TEST BANK
l7
Introduction to Genetic Analysis
l7 l7 l7
Anthony J.F. Griffiths, John Doebley, Catherine Peichel, and David A.
l7 l7 l7 l7 l7 l7 l7 l7 l7
Wassarman
l 7
12th Edition
l7
,Table of Contents
l7 l7
Chapter l7 01 l 7 The Genetics Revolution
l7 l 7 1
Chapter l 7 02 l 7 Single Gene Inheritance
l7 l 7 6
Chapter l7 03 l7 Independent Assortment of Genes l7 l7 l7 26
Chapter l7 04 l 7 Mapping Eukaryote Chromosomes by Recombination
l 7 l7 l 7 l 7 43
Chapter l 7 05 l 7 Gene Interaction
l 7 63
Chapter l7 06 l 7 The Genetics of Bacteria and Their Viruses
l7 l 7 l 7 l 7 l 7 l 7 84
Chapter l7 07 l 7 DNA Structure and Replication
l7 l 7 l 7 104
Chapter l 7 08 l 7 RNA Transcription Processing and Decay
l 7 l 7 l 7 l 7 117
Chapter l7 09 l 7 Proteins and Their Synthesis
l7 l 7 l 7 130
Chapter 10 Gene Isolation and Manipulation
l 7 l 7 l 7 l 7 l 7 141
Chapter l 7 11 l 7 Regulation of Gene Expression in Bacteria and Their Viruses
l 7 l 7 l 7 l 7 l 7 l 7 l 7 l 7 160
Chapter l7 12 l 7 Regulation of Gene Expression in Eukaryotes
l 7 l 7 l 7 l 7 l 7 175
Chapter l 7 13 l 7 The Genetic Control of Development
l7 l7 l 7 l 7 184
Chapter l 7 14 l 7 Genomes and Genomics l 7 l 7 192
Chapter l7 15 l 7 DNA Damage Repair and Recombination
l 7 l7 l 7 l 7 197
Chapter l7 16l7 The Dynamic Genome Transposable Elements
l7 l7 l7 l7 216
Chapter l7 17 l7 Large Scale Chromosomal Changes
l7 l7 l7 225
Chapter 18 Population Genetics
l 7 l 7 l 7 243
Chapter 19 The Inheritance of Complex Traits
l 7 l 7 l 7 l 7 l7 l 7 258
Chapter 20 Evolution of Genes and Traits
l 7 l 7 l 7 l 7 l 7 l 7 270
, Test Bank - Introduction to Genetic
l 7 l 7 l 7 l 7 l 7 l 7 Analysis, 12th Edition (Griffiths, 2021)
l 7 l 7 l 7 l 7
Chapter 01: The Genetics Revolution
l7 l7 l7 l 7
1. The early 1900s was an important period for genetics due to which of the following major events?
l7 l7 l7 l7 l7 l7 l7 l7 l7 l7 l7 l7 l7 l7 l7 l7
a. the rediscovery of Gregor Mendel's scientific findings
l7 l7 l7 l7 l7 l7
b. Watson and Crick solving the structure of DNA l7 l7 l7 l7 l7 l7 l7
c. Walter Sutton and Theodore Boveri hypothesizing that chromosomes are the hereditary elements
l7 l7 l7 l7 l7 l7 l7 l7 l7 l7 l7
d. the rediscovery of Gregor Mendel's scientific findings and Walter Sutton and Theodore
l7 l7 l7 l7 l7 l7 l7 l7 l7 l7 l7
Boveri hypothesizing that chromosomes are the hereditary elements
l 7 l 7 l 7 l 7 l 7 l 7 l 7 l 7
e. All of the answer options are correct.
l7 l7 l7 l7 l7 l7
ANSWER: e l 7 l 7
2. A sample of normal double-stranded DNA was found to have a guanine content of 18%.
l 7 l7 l7 l 7 l 7 l7 l 7 l7 l 7 l7 l7 l7 l7 l7
l7What is the expected proportion of adenine?
l 7 l7 l7 l7 l7 l7
a. 9%
b. 32%
c. 36%
d. 68%
e. 82%
ANSWER: b l 7 l 7
3. In one strand of DNA, the nucleotide sequence is 5'-ATGC-3'. The complementary sequence
l7 l7 l7 l 7 l 7 l7 l7 l7 l7 l7 l7 l7
l7in the other strand must be
l7 l7 l7 l7 l7
a. 3'-ATGC-5'.
b. 3'-TACG-5'.
c. 5'-ATCG-3'.
d. 5'-CGTA-3'.
e. 5'-TACG-3'.
ANSWER: b l 7 l 7
4. How many different DNA molecules that are eight-nucleotide-pairs long are theoretically possible?
l7 l7 l7 l7 l7 l7 l7 l7 l7 l7 l7
a. 24
b. 32
c. 64
d. 256
e. 65,536
ANSWER: e l 7 l 7
5. Which of the following is/are TRUE about genes?
l7 l7 l7 l7 l7 l7 l7
a. Genes are located on chromosomes. l7 l7 l7 l7
b. Genes come in variants known as alleles. l7 l7 l7 l7 l7 l7
c. Genes usually encode protein products. l7 l7 l7 l7
d. All of the answer options are correct.
l7 l7 l7 l7 l7 l7
e. None of the answer options is correct.
l7 l7 l7 l7 l7 l7
ANSWER: d l 7 l 7
1| P a
l7 l 7 l 7
g e
, Test Bank - Introduction to Genetic
l 7 l 7 l 7 l 7 l 7 l 7 Analysis, 12th Edition (Griffiths, 2021) l 7 l 7 l 7 l 7
6. Wild cats (Felis silvestris) and common mice (Mus musculus) are diploid. In wild cats,
l 7 l 7 l 7 l 7 l 7 l 7 l 7 l 7 l 7 l 7 l 7 l 7 l 7
2n = 38, while in common mice, 2n = 40. Based on this information, we can conclude that
l 7 l 7 l 7 l7 l7 l 7 l 7 l 7 l 7 l 7 l 7 l 7 l 7 l7 l 7 l 7 l 7 l 7
wild-cat cells have
l 7 l 7 l 7
a. less DNA than common-mouse cells.
l7 l7 l7 l7
b. smaller genomes than common-mouse cells. l7 l7 l7 l7
c. fewer DNA molecules than common-mouse cells.
l7 l7 l7 l7 l7
d. fewer genes than common-mouse cells.
l7 l7 l7 l7
e. fewer sets of chromosomes than common-mouse cells.
l7 l7 l7 l7 l7 l7
ANSWER: c l 7 l 7
7. Which of the following is a component of DNA?
l7 l7 l7 l7 l7 l7 l7 l7
a. alanine
b. arginine
c. cysteine
d. guanine
e. tyrosine
ANSWER: d l 7 l 7
8. Which of the following is/are TRUE of the DNA structure solved by Watson and Crick?
l7 l7 l7 l7 l7 l7 l7 l7 l7 l7 l7 l7 l7 l7
a. It is a double-helical structure.
l7 l7 l7 l7
b. Sugar–phosphate backbone is always toward the outside of the DNA. l7 l7 l7 l7 l7 l7 l7 l7 l7
c. There are two hydrogen bonds between A and T and three hydrogen bonds between C and G.
l7 l7 l7 l 7 l7 l7 l7 l7 l7 l7 l7 l7 l7 l7 l7 l7
d. There are four types of nitrogenous bases.
l7 l7 l7 l7 l7 l7
e. All of the answer options are correct.
l7 l7 l7 l7 l7 l7
ANSWER: e l 7 l 7
9. Which of the following is a CORRECT representation of the central dogma?
l7 l7 l7 l7 l7 l7 l7 l7 l7 l7 l7
a. RNA → DNA → protein l7 l7 l7 l7
b. protein → DNA → RNA l7 l7 l7 l7
c. DNA → RNA → protein l7 l7 l7 l7
d. DNA → protein → DNA l7 l7 l7 l7
e. None of the answer options is correct.
l7 l7 l7 l7 l7 l7
ANSWER: c l 7 l 7
10. You have come across a dog (named Cindy) that does not have a tail. Interestingly, all
l 7 l 7 l 7 l 7 l 7 l 7 l 7 l 7 l 7 l 7 l 7 l 7 l 7 l 7 l 7
the puppies produced by this dog don't have a tail. If the lack of tail is caused by a genetic
l 7 l 7 l7 l 7 l 7 l 7 l 7 l 7 l 7 l 7 l 7 l 7 l 7 l 7 l 7 l 7 l 7 l 7 l 7 l 7
mutation, where has this mutation most likely taken place?
l 7 l 7 l 7 l 7 l7 l7 l7 l7 l7
a. in Cindy's gametes
l7 l7
b. in the cells that should normally have given rise to Cindy's tail
l7 l7 l7 l7 l7 l7 l7 l7 l7 l7 l7
c. in the cells that should normally have given rise to Cindy's and her puppies' tails
l7 l7 l7 l7 l7 l7 l7 l7 l7 l7 l7 l7 l7 l7
d. in all of Cindy's cells (including her gametes)
l7 l7 l7 l7 l7 l7 l7
e. in a gamete of one of Cindy's parents
l7 l7 l7 l7 l7 l7 l7
ANSWER: a l 7 l 7
11. Which of the following features makes a species suitable as a model organism?
l7 l7 l7 l7 l7 l7 l7 l7 l7 l7 l7 l7
2| P a
l7 l 7 l 7
g e
l7
Introduction to Genetic Analysis
l7 l7 l7
Anthony J.F. Griffiths, John Doebley, Catherine Peichel, and David A.
l7 l7 l7 l7 l7 l7 l7 l7 l7
Wassarman
l 7
12th Edition
l7
,Table of Contents
l7 l7
Chapter l7 01 l 7 The Genetics Revolution
l7 l 7 1
Chapter l 7 02 l 7 Single Gene Inheritance
l7 l 7 6
Chapter l7 03 l7 Independent Assortment of Genes l7 l7 l7 26
Chapter l7 04 l 7 Mapping Eukaryote Chromosomes by Recombination
l 7 l7 l 7 l 7 43
Chapter l 7 05 l 7 Gene Interaction
l 7 63
Chapter l7 06 l 7 The Genetics of Bacteria and Their Viruses
l7 l 7 l 7 l 7 l 7 l 7 84
Chapter l7 07 l 7 DNA Structure and Replication
l7 l 7 l 7 104
Chapter l 7 08 l 7 RNA Transcription Processing and Decay
l 7 l 7 l 7 l 7 117
Chapter l7 09 l 7 Proteins and Their Synthesis
l7 l 7 l 7 130
Chapter 10 Gene Isolation and Manipulation
l 7 l 7 l 7 l 7 l 7 141
Chapter l 7 11 l 7 Regulation of Gene Expression in Bacteria and Their Viruses
l 7 l 7 l 7 l 7 l 7 l 7 l 7 l 7 160
Chapter l7 12 l 7 Regulation of Gene Expression in Eukaryotes
l 7 l 7 l 7 l 7 l 7 175
Chapter l 7 13 l 7 The Genetic Control of Development
l7 l7 l 7 l 7 184
Chapter l 7 14 l 7 Genomes and Genomics l 7 l 7 192
Chapter l7 15 l 7 DNA Damage Repair and Recombination
l 7 l7 l 7 l 7 197
Chapter l7 16l7 The Dynamic Genome Transposable Elements
l7 l7 l7 l7 216
Chapter l7 17 l7 Large Scale Chromosomal Changes
l7 l7 l7 225
Chapter 18 Population Genetics
l 7 l 7 l 7 243
Chapter 19 The Inheritance of Complex Traits
l 7 l 7 l 7 l 7 l7 l 7 258
Chapter 20 Evolution of Genes and Traits
l 7 l 7 l 7 l 7 l 7 l 7 270
, Test Bank - Introduction to Genetic
l 7 l 7 l 7 l 7 l 7 l 7 Analysis, 12th Edition (Griffiths, 2021)
l 7 l 7 l 7 l 7
Chapter 01: The Genetics Revolution
l7 l7 l7 l 7
1. The early 1900s was an important period for genetics due to which of the following major events?
l7 l7 l7 l7 l7 l7 l7 l7 l7 l7 l7 l7 l7 l7 l7 l7
a. the rediscovery of Gregor Mendel's scientific findings
l7 l7 l7 l7 l7 l7
b. Watson and Crick solving the structure of DNA l7 l7 l7 l7 l7 l7 l7
c. Walter Sutton and Theodore Boveri hypothesizing that chromosomes are the hereditary elements
l7 l7 l7 l7 l7 l7 l7 l7 l7 l7 l7
d. the rediscovery of Gregor Mendel's scientific findings and Walter Sutton and Theodore
l7 l7 l7 l7 l7 l7 l7 l7 l7 l7 l7
Boveri hypothesizing that chromosomes are the hereditary elements
l 7 l 7 l 7 l 7 l 7 l 7 l 7 l 7
e. All of the answer options are correct.
l7 l7 l7 l7 l7 l7
ANSWER: e l 7 l 7
2. A sample of normal double-stranded DNA was found to have a guanine content of 18%.
l 7 l7 l7 l 7 l 7 l7 l 7 l7 l 7 l7 l7 l7 l7 l7
l7What is the expected proportion of adenine?
l 7 l7 l7 l7 l7 l7
a. 9%
b. 32%
c. 36%
d. 68%
e. 82%
ANSWER: b l 7 l 7
3. In one strand of DNA, the nucleotide sequence is 5'-ATGC-3'. The complementary sequence
l7 l7 l7 l 7 l 7 l7 l7 l7 l7 l7 l7 l7
l7in the other strand must be
l7 l7 l7 l7 l7
a. 3'-ATGC-5'.
b. 3'-TACG-5'.
c. 5'-ATCG-3'.
d. 5'-CGTA-3'.
e. 5'-TACG-3'.
ANSWER: b l 7 l 7
4. How many different DNA molecules that are eight-nucleotide-pairs long are theoretically possible?
l7 l7 l7 l7 l7 l7 l7 l7 l7 l7 l7
a. 24
b. 32
c. 64
d. 256
e. 65,536
ANSWER: e l 7 l 7
5. Which of the following is/are TRUE about genes?
l7 l7 l7 l7 l7 l7 l7
a. Genes are located on chromosomes. l7 l7 l7 l7
b. Genes come in variants known as alleles. l7 l7 l7 l7 l7 l7
c. Genes usually encode protein products. l7 l7 l7 l7
d. All of the answer options are correct.
l7 l7 l7 l7 l7 l7
e. None of the answer options is correct.
l7 l7 l7 l7 l7 l7
ANSWER: d l 7 l 7
1| P a
l7 l 7 l 7
g e
, Test Bank - Introduction to Genetic
l 7 l 7 l 7 l 7 l 7 l 7 Analysis, 12th Edition (Griffiths, 2021) l 7 l 7 l 7 l 7
6. Wild cats (Felis silvestris) and common mice (Mus musculus) are diploid. In wild cats,
l 7 l 7 l 7 l 7 l 7 l 7 l 7 l 7 l 7 l 7 l 7 l 7 l 7
2n = 38, while in common mice, 2n = 40. Based on this information, we can conclude that
l 7 l 7 l 7 l7 l7 l 7 l 7 l 7 l 7 l 7 l 7 l 7 l 7 l7 l 7 l 7 l 7 l 7
wild-cat cells have
l 7 l 7 l 7
a. less DNA than common-mouse cells.
l7 l7 l7 l7
b. smaller genomes than common-mouse cells. l7 l7 l7 l7
c. fewer DNA molecules than common-mouse cells.
l7 l7 l7 l7 l7
d. fewer genes than common-mouse cells.
l7 l7 l7 l7
e. fewer sets of chromosomes than common-mouse cells.
l7 l7 l7 l7 l7 l7
ANSWER: c l 7 l 7
7. Which of the following is a component of DNA?
l7 l7 l7 l7 l7 l7 l7 l7
a. alanine
b. arginine
c. cysteine
d. guanine
e. tyrosine
ANSWER: d l 7 l 7
8. Which of the following is/are TRUE of the DNA structure solved by Watson and Crick?
l7 l7 l7 l7 l7 l7 l7 l7 l7 l7 l7 l7 l7 l7
a. It is a double-helical structure.
l7 l7 l7 l7
b. Sugar–phosphate backbone is always toward the outside of the DNA. l7 l7 l7 l7 l7 l7 l7 l7 l7
c. There are two hydrogen bonds between A and T and three hydrogen bonds between C and G.
l7 l7 l7 l 7 l7 l7 l7 l7 l7 l7 l7 l7 l7 l7 l7 l7
d. There are four types of nitrogenous bases.
l7 l7 l7 l7 l7 l7
e. All of the answer options are correct.
l7 l7 l7 l7 l7 l7
ANSWER: e l 7 l 7
9. Which of the following is a CORRECT representation of the central dogma?
l7 l7 l7 l7 l7 l7 l7 l7 l7 l7 l7
a. RNA → DNA → protein l7 l7 l7 l7
b. protein → DNA → RNA l7 l7 l7 l7
c. DNA → RNA → protein l7 l7 l7 l7
d. DNA → protein → DNA l7 l7 l7 l7
e. None of the answer options is correct.
l7 l7 l7 l7 l7 l7
ANSWER: c l 7 l 7
10. You have come across a dog (named Cindy) that does not have a tail. Interestingly, all
l 7 l 7 l 7 l 7 l 7 l 7 l 7 l 7 l 7 l 7 l 7 l 7 l 7 l 7 l 7
the puppies produced by this dog don't have a tail. If the lack of tail is caused by a genetic
l 7 l 7 l7 l 7 l 7 l 7 l 7 l 7 l 7 l 7 l 7 l 7 l 7 l 7 l 7 l 7 l 7 l 7 l 7 l 7
mutation, where has this mutation most likely taken place?
l 7 l 7 l 7 l 7 l7 l7 l7 l7 l7
a. in Cindy's gametes
l7 l7
b. in the cells that should normally have given rise to Cindy's tail
l7 l7 l7 l7 l7 l7 l7 l7 l7 l7 l7
c. in the cells that should normally have given rise to Cindy's and her puppies' tails
l7 l7 l7 l7 l7 l7 l7 l7 l7 l7 l7 l7 l7 l7
d. in all of Cindy's cells (including her gametes)
l7 l7 l7 l7 l7 l7 l7
e. in a gamete of one of Cindy's parents
l7 l7 l7 l7 l7 l7 l7
ANSWER: a l 7 l 7
11. Which of the following features makes a species suitable as a model organism?
l7 l7 l7 l7 l7 l7 l7 l7 l7 l7 l7 l7
2| P a
l7 l 7 l 7
g e
