ATI CAPSTONE PHARMACOLOGY 1 & 2
Comprehensive Test Bank & Exam Preparation Guide
Exam: ATI Capstone Pharmacology Assessment 1 & 2
Format: NGNAligned Multiple Choice & Clinical Judgment Questions
Total Questions: 300
Cognitive Levels: Recall, Comprehension, Application, Analysis, Clinical Judgment
Table of Contents
Exam Overview & Instructions (Page 2)
Section A: Medication Administration & Safety (Page 3)
Questions 1–50
The Rights of Medication Administration, HighAlert Medications, LASA Drugs, Medication
Reconciliation, Error Prevention & Reporting, Dosage Calculations
Section B: Pharmacokinetics & Pharmacodynamics (Page 7)
Questions 51–80
Absorption, Distribution, Metabolism, Excretion, Therapeutic Index, Drug Interactions
Section C: Cardiovascular & Respiratory Medications (Page 10)
Questions 81–140
Antihypertensives, Anticoagulants, Antiplatelets, Digoxin, Diuretics, Bronchodilators,
Corticosteroids, Leukotriene Modifiers
,Section D: Endocrine, Gastrointestinal & Infectious Disease Medications (Page 17)
Questions 141–200
Insulins, Oral Antidiabetics, Thyroid Medications, PPIs, H2 Blockers, Antiemetics,
Antibiotics, Antivirals, Antifungals
Section E: Neurological, Psychotropic & Pain Medications (Page 24)
Questions 201–250
Anticonvulsants, Antiparkinson Agents, Opioid Analgesics, NSAIDs, Benzodiazepines,
SSRIs, Antipsychotics
Section F: Special Populations & Comprehensive Review (Page 30)
Questions 251–300
Pediatric Dosing, Geriatric Considerations, Pregnancy Categories, Herbal Interactions,
NGN Case Scenarios
Complete Answer Key & Explanations (Page 36)
Exam Overview
Purpose: The ATI Capstone Pharmacology Assessment evaluates proficiency in
pharmacological principles, medication safety, and clinical judgment aligned with the
NCLEXRN test plan and Next Generation NCLEX (NGN) standards. The exam measures
knowledge of pharmacokinetic/pharmacodynamic concepts, medication administration
safety, systemspecific drug classes, special population considerations, drug interaction
recognition, adverse effect monitoring, and patient education strategies.
,Format: 300 multiplechoice questions (A, B, C, D). One correct answer per question unless
otherwise specified. Some questions include NGNstyle clinical scenarios.
Duration: Suggested 3.5 hours (approx. 45 seconds per question).
Marking: No negative marking. Each question carries 1 mark.
Cognitive Levels Tested:
Recall (20%): Drug classifications, mechanisms of action, key facts.
Comprehension (30%): Understanding therapeutic effects and rationales.
Application (30%): Applying knowledge to clinical scenarios.
Analysis/Clinical Judgment (20%): Prioritizing, evaluating, and managing complex patient
situations.
Content Areas (Based on ATI Capstone Blueprint):
Medication Administration & Safety (17%)
Pharmacokinetics/Pharmacodynamics (10%)
Cardiovascular & Respiratory Medications (25%)
Endocrine, GI & Infectious Disease Medications (25%)
Neurological, Psychotropic & Pain Medications (15%)
Special Populations & Comprehensive Review (8%)
Section A: Medication Administration & Safety (Q1–50)
, The Rights of Medication Administration, HighAlert Medications, LASA Drugs, Medication
Reconciliation, Error Prevention & Reporting, Dosage Calculations
1. A nurse is preparing to administer a highalert medication. Which action should the nurse
take to ensure the "Right Dose"?
A) Have another nurse perform an independent doublecheck
B) Administer the medication as quickly as possible
C) Verify the dose with the client
D) Check the medication label once before administration
2. A nurse is caring for a client who is receiving a continuous IV infusion of heparin. The
nurse should expect to administer which medication if the client experiences a heparin
overdose?
A) Vitamin K
B) Protamine sulfate
C) Naloxone
D) Acetylcysteine
3. A nurse is providing teaching to a client who has a new prescription for oral
extendedrelease potassium chloride tablets. What instruction should the nurse include?
A) Crush the medication before swallowing
B) Take the medication on an empty stomach
C) Do not crush this medication
D) Dissolve the tablet in orange juice before taking
4. A nurse is caring for a client who has a prescription for vancomycin 1 g IV intermittent
infusion over 30 minutes every 12 hours. What should the nurse do?
A) Administer the medication as prescribed
Comprehensive Test Bank & Exam Preparation Guide
Exam: ATI Capstone Pharmacology Assessment 1 & 2
Format: NGNAligned Multiple Choice & Clinical Judgment Questions
Total Questions: 300
Cognitive Levels: Recall, Comprehension, Application, Analysis, Clinical Judgment
Table of Contents
Exam Overview & Instructions (Page 2)
Section A: Medication Administration & Safety (Page 3)
Questions 1–50
The Rights of Medication Administration, HighAlert Medications, LASA Drugs, Medication
Reconciliation, Error Prevention & Reporting, Dosage Calculations
Section B: Pharmacokinetics & Pharmacodynamics (Page 7)
Questions 51–80
Absorption, Distribution, Metabolism, Excretion, Therapeutic Index, Drug Interactions
Section C: Cardiovascular & Respiratory Medications (Page 10)
Questions 81–140
Antihypertensives, Anticoagulants, Antiplatelets, Digoxin, Diuretics, Bronchodilators,
Corticosteroids, Leukotriene Modifiers
,Section D: Endocrine, Gastrointestinal & Infectious Disease Medications (Page 17)
Questions 141–200
Insulins, Oral Antidiabetics, Thyroid Medications, PPIs, H2 Blockers, Antiemetics,
Antibiotics, Antivirals, Antifungals
Section E: Neurological, Psychotropic & Pain Medications (Page 24)
Questions 201–250
Anticonvulsants, Antiparkinson Agents, Opioid Analgesics, NSAIDs, Benzodiazepines,
SSRIs, Antipsychotics
Section F: Special Populations & Comprehensive Review (Page 30)
Questions 251–300
Pediatric Dosing, Geriatric Considerations, Pregnancy Categories, Herbal Interactions,
NGN Case Scenarios
Complete Answer Key & Explanations (Page 36)
Exam Overview
Purpose: The ATI Capstone Pharmacology Assessment evaluates proficiency in
pharmacological principles, medication safety, and clinical judgment aligned with the
NCLEXRN test plan and Next Generation NCLEX (NGN) standards. The exam measures
knowledge of pharmacokinetic/pharmacodynamic concepts, medication administration
safety, systemspecific drug classes, special population considerations, drug interaction
recognition, adverse effect monitoring, and patient education strategies.
,Format: 300 multiplechoice questions (A, B, C, D). One correct answer per question unless
otherwise specified. Some questions include NGNstyle clinical scenarios.
Duration: Suggested 3.5 hours (approx. 45 seconds per question).
Marking: No negative marking. Each question carries 1 mark.
Cognitive Levels Tested:
Recall (20%): Drug classifications, mechanisms of action, key facts.
Comprehension (30%): Understanding therapeutic effects and rationales.
Application (30%): Applying knowledge to clinical scenarios.
Analysis/Clinical Judgment (20%): Prioritizing, evaluating, and managing complex patient
situations.
Content Areas (Based on ATI Capstone Blueprint):
Medication Administration & Safety (17%)
Pharmacokinetics/Pharmacodynamics (10%)
Cardiovascular & Respiratory Medications (25%)
Endocrine, GI & Infectious Disease Medications (25%)
Neurological, Psychotropic & Pain Medications (15%)
Special Populations & Comprehensive Review (8%)
Section A: Medication Administration & Safety (Q1–50)
, The Rights of Medication Administration, HighAlert Medications, LASA Drugs, Medication
Reconciliation, Error Prevention & Reporting, Dosage Calculations
1. A nurse is preparing to administer a highalert medication. Which action should the nurse
take to ensure the "Right Dose"?
A) Have another nurse perform an independent doublecheck
B) Administer the medication as quickly as possible
C) Verify the dose with the client
D) Check the medication label once before administration
2. A nurse is caring for a client who is receiving a continuous IV infusion of heparin. The
nurse should expect to administer which medication if the client experiences a heparin
overdose?
A) Vitamin K
B) Protamine sulfate
C) Naloxone
D) Acetylcysteine
3. A nurse is providing teaching to a client who has a new prescription for oral
extendedrelease potassium chloride tablets. What instruction should the nurse include?
A) Crush the medication before swallowing
B) Take the medication on an empty stomach
C) Do not crush this medication
D) Dissolve the tablet in orange juice before taking
4. A nurse is caring for a client who has a prescription for vancomycin 1 g IV intermittent
infusion over 30 minutes every 12 hours. What should the nurse do?
A) Administer the medication as prescribed
