CHAPTER 5: ABO AND H BLOOD GROUP SYSTEMS AND SECRETOR
STATUS Questions with Correct Solutions
Question:
1. 1. Given the following ABO typing results, what is a potential conclusion for these results?
ABO Testing Results Patient Red Cells with Patient Serum with Reagent Red Cells Anti-A
Anti-B A1 B 4+ 4+ 1+ 0
a. expected results for a group O individual
b. expected results for a group AB individual
c. discrepant results; patient has A antigen on red cells with anti-A in serum
d. discrepant results; patient has B antigen on red cells with no anti-B in serum
Answer:
c. discrepant results; patient has A antigen on red cells with anti-A in serum
Question:
2. 2. What are the gene products of the A and B genes?
a. glycolipids
b. glycoproteins
c. oligosaccharides
d. transferase enzymes
Answer:
d. transferase enzymes
Question:
3. For questions 3 through 5, use the following ABO typing results: ABO Testing Results
Patient Red Cells with Patient Serum with Reagent Red Cells Anti-A Anti-B A1 B 0 0 4+ 4+
3. What is the ABO interpretation?
a. group O
b. group A
c. group B
d. group AB
Answer:
a. group O
Question:
4. 4. What ABO phenotypes would be compatible if the patient required a transfusion of
RBCs?
a. group AB, O, A, or B
b. group O or B
c. group AB or O
d. only group O
,Answer:
d. only group O
Question:
5. 5. What ABO phenotypes would be compatible if the patient required a transfusion of fresh
frozen plasma?
a. group AB, O, A, or B
b. group O or B
c. group AB or O
d. only group O
Answer:
a. group AB, O, A, or B
Question:
6. 6. What term describes using known sources of reagent antisera (known antibodies) to
detect ABO antigens on a patient's red cells?
a. Rh typing
b. reverse grouping
c. direct antiglobulin test
d. forward grouping
Answer:
d. forward grouping
Question:
7. 7. Which result is discrepant if the red cell typing shown in the following chart is correct?
ABO Testing Results Patient Red Cells with Patient Serum with Reagent Red Cells Anti-A
Anti-B A1 B 0 4+ 0 0
a. negative reaction with group B cells
b. positive reaction with anti-B
c. negative reaction with group A1 cells
d. no discrepancies in these results
Answer:
c. negative reaction with group A1 cells
Question:
8. 8. What ABO antibody is expected in this patient serum based on the following
information? Patient Red Cells with Anti-A Anti-B 0 0
a. anti-B
b. anti-A
c. anti-A and anti-B
d. none
, Answer:
c. anti-A and anti-B
Question:
9. 9. According to Landsteiner's rule, if a patient has no ABO antibodies after serum testing,
what ABO antigens are present on the patient's red cells?
a. A
b. B
c. both A and B
d. none
Answer:
c. both A and B
Question:
10. 10. Select the ABO phenotypes, in order from most frequent to least frequent, that occur
in whites:
a. A, B, O, AB
b. O, A, B, AB
c. B, A, AB, O
d. AB, O, B, A
Answer:
b. O, A, B, AB
Question:
11. 11. Which of the following statements is true about ABO antibody production?
a. ABO antibodies are present in newborns
b. ABO titers remain at constant levels throughout life
c. ABO antibodies are stimulated by bacteria and other environmental factors
d. All of these statements are true
Answer:
c. ABO antibodies are stimulated by bacteria and other environmental factors
Question:
12. 12. What immunoglobulin class is primarily associated with ABO antibodies?
a. IgA
b. IgG
c. IgE
d. IgM
Answer:
d. IgM
STATUS Questions with Correct Solutions
Question:
1. 1. Given the following ABO typing results, what is a potential conclusion for these results?
ABO Testing Results Patient Red Cells with Patient Serum with Reagent Red Cells Anti-A
Anti-B A1 B 4+ 4+ 1+ 0
a. expected results for a group O individual
b. expected results for a group AB individual
c. discrepant results; patient has A antigen on red cells with anti-A in serum
d. discrepant results; patient has B antigen on red cells with no anti-B in serum
Answer:
c. discrepant results; patient has A antigen on red cells with anti-A in serum
Question:
2. 2. What are the gene products of the A and B genes?
a. glycolipids
b. glycoproteins
c. oligosaccharides
d. transferase enzymes
Answer:
d. transferase enzymes
Question:
3. For questions 3 through 5, use the following ABO typing results: ABO Testing Results
Patient Red Cells with Patient Serum with Reagent Red Cells Anti-A Anti-B A1 B 0 0 4+ 4+
3. What is the ABO interpretation?
a. group O
b. group A
c. group B
d. group AB
Answer:
a. group O
Question:
4. 4. What ABO phenotypes would be compatible if the patient required a transfusion of
RBCs?
a. group AB, O, A, or B
b. group O or B
c. group AB or O
d. only group O
,Answer:
d. only group O
Question:
5. 5. What ABO phenotypes would be compatible if the patient required a transfusion of fresh
frozen plasma?
a. group AB, O, A, or B
b. group O or B
c. group AB or O
d. only group O
Answer:
a. group AB, O, A, or B
Question:
6. 6. What term describes using known sources of reagent antisera (known antibodies) to
detect ABO antigens on a patient's red cells?
a. Rh typing
b. reverse grouping
c. direct antiglobulin test
d. forward grouping
Answer:
d. forward grouping
Question:
7. 7. Which result is discrepant if the red cell typing shown in the following chart is correct?
ABO Testing Results Patient Red Cells with Patient Serum with Reagent Red Cells Anti-A
Anti-B A1 B 0 4+ 0 0
a. negative reaction with group B cells
b. positive reaction with anti-B
c. negative reaction with group A1 cells
d. no discrepancies in these results
Answer:
c. negative reaction with group A1 cells
Question:
8. 8. What ABO antibody is expected in this patient serum based on the following
information? Patient Red Cells with Anti-A Anti-B 0 0
a. anti-B
b. anti-A
c. anti-A and anti-B
d. none
, Answer:
c. anti-A and anti-B
Question:
9. 9. According to Landsteiner's rule, if a patient has no ABO antibodies after serum testing,
what ABO antigens are present on the patient's red cells?
a. A
b. B
c. both A and B
d. none
Answer:
c. both A and B
Question:
10. 10. Select the ABO phenotypes, in order from most frequent to least frequent, that occur
in whites:
a. A, B, O, AB
b. O, A, B, AB
c. B, A, AB, O
d. AB, O, B, A
Answer:
b. O, A, B, AB
Question:
11. 11. Which of the following statements is true about ABO antibody production?
a. ABO antibodies are present in newborns
b. ABO titers remain at constant levels throughout life
c. ABO antibodies are stimulated by bacteria and other environmental factors
d. All of these statements are true
Answer:
c. ABO antibodies are stimulated by bacteria and other environmental factors
Question:
12. 12. What immunoglobulin class is primarily associated with ABO antibodies?
a. IgA
b. IgG
c. IgE
d. IgM
Answer:
d. IgM