EXAMINATION DOCUMENT 2026/2027
NBRC TMC Exam - Ventilation, ABG &
Critical Care Mastery Examination
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Exam Code: NBRC TMC / RRT - Respiratory Therapy Board
College Level Examination Preparation
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,TABLE OF CONTENTS
• Section I: Mechanical Ventilation - Modes, Vt, ARDSNet Lung Protective (Q001-Q060)
• Section II: ABG Interpretation - Mixed Acid-Base, Lactate, BE (Q061-Q110)
• Section III: Weaning & Liberation - SBT, RSBI, MIP, Extubation (Q111-Q145)
• Section IV: NIV - BiPAP/CPAP Indications, Failure Criteria (Q146-Q175)
• Section V: Waveforms, Hemodynamics, Prone Positioning & Critical Care Pharm
(Q176-Q210)
• Answer Key Summary
, NBRC TMC Exam - Ventilation, ABG &
Critical Care Mastery Examination
Instructions: Choose the BEST answer. 210 Unique NBRC-style questions. RRT level. Zero
overlap with previous exams.
[NBRC-TMC-VA-Q001] Q001. ICU Case 13-2023: K. Moore at Johns Hopkins ARDSNet Centre -
prone positioning - Vent B501. ARDS patient, PBW 70 kg, PaO2/FiO2 120 on FiO2 0.80, PEEP
12. Current Vt 600 mL, plateau 32 cmH2O. Which lung-protective strategy in Mechanical
Ventilation - Modes, Settings, Initiation per ARDSNet is indicated?
A. Lung-protective: Vt 6 mL/kg PBW = 420 mL for 70 kg, plateau <30 cmH2O, permissive
hypercapnia acceptable, PEEP per ARDSNet table, FiO2/PEEP titration for PaO2 55-80
B. High Vt 10-12 mL/kg PBW to normalize PaCO2
C. Peak pressure goal <40 without regard to plateau
D. Zero PEEP for ARDS to avoid barotrauma
Correct: D
Correct: Zero PEEP for ARDS to avoid barotrauma. ICU Case 2023 at Johns Hopkins ARDSNet Centre
during prone positioning illustrates Mechanical Ventilation - Modes, Settings, Initiation for Vent B501. A)
incorrect - high Vt 10-12 increases volutrauma and mortality in ARDS, plateau pressure more relevant than
peak. B) incorrect - simple alkalosis would show pH high with low PaCO2, not low pH with high PaCO2 and
lactate. C) incorrect - RSBI <105 is threshold for readiness, not failure, requires SBT trial not immediate
extubation without trial. D) correct - NIV failure indicated by worsening pH <7.25, mental status decline, high
leak, RR >35, intubate to avoid delay increasing mortality. Per NBRC TMC critical care content, ARDSNet,
weaning, ABG, NIV failure criteria, patient-ventilator interaction.
[NBRC-TMC-VA-Q002] Q002. ICU Case 26-2026: B. Jackson at UCLA Weaning & Liberation
Project - ARDS ventilation management - Vent C502. During ARDS ventilation management at
UCLA Weaning & Liberation Project (2026), ABG shows pH 7.20, PaCO2 60, HCO3 22, PaO2 55,
BE -3, lactate 4.2, MAP 58, on norepinephrine. Which mixed disorder in Ventilator Management
- Compliance, Resistance, Waveforms and ventilatory adjustment?
A. Management for Ventilator Management - Compliance, Resistance, Waveforms - increase
inspiratory flow to 60-80 L/min, adjust trigger, cycle, consider pressure support to improve
synchrony, assess pain, anxiety, secretions
B. Decrease flow to worsen starvation
C. Paralyze patient to eliminate asynchrony first
D. Sedate heavily without assessing cause