Practicode I Exam Questions and Answers Study Guide

Practicode I (1–350) Exam Questions and Answers
Study Guide 3 versions

This comprehensive study resource is a premier test bank designed for medical coders
preparing for the American Academy of Professional Coders (AAPC) Practicode Set
(Cases 1–350). It features realistic redacted medical records, 100% verified CPT, ICD-
10-CM, and HCPCS code selections, and step-by-step documentation rationales.
Reviewing these real-world outpatient, radiology, and surgical cases ensures optimal
sequencing accuracy and RVU ordering protocols to sharpen your practical coding
skills and accelerate the removal of your apprentice designation.

Question 1:
A patient undergoes a screening colonoscopy that reveals a polyp, which is removed by
snare. What is the correct coding?
A. 45378
B. 45385
C. 45380
D. 45384

Answer: B. 45385
Rationale: When a screening colonoscopy becomes diagnostic due to the removal of a
polyp, the diagnostic code 45385 is reported. The screening code is not reported separately
when the procedure becomes diagnostic .




Question 2:
A patient undergoes a screening flexible sigmoidoscopy. What is the correct CPT code?
A. 45330
B. 45331
C. 45333
D. 45338

Answer: A. 45330
Rationale: CPT 45330 is for sigmoidoscopy, flexible; diagnostic, with or without collection
of specimen(s) by brushing or washing. For screening, modifier -33 is appended .

,Question 3:
A patient undergoes a diagnostic colonoscopy with biopsy. What is the correct CPT
code?
A. 45378
B. 45380
C. 45384
D. 45385

Answer: B. 45380
Rationale: CPT 45380 is for colonoscopy, flexible; with biopsy, single or multiple. 45378 is
diagnostic colonoscopy without biopsy .




Question 4:
A patient undergoes an upper GI endoscopy with biopsy. What is the correct CPT code?
A. 43235
B. 43239
C. 43234
D. 43248

Answer: B. 43239
Rationale: CPT 43239 is for esophagogastroduodenoscopy, flexible, transoral; with biopsy,
single or multiple. 43235 is diagnostic EGD without biopsy .




Question 5:
A patient undergoes a colonoscopy with removal of a polyp by hot forceps. What is the
correct CPT code?
A. 45384
B. 45385
C. 45380
D. 45378

Answer: A. 45384
Rationale: CPT 45384 is for colonoscopy with removal of tumor(s), polyp(s), or other
lesion(s) by hot biopsy forceps. 45385 is for snare technique .

,Question 6:
A patient undergoes a percutaneous liver biopsy. What is the correct CPT code?
A. 47000
B. 47001
C. 47100
D. 47370

Answer: A. 47000
Rationale: CPT 47000 is for biopsy of liver, percutaneous needle. 47001 is for biopsy of
liver, percutaneous needle with imaging guidance .




Question 7:
A patient undergoes a paracentesis. What is the correct CPT code?
A. 49080
B. 49081
C. 49082
D. 49083

Answer: A. 49080
Rationale: CPT 49080 is for peritoneocentesis, abdominal paracentesis, or peritoneal
lavage (diagnostic or therapeutic); initial. 49081 is for subsequent .




Question 8:
A patient undergoes a thoracentesis. What is the correct CPT code?
A. 32421
B. 32422
C. 32554
D. 32555

Answer: A. 32421
Rationale: CPT 32421 is for thoracentesis, puncture of pleural cavity for aspiration, initial
or subsequent. 32422 is for thoracentesis with insertion of tube .

, Question 9:
A patient undergoes a bone marrow biopsy. What is the correct CPT code?
A. 38220
B. 38221
C. 38222
D. 38230

Answer: B. 38221
Rationale: CPT 38221 is for bone marrow biopsy, needle or trocar. 38220 is for bone
marrow aspiration .




Question 10:
A patient undergoes a lumbar puncture for diagnostic purposes. What is the correct CPT
code?
A. 62270
B. 62272
C. 62273
D. 62280

Answer: A. 62270
Rationale: CPT 62270 is for spinal puncture, lumbar, diagnostic. 62272 is for therapeutic .




Question 11:
A patient undergoes a nerve conduction study. What is the correct CPT code?
A. 95907
B. 95908
C. 95909
D. 95910

Answer: A. 95907
Rationale: CPT 95907 is for nerve conduction studies; 1-2 studies. 95908 is for 3-4 studies,
95909 is for 5-6 studies .