Test Bank –
Pathophysiology for Advanced Practice,
By Workman,Clochesy
1st edition
,TABLE OF CONTENTS
PART I: FOUNDATIONAL PHYSIOLOGIC CONCEPTS
I. The Cell
1. Cellular Biology, Regulation, and Control Mechanisms
2. Cellular and Tissue Physiology
3. Bioenergetics and Body Metabolism
4. Body Fluid Homeostasis
II. Genetics and Genomics
5. Basic Genetics
6. Patterns of Inheritance, Mitochondrial Inheritance, Epigenetic and Selected Associated Disorders
III. Inflammation, Immunity, Infection, and Cancer Biology
7. Innate Immunity and Inflammation
8. Adaptive Immunity
9. Infectious Processes and Body Responses
10. Abnormal Cell Growth and Cancer Biology
PART II: PATHOPHYSIOLOGY OF DISORDERS WITHIN SPECIFIC BODY SYSTEMS
OXYGENATION AND PERFUSION
IV. Cardiovascular System
11. Review of Cardiovascular Development, Structure, and Function
12. Vascular Disorders
13. Cardiac Disorders
14. Congenital Heart Disease Across the Lifespan
15. Shock and Multiple Organ Dysfunction Syndrome
V. Pulmonary System
16. Review of Pulmonary Structure, Development, and Function
17. Congenital, Obstructive, and Restrictive Pulmonary Disorders
18. Infectious Pulmonary Disorders and Lung Cancer
VI. Renal-Urinary System
19. Review of Renal System Structure, Development, and Function
20. Urinary Tract Disorders
21. Kidney Disorders
VII. Hematologic and Lymphatic System
22. Chapter 22. Review of Hematologic System Development, Structure, and Function
23. Chapter 23. Hematologic and Lymphatic System Disorders
SENSATION, MOBILITY, AND REGULATION
VIII. Nervous System
24. Review of Nervous System Development, Structure, and Function
25. Central Nervous System Disorders
26. Peripheral Nervous System Disorder
27. Disorders of the Special Senses
28. Mental Health Disorders
IX. Musculoskeletal System
29. Review of Musculoskeletal Development, Structure, and Function
30. Muscle and Tendon Disorders
,31. Bone and Joint Disorders
X. Endocrine System
32. Review of Endocrine Structure, Function, and Interactions
33. Disorders of the Hypothalamus, Pituitary Glands, and Adrenal Glands
34. Disorders of the Thyroid Gland and the Parathyroid Glands
35. Glycemic Control and Diabetes Mellitus
PROTECTION, NUTRITION, AND REPRODUCTION
XI. Disorders of Immunity
36. Disorders of Reduced Immune Function
37. Hypersensitivity and Autoimmune Disorders
XII. Integumentary System
38. Review of Integumentary Development, Structure, and Function
39. Integumentary System Disorder
XIII. Digestive System
40. Review of Gastrointestinal Development, Structure, and Function
41. Disorders of the Mouth, Throat, Esophagus, and Stomach
42. Disorders of the Small Intestine, Large Intestine, Pancreas, and Hepatobiliary System
XIV. Reproductive Systems
43. Review of Reproductive System Development, Structure, Function, and Sex Chromosome
Abnormalities
44. Common Disorders of the Female Reproductive System
45. Male Reproductive Disorders
46. Sexually Transmitted Infections
47. Physiology and Pathophysiology of the Breast
, PART I: FOUNDATIONAL PHYSIOLOGIC CONCEPTS
SECTION I: THE CELL
Chapter 1: Cellular Biology, Regulation, and Control Mechanisms
1. A nurse practitioner is reviewing the cell cycle with a student. During which
phase of the cell cycle does DNA replication occur?
A. G1 phase
B. S phase
C. G2 phase
D. M phase
Answer: B
Rationale: DNA synthesis (replication) occurs during the S (synthesis) phase of
interphase. G1 is cell growth, G2 is preparation for mitosis, and M is mitosis itself.
2. Which cellular structure is primarily responsible for the production of
adenosine triphosphate (ATP) through oxidative phosphorylation?
A. Rough endoplasmic reticulum
B. Golgi apparatus
C. Mitochondria
D. Lysosome
Answer: C
Rationale: Mitochondria are the primary site of ATP production via the electron
transport chain and oxidative phosphorylation.
3. A patient's lab results reveal impaired protein synthesis. Which organelle is
most directly involved in the translation of mRNA into proteins?
A. Smooth endoplasmic reticulum
B. Ribosome
C. Peroxisome
D. Centriole
Answer: B
Rationale: Ribosomes (free and bound to the rough ER) are the sites of protein
synthesis, translating mRNA into polypeptide chains.
Pathophysiology for Advanced Practice,
By Workman,Clochesy
1st edition
,TABLE OF CONTENTS
PART I: FOUNDATIONAL PHYSIOLOGIC CONCEPTS
I. The Cell
1. Cellular Biology, Regulation, and Control Mechanisms
2. Cellular and Tissue Physiology
3. Bioenergetics and Body Metabolism
4. Body Fluid Homeostasis
II. Genetics and Genomics
5. Basic Genetics
6. Patterns of Inheritance, Mitochondrial Inheritance, Epigenetic and Selected Associated Disorders
III. Inflammation, Immunity, Infection, and Cancer Biology
7. Innate Immunity and Inflammation
8. Adaptive Immunity
9. Infectious Processes and Body Responses
10. Abnormal Cell Growth and Cancer Biology
PART II: PATHOPHYSIOLOGY OF DISORDERS WITHIN SPECIFIC BODY SYSTEMS
OXYGENATION AND PERFUSION
IV. Cardiovascular System
11. Review of Cardiovascular Development, Structure, and Function
12. Vascular Disorders
13. Cardiac Disorders
14. Congenital Heart Disease Across the Lifespan
15. Shock and Multiple Organ Dysfunction Syndrome
V. Pulmonary System
16. Review of Pulmonary Structure, Development, and Function
17. Congenital, Obstructive, and Restrictive Pulmonary Disorders
18. Infectious Pulmonary Disorders and Lung Cancer
VI. Renal-Urinary System
19. Review of Renal System Structure, Development, and Function
20. Urinary Tract Disorders
21. Kidney Disorders
VII. Hematologic and Lymphatic System
22. Chapter 22. Review of Hematologic System Development, Structure, and Function
23. Chapter 23. Hematologic and Lymphatic System Disorders
SENSATION, MOBILITY, AND REGULATION
VIII. Nervous System
24. Review of Nervous System Development, Structure, and Function
25. Central Nervous System Disorders
26. Peripheral Nervous System Disorder
27. Disorders of the Special Senses
28. Mental Health Disorders
IX. Musculoskeletal System
29. Review of Musculoskeletal Development, Structure, and Function
30. Muscle and Tendon Disorders
,31. Bone and Joint Disorders
X. Endocrine System
32. Review of Endocrine Structure, Function, and Interactions
33. Disorders of the Hypothalamus, Pituitary Glands, and Adrenal Glands
34. Disorders of the Thyroid Gland and the Parathyroid Glands
35. Glycemic Control and Diabetes Mellitus
PROTECTION, NUTRITION, AND REPRODUCTION
XI. Disorders of Immunity
36. Disorders of Reduced Immune Function
37. Hypersensitivity and Autoimmune Disorders
XII. Integumentary System
38. Review of Integumentary Development, Structure, and Function
39. Integumentary System Disorder
XIII. Digestive System
40. Review of Gastrointestinal Development, Structure, and Function
41. Disorders of the Mouth, Throat, Esophagus, and Stomach
42. Disorders of the Small Intestine, Large Intestine, Pancreas, and Hepatobiliary System
XIV. Reproductive Systems
43. Review of Reproductive System Development, Structure, Function, and Sex Chromosome
Abnormalities
44. Common Disorders of the Female Reproductive System
45. Male Reproductive Disorders
46. Sexually Transmitted Infections
47. Physiology and Pathophysiology of the Breast
, PART I: FOUNDATIONAL PHYSIOLOGIC CONCEPTS
SECTION I: THE CELL
Chapter 1: Cellular Biology, Regulation, and Control Mechanisms
1. A nurse practitioner is reviewing the cell cycle with a student. During which
phase of the cell cycle does DNA replication occur?
A. G1 phase
B. S phase
C. G2 phase
D. M phase
Answer: B
Rationale: DNA synthesis (replication) occurs during the S (synthesis) phase of
interphase. G1 is cell growth, G2 is preparation for mitosis, and M is mitosis itself.
2. Which cellular structure is primarily responsible for the production of
adenosine triphosphate (ATP) through oxidative phosphorylation?
A. Rough endoplasmic reticulum
B. Golgi apparatus
C. Mitochondria
D. Lysosome
Answer: C
Rationale: Mitochondria are the primary site of ATP production via the electron
transport chain and oxidative phosphorylation.
3. A patient's lab results reveal impaired protein synthesis. Which organelle is
most directly involved in the translation of mRNA into proteins?
A. Smooth endoplasmic reticulum
B. Ribosome
C. Peroxisome
D. Centriole
Answer: B
Rationale: Ribosomes (free and bound to the rough ER) are the sites of protein
synthesis, translating mRNA into polypeptide chains.
