NRSG 2350 Pharm Exam 2 EXPECTED QUESTIONS WITH
VERIFIED ANSWERS
Question 1.
epoetin alfa (Epogen, Procrit)
ANSWER
Treats anemia associated with renal failure and AIDS
Decreases need for blood transfusions in patients undergoing surgery
Question 2.
Darbepoetin alfa (Aranesp)
ANSWER
Treats anemia associated with chronic kidney disease including patients on dialysis
Question 3.
ferrous sulfate (Feosol)
ANSWER
Treatment of iron deficiency anemia
Actions: elevated serum iron + converts to hemoglobin or stored for eventual conversion to
usable form of iron
ORAL
AE: GI, anorexia, NVD, CNS toxicity leading to coma, death with OD
CONSIDER: iron absorption DECREASES if taken with antacids, tetracyclines (if needed take 2
hrs apart - same with ciprofloaxin)
Question 4.
Ferrous Gluconate (Fergon)
ANSWER
iron supplement
,Question 5.
Iron Dextran (Venofer)
ANSWER
Treatment of iron deficiency anemia (parenteral)
Risks: associated with severe anaphylactic reactions, local irritations, staining of tissues
*monitor patient during infusion*
Question 6.
Hydroxyurea (Droxia)
ANSWER
treats SICKLE CELL ANEMIA: decreases need for blood transfusions
Actions: increases fetal hemoglobin production in the bone marrow and dilutes formation of
abnormal hemoglobin S
ORAL
AE: dizzy, HA, Rash, Anorexia, Bone marrow depression, Cancer
Question 7.
Heparin
ANSWER
PREVENTS CLOTS
Prevention & treatment of venous thrombosis and PE, DIC
Actions: inhibits thrombus and clot production by blocking conversion of prothrombin to
thrombin and fibrinogen to fibrin
DOES NOT DISSOLVE CLOTS
IV/SUB Q
AE: loss of hair, chills, bruising, fever, osteoporosis, suppression of renal function w long term
use
Question 8.
Antiplatelet drugs
ANSWER
PROTOTYPE: ASPIRIN
Plavix, aspirin, anagrelide
FOR: CAD, maintenance of arterial/venous grafts, prevents cerebrovascular occlusion,
during/post MI for thrombolytic effect
Inhibit platelet aggregation and adhesion
ASPIRIN: inhibits synthesis of thromboxane A + decreases platelet aggregation
, PLAVIX: inhibits binding of ATP (inhibits platelet aggregation)
ANAGRELIDE: blocks production of platelets in bone marrow (treats thrombocythemia)
CI: bleeding d/o, uncontrolled HTN, recent surgery
CAUTION: monitor bleeding, combo with other anticoag/antiplatelet drugs, monitor for
salicylate poisoning
Question 9.
Heparin antidote
ANSWER
protamine sulfate
Question 10.
Warfarin (Coumadin)
ANSWER
Anticoagulant
Prevention/manage DVT, PE, associated with atrial fib & prosthetic heart valves
Prevents synthesis of VIT K by bacteria in GI tract
Inhibits production of clotting factors: II, VII, IX, X (Vit K dependent factors)
Effects: after 2-3 days
ORAL
CI: pregnancy, renal/hepatic disease, all others per heparin
Monitor bleeding, frequent labs to assess therapeutic range, NO GRAPEFRUIT!!!!
Question 11.
Warfarin (Coumadin) Antidote
ANSWER
Phytonadione (vitamin K)
VERIFIED ANSWERS
Question 1.
epoetin alfa (Epogen, Procrit)
ANSWER
Treats anemia associated with renal failure and AIDS
Decreases need for blood transfusions in patients undergoing surgery
Question 2.
Darbepoetin alfa (Aranesp)
ANSWER
Treats anemia associated with chronic kidney disease including patients on dialysis
Question 3.
ferrous sulfate (Feosol)
ANSWER
Treatment of iron deficiency anemia
Actions: elevated serum iron + converts to hemoglobin or stored for eventual conversion to
usable form of iron
ORAL
AE: GI, anorexia, NVD, CNS toxicity leading to coma, death with OD
CONSIDER: iron absorption DECREASES if taken with antacids, tetracyclines (if needed take 2
hrs apart - same with ciprofloaxin)
Question 4.
Ferrous Gluconate (Fergon)
ANSWER
iron supplement
,Question 5.
Iron Dextran (Venofer)
ANSWER
Treatment of iron deficiency anemia (parenteral)
Risks: associated with severe anaphylactic reactions, local irritations, staining of tissues
*monitor patient during infusion*
Question 6.
Hydroxyurea (Droxia)
ANSWER
treats SICKLE CELL ANEMIA: decreases need for blood transfusions
Actions: increases fetal hemoglobin production in the bone marrow and dilutes formation of
abnormal hemoglobin S
ORAL
AE: dizzy, HA, Rash, Anorexia, Bone marrow depression, Cancer
Question 7.
Heparin
ANSWER
PREVENTS CLOTS
Prevention & treatment of venous thrombosis and PE, DIC
Actions: inhibits thrombus and clot production by blocking conversion of prothrombin to
thrombin and fibrinogen to fibrin
DOES NOT DISSOLVE CLOTS
IV/SUB Q
AE: loss of hair, chills, bruising, fever, osteoporosis, suppression of renal function w long term
use
Question 8.
Antiplatelet drugs
ANSWER
PROTOTYPE: ASPIRIN
Plavix, aspirin, anagrelide
FOR: CAD, maintenance of arterial/venous grafts, prevents cerebrovascular occlusion,
during/post MI for thrombolytic effect
Inhibit platelet aggregation and adhesion
ASPIRIN: inhibits synthesis of thromboxane A + decreases platelet aggregation
, PLAVIX: inhibits binding of ATP (inhibits platelet aggregation)
ANAGRELIDE: blocks production of platelets in bone marrow (treats thrombocythemia)
CI: bleeding d/o, uncontrolled HTN, recent surgery
CAUTION: monitor bleeding, combo with other anticoag/antiplatelet drugs, monitor for
salicylate poisoning
Question 9.
Heparin antidote
ANSWER
protamine sulfate
Question 10.
Warfarin (Coumadin)
ANSWER
Anticoagulant
Prevention/manage DVT, PE, associated with atrial fib & prosthetic heart valves
Prevents synthesis of VIT K by bacteria in GI tract
Inhibits production of clotting factors: II, VII, IX, X (Vit K dependent factors)
Effects: after 2-3 days
ORAL
CI: pregnancy, renal/hepatic disease, all others per heparin
Monitor bleeding, frequent labs to assess therapeutic range, NO GRAPEFRUIT!!!!
Question 11.
Warfarin (Coumadin) Antidote
ANSWER
Phytonadione (vitamin K)
