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Exam (elaborations)

MICR 221 final exam questions with correct answers

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MICR 221 final exam questions with correct answers

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MICR 221 final exam questions with correct
answers


what is an HERV and what does it represent - CORRECT ANSWER✔✔-
| | | | | | | | | | |



human endogenous retroviruses; represent footprints of ancient
| | | | | | |



germline retroviral infections | |




viruses do not encode information for - CORRECT ANSWER✔✔-energy
| | | | | | | | |



production, ribosomes, tRNAs (some exceptions), lipid membrane
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synthesis


each plaque represents - CORRECT ANSWER✔✔-one single "successful"
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viral infection
|




virion - CORRECT ANSWER✔✔-mature infectious virus particle
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capsid - CORRECT ANSWER✔✔-protein shell that encloses and protects
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the viral nucleic acid
| | |




capsomere - CORRECT ANSWER✔✔-subunit of a viral capsid
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,core - CORRECT ANSWER✔✔-internal part of the virus particle
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consisting of nucleic acid and closely associated proteins
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nucleocapsid - CORRECT ANSWER✔✔-structure formed by capsid | | | | | | |



containing the nucleic acid or core | | | | |




envelope - CORRECT ANSWER✔✔-viral membrane consisting of a lipid
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bilayer containing spike proteins
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spike proteins - CORRECT ANSWER✔✔-viral glycoproteins projecting
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from the envelope
| |




two general mechanisms for viruses to package their genomes (capsids)
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- CORRECT ANSWER✔✔-helical capsids and capsids with icosahedral
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symetry


what type of naked helical viruses have never been found - CORRECT
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ANSWER✔✔-animal viruses |




what type of nucleic acid is found in enveloped animal viruses with
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helical capsids - CORRECT ANSWER✔✔-RNA only, never DNA
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why are helical capsids "open structures" - CORRECT ANSWER✔✔-the
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ends aren't sealed
| |

, icosahedrons have how many vertices and what shape are their
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subunits - CORRECT ANSWER✔✔-20 vertices, triangle subunits
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how does genetic economy apply to icosahedral capsids - CORRECT
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ANSWER✔✔-the same proteins are used to create the triangle subunits
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how do non-enveloped viruses typically exit the cell - CORRECT
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ANSWER✔✔-lysis


how do enveloped viruses typically acquire their envelope - CORRECT
| | | | | | | | | |



ANSWER✔✔-budding through a membrane in the host cell into some | | | | | | | | | |



extra-cytoplasmic compartment |




3 roles of glycoproteins - CORRECT ANSWER✔✔-1. entry and host range
| | | | | | | | | |



|determination 2. assembly and egress 3. evasion from vertebrate
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immune system |




what two things does Gag polyprotein bind to? why? - CORRECT
| | | | | | | | | | |



ANSWER✔✔-binds the retrovirus RNA genome and the tail of the | | | | | | | | | |



glycoprotein in the membrane of the cell; does this to drag RNA to the
| | | | | | | | | | | | | |



surface of the cell and a budding reaction occurs to form an enveloped
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virus

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