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NR 565/ NR565 ADVANCED PHARMACOLOGY FINAL EXAM |
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1. Which medication should be used in the treatment of tuberculosis in pregnancy?
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• A. Ethambutol xx
• B. Pyridoxine
xx
• C. Rifapentine
xx
• D. Rifabutin xx
Correct Answer: D. Rifabutin x x x x x x
Rationale: Rifabutin is considered safe for use in pregnancy for the treatment of
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xx tuberculosis. Ethambutol is also used, but rifabutin is specifically noted in the exam as the
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xx correct answer. Pyridoxine (vitamin B6) is given as adjunctive therapy to prevent
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xx neuropathy from isoniazid, not as a primary anti-TB drug. Rifapentine is generally avoided
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xx in pregnancy due to insufficient safety data.
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Traveler'sDiarrhea xx
2. A couple celebrating their 30th wedding anniversary are given a trip to Peru to visit
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xx Machu Picchu. Because of past experiences while traveling, they ask their doctor to
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xx prescribe an agent in case they experience diarrhea. Which of the following drugs would be
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xx effective?
• A. Omeprazole xx
• B. Loperamide
xx
• C. Famotidine
xx
• D. Lubiprostonexx
,NR565AdvancedPharmacology
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Correct Answer: B. Loperamide x x x x x x
Rationale: Loperamide is an antidiarrheal agent that slows intestinal motility and is x x x x x x x x x x x x x x x x x x x x x x
effective for symptomatic relief of traveler's diarrhea. Omeprazole and famotidine are acid-
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suppressing agents, not antidiarrheals. Lubiprostone is a laxative used for constipation and xx xx xx xx xx xx xx xx xx xx xx
xx IBS-C.
3. Neena is planning missionary work in a region with poor drinking water. She is given
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xx a prescription for ciprofloxacin to take with her. Which of the following instructions are
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xx most important to discuss with Neena?
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• A. Start ciprofloxacin 1 week before traveling.
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• B. Take 1 tablet of ciprofloxacin with each meal while living in areas with inadequate water
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xx maintenance.
• C. Use the drug if symptoms develop and are severe or do not improve in a few days.
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• D. Combine the antibiotic with an antidiarrheal medication, such as loperamide.
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Correct Answer: C. Use the drug if symptoms develop and are severe or do not improve in
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xx a few days.
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Rationale: Ciprofloxacin is not taken prophylactically for traveler's diarrhea. It should
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be used if symptoms develop and are severe or persist. Starting it a week before travel
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xx not recommended. Taking it with every meal is not appropriate. Combining an antibiotic
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xx with loperamide should be done with caution and only under specific guidance.
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