alogia poverty of thought/speech
avolition low goal directed behavior
aphasia language issue
apraxia motor issue
agnosia issue naming ppl/objects
dysarthia articulation issue
anomia word finding "naming" issue
ideomotor apraxia issue putting idea into movement
paraparesis lower limb weakness
paraplegia lower body paralyzed
dementia pugilistica boxing dementia progressive
anosognosia poor insight
transient tic 1-12 months
tourettes high dopamine. 1 verbal and several motor. haldol tx.
new neurons aka neurogenesis; in hippocampus and caudate nucleus
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neuron parts dendrite
axon
cell body (soma)
all-or-none principle stimulation in neuron exceeds threshold; the action potential will be the same
intensity
synaptic transmission neurotransmitter released into synaptic cleft
Ach alzeheimer's memory issues (drugs slow breakdown of Ach)
dopamine personality, mood, memory, sleep.
dopamine hypothesis: too much in schizo
motor diseases: tourette's (too much), parkinsons (breakdown)
norepiniphrine mood, attn, dreaming, learning, autonomic
catecholamine hypothesis: low in depression
serotonin (5HT) inhibitory effect: mood, hunger, temp. sex, arousal, sleep, aggression, migraine.
high in schizo, autism, anorexia food restriction
low in bulimia, ptsd, ocd, depression, suicide, social phobia
GABA eating, seizure, anxiety, huntingtons
low in anxiety
glutamate learning, memory, LTP.
too much in excitotoxicity, alzeheimers, hungtingtons
endorphins analgesis pain relief. prevent release of substance P.
"runner's high"
CNS brain and spinal cord (connects to PNS)
PNS somatic nervous
autonomic nervous (parasympathetic - decrease, and sympathetic-fight or flight)
relays info between cns and body organs
cervical damage quadriplegia (arms and legs)
thoracic damage paraplegia (legs)
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hydrocephalus build up of fluid of ventricles in brain
brain development stages (5) 1. proliferation
2. migration
3. differentiation
4. myelination
5. synaptogenesis
please make different motor signs
CT/xray structure only
PET scan/fMRI bloodflow and function
hindbrain medulla (breathing, heart, bp,) pons (connects 2 halves of cerebellum, integrates
movements of both sides, relaxation) cerebellum (balance and posture)
cerebellum damage produces aTAXia ; slurred speech, severe tremors, loss of balance (like
alcohol effects)
midbrain superior and inferior colliculi
substantia nigra
reticular formation (RAS- consciousness, arousal and wakefullness)
forebrain : subcortical thalamus
hypothalamus
basal ganglia
limbic system
hypothalamus hypothalamus- learning/memory, hunger, sleep, sex, thirst, temp, emo
(uncontrollable anger/rage/agg). homeostatis. houses the suprachiasmatic nucleus
(SCN) for circadian rhythm and sleep cycles and SAD
thalamus thalamus- relay, wernicke 1st (ataxia,confusion,eye moviements) then korsakoff-
antero and retrograde amnesia and confabulation (low thiamine)
basal ganglia- motor actions caudate nucleus
putamen
globus pallidus
limbic system- emotion amygdala (fear/aggression, flashbulb) Buci syndrome
hippocampus (learning/memory, stm to ltm)
cingulate cortex (pain)
cerebral cortex 80% of brain weight, 4 lobes
corpus callosum fibers connect 2 hemispheres (epilepsy it is severed)
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dominant- left hemisphere logical/analytical thinking , language, positive emotions
nondominant- right hemisphere creativity, facial recognition, spatial relationship
frontal lobe broca's area (expressive), primary motor cortex, complex
hemiplegia loss of muscle tone
parietal lobe somatosensory cortex
damage= apraxia, anosognosia
gerstmann= agraphia, acalcula, finger agnosia
temporal lobe auditory cortex
wernicke's area (comprehension), antero/retrograde amnesia
right lobe = nonverbal
occipital lobe visual cortex
split-brain patient can name object in right visual field, but can't pick it up with left hand
trichromatic theory red blue green
opponent-process theory 3 bipolar receptors
color blindness x chromosome (more males; most common is red/green) if female to get, both
parents must give her traits
gate-control theory too much info, cells in spinal cord block incoming pain signals (massage, heat/cold,
mental activites)
coping strategies active is better than passive (exercise vs restricting activity)
synesthesia joining senses
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