MICROBIOLOGY; EXAM 4; UAMS
QUESTIONS AND ANSWERS WITH
COMPLETE SOLUTIONS ALREADY
PASSED!!!
What are the four major structural drug classes included under the $\beta$-
lactam antibiotic family?
✔✔ Penicillins, Cephalosporins, Carbapenems, and Monobactams (all share a
core four-membered $\beta$-lactam ring structure).
Which specific antibiotic agents constitute the Natural Penicillins subclass?
✔✔ Penicillin G (intravenous/intramuscular) and Penicillin V (oral).
Which drugs belong to the Penicillinase-Resistant Penicillins (PRPs / Anti-
Staphylococcal Penicillins)?
✔✔ Methicillin, Oxacillin, and Nafcillin (along with Cloxacillin and
Dicloxacillin; designed to resist staphylococcal $\beta$-lactamase/penicillinase
cleaving).
Which sub-families make up the Extended-Spectrum Penicillins?
✔✔ Aminopenicillins (e.g., Ampicillin, Amoxicillin)
✔✔ Carboxypenicillins (e.g., Carbenicillin, Ticarcillin)
✔✔ Ureidopenicillins (e.g., Piperacillin, Mezlocillin)
Which drugs are included in the aminopenicillins?
Amoxicillin & ampicillin
Which drugs are included in the carboxypenicillins?
,Carbenicillin & ticarcillin
Which drugs are included in the ureidopenicillins?
Piperacillin, Azlocillin, & Mezlocillin
Which drugs are included in the carbapenems?
Imipenem
Dorpenem
Ertapenem
Meropenem
Which drug is included in the monobactam group?
Aztreonam
Antibiotics which inhibit cell wall synthesis include penicillins, carbapenems,
monobactam, __________, and ____________.
Cephems & vancomycin
Antibiotics which inhibit protein synthesis include Aminoglycosides, Macroslides,
Clindamycin, _______ & _______ .
Tetracycline and Chloramphenicol
, Which drugs inhibit DNA synthesis?
Metronidazole, Nitrofurantoin, Quinolones, & Sulfamides
Which drugs inhibit folic acid synthesis?
Sulfonamides & trimethoprim
Which drugs act on the cytoplasmic membrane?
Bacitracin & polymyxins
Which drug damages DNA and bacterial enzymes?
Nitrofurantoin
Name the 1st generation Cephalosporins
- Cefazolin
- Cephalothin
- Cephalexin
"Lin-thin-xin"
QUESTIONS AND ANSWERS WITH
COMPLETE SOLUTIONS ALREADY
PASSED!!!
What are the four major structural drug classes included under the $\beta$-
lactam antibiotic family?
✔✔ Penicillins, Cephalosporins, Carbapenems, and Monobactams (all share a
core four-membered $\beta$-lactam ring structure).
Which specific antibiotic agents constitute the Natural Penicillins subclass?
✔✔ Penicillin G (intravenous/intramuscular) and Penicillin V (oral).
Which drugs belong to the Penicillinase-Resistant Penicillins (PRPs / Anti-
Staphylococcal Penicillins)?
✔✔ Methicillin, Oxacillin, and Nafcillin (along with Cloxacillin and
Dicloxacillin; designed to resist staphylococcal $\beta$-lactamase/penicillinase
cleaving).
Which sub-families make up the Extended-Spectrum Penicillins?
✔✔ Aminopenicillins (e.g., Ampicillin, Amoxicillin)
✔✔ Carboxypenicillins (e.g., Carbenicillin, Ticarcillin)
✔✔ Ureidopenicillins (e.g., Piperacillin, Mezlocillin)
Which drugs are included in the aminopenicillins?
Amoxicillin & ampicillin
Which drugs are included in the carboxypenicillins?
,Carbenicillin & ticarcillin
Which drugs are included in the ureidopenicillins?
Piperacillin, Azlocillin, & Mezlocillin
Which drugs are included in the carbapenems?
Imipenem
Dorpenem
Ertapenem
Meropenem
Which drug is included in the monobactam group?
Aztreonam
Antibiotics which inhibit cell wall synthesis include penicillins, carbapenems,
monobactam, __________, and ____________.
Cephems & vancomycin
Antibiotics which inhibit protein synthesis include Aminoglycosides, Macroslides,
Clindamycin, _______ & _______ .
Tetracycline and Chloramphenicol
, Which drugs inhibit DNA synthesis?
Metronidazole, Nitrofurantoin, Quinolones, & Sulfamides
Which drugs inhibit folic acid synthesis?
Sulfonamides & trimethoprim
Which drugs act on the cytoplasmic membrane?
Bacitracin & polymyxins
Which drug damages DNA and bacterial enzymes?
Nitrofurantoin
Name the 1st generation Cephalosporins
- Cefazolin
- Cephalothin
- Cephalexin
"Lin-thin-xin"
