nitrogen fixation and assimilation in plants and
bacteria?
nitrogenase synthetase, glutamine complex, glutamate synthase, glutamate
dehydrogenase
nitrogenase complex, glutamine synthetase, glutamate synthase, glutamate
dehydrogenase
glutamine synthetase, glutamate synthase, glutamate dehydrogenase, glutamate
oxidase
nitrogenase complex, glutamine synthetase, glycine synthase, glutamine
dehydrogenase
nitrogenase complex, glutamine synthetase, glutamate synthase, glutamate
dehydrogenase
How does biological fixation convert nitrogen to ammonia?
by reducing nitrogen
by combining nitrogen with carbon
through the ATP-dependent process catalyzed by nitrogenase complex
through the NADH-dependent process catalyzed by glutamate dehydrogenase
through the ATP-dependent process catalyzed by nitrogenase complex
If plants and bacteria were unable to produce glutamate from ammonia, a possible
outcome would be that plants would
be able to produce more nucleotides.
no longer be able to produce other amino acids.
4|Page
