Oncology Emergencies – questions and
verified answers
Which of the following is not an oncology emergency
typically related to CNS tumors?
A) CSF leak
B) Spinal cord compression
C) Increased intracranial pressure
D) Superior Vena Cava Syndrome - ANS✔️✔️-D)
Superior Vena Cava Syndrome
The most serious hypercoagulable state occurring in
individuals with cancer is DIC. The most common cause
of this bleeding disorder is
A) neoplasms such as breast cancer or leukemia
B) infection
C) heparin drip
D) liver disease - ANS✔️✔️-B) infection
,Which of the following is not correct regarding the
pathophysiology of DIC?
A) Intrinsic pathway (factor VII) activated with damage
to endothelial lining of blood vessels and extrinsic
pathway (factor XII) activated with damage to
subendothelial tissue
B) The extrinsic and intrinsic pathway activations
result in clot formation and activation of coagulation
cascade
C) Fibrin clots are formed, accumulate in body's
circulatory system
D) Clots consume available platelets and coagulation
proteins. - ANS✔️✔️-A) Intrinsic pathway (factor VII)
activated with damage to endothelial lining of blood
vessels and extrinsic pathway (factor XII) activated
with damage to subendothelial tissue
Extrinsic pathway (factor VII) activated with damage to
endothelial lining of blood vessels and intrinsic
pathway (factor XII) activated with damage to
subendothelial tissue
Which of the following is the most common cause of
DIC?
A) sepsis and/or severe infection
B) vascular abnormalities
C) severe allergic reactions
D) severe immunologic reactions
,E) malignancy, both solid tumors and leukemia -
ANS✔️✔️-A) sepsis and/or severe infection
Which of the following lab results would you not expect
to see in DIC?
A) platelet count of 8,000
B) prothrombin time 30 seconds
C) fibrinogen 50-100/100 mL
D) platelet count of 150,000 - ANS✔️✔️-D) platelet count
of 150,000
Which of the following would not be a used
management for DIC?
A) Transfusions of platelets, fresh frozen plasma (FFP),
cryoprecipitate, and whole blood
B) Use of anticoagulants like heparin or low molecular
weight heparin
C) Use of fibrinolytic agents- epsilon-aminocaproic acid,
tranexamic acid
D) Anticoagulant factor concentrates (e.g., recombinant
human-activated protein C - ANS✔️✔️-A) Transfusions of
platelets, fresh frozen plasma (FFP), cryoprecipitate,
and whole blood
Would not use whole blood
What is a disorder of platelet aggregation, in which
thrombosis of the microvasculature may occur?
A) Disseminated Intravascular Coagulation
, B) Thrombotic Thrombocytopenic Purpura (TTP)
l.. l.. l.. l.. l..
C) Thromboembolism
l..
D) Pulmonary Embolism - ANS✔️✔️-B) Thrombotic
l.. l.. l.. l.. l.. l..
Thrombocytopenic Purpura (TTP) l.. l..
With lack of ADAMTS13 causes ULVWFs to be broken
l.. l.. l.. l.. l.. l.. l.. l.. l..
down and, instead, continue to stick to the endothelium,
l.. l.. l.. l.. l.. l.. l.. l.. l..
collecting platelets that pass by, which results in l.. l.. l.. l.. l.. l.. l.. l..
formation of thrombi. This correctly describes which l.. l.. l.. l.. l.. l.. l..
metabolic emergency? l..
A) Disseminated Intravascular Coagulation
l.. l.. l.. l..
B) Thrombotic Thrombocytopenic Purpura (TTP)
l.. l.. l.. l.. l..
C) Thromboembolism
l..
D) Pulmonary Embolism - ANS✔️✔️-B) Thrombotic
l.. l.. l.. l.. l.. l..
Thrombocytopenic Purpura (TTP) l.. l..
What is the most common cancer cause of SIADH?
l.. l.. l.. l.. l.. l.. l.. l..
A) Leukemia
l..
B) Multiple Myeloma
l.. l..
C) Lung cancer
l.. l..
D) Breast cancer - ANS✔️✔️-C) Lung cancer
l.. l.. l.. l.. l.. l..
Which of the following is treatment that would not be used
l.. l.. l.. l.. l.. l.. l.. l.. l.. l..
for mild SIADH, but instead for moderate SIADH?
l.. l.. l.. l.. l.. l.. l.. l..
A) Fluid restriction to 1000 mL/day; water intake should
l.. l.. l.. l.. l.. l.. l.. l.. l..
not exceed the urine output
l.. l.. l.. l..
B) Review of current medications for underlying cause
l.. l.. l.. l.. l.. l.. l..
C) Neurologic assessment
l.. l..
verified answers
Which of the following is not an oncology emergency
typically related to CNS tumors?
A) CSF leak
B) Spinal cord compression
C) Increased intracranial pressure
D) Superior Vena Cava Syndrome - ANS✔️✔️-D)
Superior Vena Cava Syndrome
The most serious hypercoagulable state occurring in
individuals with cancer is DIC. The most common cause
of this bleeding disorder is
A) neoplasms such as breast cancer or leukemia
B) infection
C) heparin drip
D) liver disease - ANS✔️✔️-B) infection
,Which of the following is not correct regarding the
pathophysiology of DIC?
A) Intrinsic pathway (factor VII) activated with damage
to endothelial lining of blood vessels and extrinsic
pathway (factor XII) activated with damage to
subendothelial tissue
B) The extrinsic and intrinsic pathway activations
result in clot formation and activation of coagulation
cascade
C) Fibrin clots are formed, accumulate in body's
circulatory system
D) Clots consume available platelets and coagulation
proteins. - ANS✔️✔️-A) Intrinsic pathway (factor VII)
activated with damage to endothelial lining of blood
vessels and extrinsic pathway (factor XII) activated
with damage to subendothelial tissue
Extrinsic pathway (factor VII) activated with damage to
endothelial lining of blood vessels and intrinsic
pathway (factor XII) activated with damage to
subendothelial tissue
Which of the following is the most common cause of
DIC?
A) sepsis and/or severe infection
B) vascular abnormalities
C) severe allergic reactions
D) severe immunologic reactions
,E) malignancy, both solid tumors and leukemia -
ANS✔️✔️-A) sepsis and/or severe infection
Which of the following lab results would you not expect
to see in DIC?
A) platelet count of 8,000
B) prothrombin time 30 seconds
C) fibrinogen 50-100/100 mL
D) platelet count of 150,000 - ANS✔️✔️-D) platelet count
of 150,000
Which of the following would not be a used
management for DIC?
A) Transfusions of platelets, fresh frozen plasma (FFP),
cryoprecipitate, and whole blood
B) Use of anticoagulants like heparin or low molecular
weight heparin
C) Use of fibrinolytic agents- epsilon-aminocaproic acid,
tranexamic acid
D) Anticoagulant factor concentrates (e.g., recombinant
human-activated protein C - ANS✔️✔️-A) Transfusions of
platelets, fresh frozen plasma (FFP), cryoprecipitate,
and whole blood
Would not use whole blood
What is a disorder of platelet aggregation, in which
thrombosis of the microvasculature may occur?
A) Disseminated Intravascular Coagulation
, B) Thrombotic Thrombocytopenic Purpura (TTP)
l.. l.. l.. l.. l..
C) Thromboembolism
l..
D) Pulmonary Embolism - ANS✔️✔️-B) Thrombotic
l.. l.. l.. l.. l.. l..
Thrombocytopenic Purpura (TTP) l.. l..
With lack of ADAMTS13 causes ULVWFs to be broken
l.. l.. l.. l.. l.. l.. l.. l.. l..
down and, instead, continue to stick to the endothelium,
l.. l.. l.. l.. l.. l.. l.. l.. l..
collecting platelets that pass by, which results in l.. l.. l.. l.. l.. l.. l.. l..
formation of thrombi. This correctly describes which l.. l.. l.. l.. l.. l.. l..
metabolic emergency? l..
A) Disseminated Intravascular Coagulation
l.. l.. l.. l..
B) Thrombotic Thrombocytopenic Purpura (TTP)
l.. l.. l.. l.. l..
C) Thromboembolism
l..
D) Pulmonary Embolism - ANS✔️✔️-B) Thrombotic
l.. l.. l.. l.. l.. l..
Thrombocytopenic Purpura (TTP) l.. l..
What is the most common cancer cause of SIADH?
l.. l.. l.. l.. l.. l.. l.. l..
A) Leukemia
l..
B) Multiple Myeloma
l.. l..
C) Lung cancer
l.. l..
D) Breast cancer - ANS✔️✔️-C) Lung cancer
l.. l.. l.. l.. l.. l..
Which of the following is treatment that would not be used
l.. l.. l.. l.. l.. l.. l.. l.. l.. l..
for mild SIADH, but instead for moderate SIADH?
l.. l.. l.. l.. l.. l.. l.. l..
A) Fluid restriction to 1000 mL/day; water intake should
l.. l.. l.. l.. l.. l.. l.. l.. l..
not exceed the urine output
l.. l.. l.. l..
B) Review of current medications for underlying cause
l.. l.. l.. l.. l.. l.. l..
C) Neurologic assessment
l.. l..
