ATI PHARMACOLOGY GASTROINTESTINAL SYSTEM TEST EXAM:
100% EXPERT VERIFIED STUDY GUIDE REAL TESTING
2026|2027 QUESTIONS DETAILED ANSWERS AND INSTRUCTOR
NOTE FOR A+ GUARANTEED PASS
A nurse is caring for a client who is taking phenytoin for a seizure disorder and has a new
prescription for sucralfate to treat a duodenal ulcer. The nurse should instruct the client to take
the drugs at least 2 hr apart for which of the following reasons? - Answers -Sucralfate interferes
with the absorption of phenytoin.
A nurse is caring for a client who has a new prescription for ranitidine to treat GERD. The nurse
should instruct the client to wait at least 1 hr between taking ranitidine and which of the
following over-the-counter drugs? - Answers -Antacids
A nurse should recognize that diphenoxylate/atropine should be used with caution for a client
who has which of the following conditions? - Answers -Inflammatory bowel disease
A nurse should recognize that sulfasalazine is contraindicated for clients who have which of the
following conditions? - Answers -Aspirin sensitivity
Which of the following drugs has protocols that require clients to meet specific risk-
management criteria and sign a treatment agreement before the nurse can administer the
drug? - Answers -Alosetron
1|Page
, A nurse should recognize that misoprostol is contraindicated for a client who has which of the
following conditions? - Answers -A positive pregnancy test
A nurse is planning teaching for a client who has been prescribed loperamide to treat diarrhea.
Which of the following statements should the nurse plan to include? - Answers -"Avoid driving
or activities requiring alertness."
A nurse is reviewing the medical record of a client who has a new prescription for ranitidine.
The nurse should recognize that which of the following drugs interacts with ranitidine? -
Answers -Ketoconazole
A nurse is teaching a client who recently had a myocardial infarction and has a new prescription
for docusate sodium. The nurse should inform the client that docusate sodium has which of the
following therapeutic effects? - Answers -Prevents straining
A nurse is caring for a male client who asks the nurse about taking alosetron for irritable bowel
syndrome with diarrhea (IBS-D) lasting 3 months. Which of the following information should the
nurse provide the client about alosetron? - Answers -The drug is prescribed to female clients
who have IBS-D lasting more than 6 months.
A nurse is caring for an older adult client who has renal impairment and a new prescription for
cimetidine. The nurse should instruct the client to report which of the following manifestations?
- Answers -Lethargy
2|Page
100% EXPERT VERIFIED STUDY GUIDE REAL TESTING
2026|2027 QUESTIONS DETAILED ANSWERS AND INSTRUCTOR
NOTE FOR A+ GUARANTEED PASS
A nurse is caring for a client who is taking phenytoin for a seizure disorder and has a new
prescription for sucralfate to treat a duodenal ulcer. The nurse should instruct the client to take
the drugs at least 2 hr apart for which of the following reasons? - Answers -Sucralfate interferes
with the absorption of phenytoin.
A nurse is caring for a client who has a new prescription for ranitidine to treat GERD. The nurse
should instruct the client to wait at least 1 hr between taking ranitidine and which of the
following over-the-counter drugs? - Answers -Antacids
A nurse should recognize that diphenoxylate/atropine should be used with caution for a client
who has which of the following conditions? - Answers -Inflammatory bowel disease
A nurse should recognize that sulfasalazine is contraindicated for clients who have which of the
following conditions? - Answers -Aspirin sensitivity
Which of the following drugs has protocols that require clients to meet specific risk-
management criteria and sign a treatment agreement before the nurse can administer the
drug? - Answers -Alosetron
1|Page
, A nurse should recognize that misoprostol is contraindicated for a client who has which of the
following conditions? - Answers -A positive pregnancy test
A nurse is planning teaching for a client who has been prescribed loperamide to treat diarrhea.
Which of the following statements should the nurse plan to include? - Answers -"Avoid driving
or activities requiring alertness."
A nurse is reviewing the medical record of a client who has a new prescription for ranitidine.
The nurse should recognize that which of the following drugs interacts with ranitidine? -
Answers -Ketoconazole
A nurse is teaching a client who recently had a myocardial infarction and has a new prescription
for docusate sodium. The nurse should inform the client that docusate sodium has which of the
following therapeutic effects? - Answers -Prevents straining
A nurse is caring for a male client who asks the nurse about taking alosetron for irritable bowel
syndrome with diarrhea (IBS-D) lasting 3 months. Which of the following information should the
nurse provide the client about alosetron? - Answers -The drug is prescribed to female clients
who have IBS-D lasting more than 6 months.
A nurse is caring for an older adult client who has renal impairment and a new prescription for
cimetidine. The nurse should instruct the client to report which of the following manifestations?
- Answers -Lethargy
2|Page