ATI MED-SURG 1 — GASTROINTESTINAL
ORIGINAL PRACTICE QUESTIONS (SET B)150
NEW QUESTIONS | DIFFERENT ANGLES ·
DIFFERENT SCENARIOS · DIFFERENT
MEDICATIONS
These are original study questions written from standard
medical-surgical nursing curriculum content. They are not
reproduced from any commercial ATI test bank or proctored
exam. This set is completely different from the previous 150.
Topic 1: GI Medications & Nursing Considerations (1–25)
1. A nurse is administering ondansetron to a client receiving
chemotherapy. Which side effect should the nurse monitor
for?
A. Bradycardia
B. Headache and constipation
C. Hypertension
D. Weight gain
Answer: B
Rationale: Ondansetron commonly causes headache,
constipation, and QT prolongation. Monitor ECG in at-risk clients.
,2. A client is prescribed metoclopramide. Which adverse
effect requires immediate intervention?
A. Mild nausea
B. Tardive dyskinesia and extrapyramidal symptoms
C. Constipation
D. Dry mouth
Answer: B
Rationale: Metoclopramide can cause tardive dyskinesia and EPS.
Report involuntary movements immediately.
3. A nurse is teaching a client about docusate sodium. Which
statement indicates understanding?
A. "It is a stimulant laxative."
B. "It is a stool softener that works within 12–72 hours."
C. "It works immediately."
D. "It should be taken with dairy products."
Answer: B
Rationale: Docusate is an emollient (stool softener) that works
within 12–72 hours. It is not a stimulant.
4. A client is prescribed bisacodyl. Which instruction is
correct?
A. "Take with milk."
B. "Swallow the tablet whole; do not crush or chew."
C. "Take on an empty stomach only."
D. "Take at bedtime with food."
,Answer: B
Rationale: Bisacodyl is enteric-coated and should be swallowed
whole to avoid gastric irritation.
5. A nurse is administering loperamide to a client with
diarrhea. Which finding requires holding the medication?
A. Mild abdominal cramping
B. Fever and bloody diarrhea
C. Nausea
D. Frequency of stools
Answer: B
Rationale: Loperamide is contraindicated in infectious diarrhea
with fever or bloody stools because it can worsen infection.
6. A client is prescribed psyllium. Which instruction is most
important?
A. "Take with a full glass of water."
B. "Take on an empty stomach."
C. "Take with milk."
D. "Take at bedtime."
Answer: A
Rationale: Psyllium (bulk-forming laxative) must be taken with a
full glass of water to prevent esophageal obstruction.
7. A nurse is teaching a client about famotidine. Which
statement indicates understanding?
, A. "It neutralizes stomach acid."
B. "It reduces acid production by blocking histamine H2
receptors."
C. "It coats the ulcer."
D. "It kills H. pylori."
Answer: B
Rationale: Famotidine is an H2 receptor antagonist that reduces
gastric acid secretion.
8. A client is prescribed omeprazole. Which instruction is
correct?
A. "Take it 30 minutes before breakfast."
B. "Take it with meals."
C. "Take it at bedtime only."
D. "Take it PRN for pain."
Answer: A
Rationale: PPIs should be taken 30 minutes before the first meal
of the day for maximum effectiveness.
9. A nurse is administering misoprostol to a client taking
NSAIDs. Which finding requires holding the medication?
A. Mild nausea
B. Pregnancy
C. Headache
D. Constipation
Answer: B
ORIGINAL PRACTICE QUESTIONS (SET B)150
NEW QUESTIONS | DIFFERENT ANGLES ·
DIFFERENT SCENARIOS · DIFFERENT
MEDICATIONS
These are original study questions written from standard
medical-surgical nursing curriculum content. They are not
reproduced from any commercial ATI test bank or proctored
exam. This set is completely different from the previous 150.
Topic 1: GI Medications & Nursing Considerations (1–25)
1. A nurse is administering ondansetron to a client receiving
chemotherapy. Which side effect should the nurse monitor
for?
A. Bradycardia
B. Headache and constipation
C. Hypertension
D. Weight gain
Answer: B
Rationale: Ondansetron commonly causes headache,
constipation, and QT prolongation. Monitor ECG in at-risk clients.
,2. A client is prescribed metoclopramide. Which adverse
effect requires immediate intervention?
A. Mild nausea
B. Tardive dyskinesia and extrapyramidal symptoms
C. Constipation
D. Dry mouth
Answer: B
Rationale: Metoclopramide can cause tardive dyskinesia and EPS.
Report involuntary movements immediately.
3. A nurse is teaching a client about docusate sodium. Which
statement indicates understanding?
A. "It is a stimulant laxative."
B. "It is a stool softener that works within 12–72 hours."
C. "It works immediately."
D. "It should be taken with dairy products."
Answer: B
Rationale: Docusate is an emollient (stool softener) that works
within 12–72 hours. It is not a stimulant.
4. A client is prescribed bisacodyl. Which instruction is
correct?
A. "Take with milk."
B. "Swallow the tablet whole; do not crush or chew."
C. "Take on an empty stomach only."
D. "Take at bedtime with food."
,Answer: B
Rationale: Bisacodyl is enteric-coated and should be swallowed
whole to avoid gastric irritation.
5. A nurse is administering loperamide to a client with
diarrhea. Which finding requires holding the medication?
A. Mild abdominal cramping
B. Fever and bloody diarrhea
C. Nausea
D. Frequency of stools
Answer: B
Rationale: Loperamide is contraindicated in infectious diarrhea
with fever or bloody stools because it can worsen infection.
6. A client is prescribed psyllium. Which instruction is most
important?
A. "Take with a full glass of water."
B. "Take on an empty stomach."
C. "Take with milk."
D. "Take at bedtime."
Answer: A
Rationale: Psyllium (bulk-forming laxative) must be taken with a
full glass of water to prevent esophageal obstruction.
7. A nurse is teaching a client about famotidine. Which
statement indicates understanding?
, A. "It neutralizes stomach acid."
B. "It reduces acid production by blocking histamine H2
receptors."
C. "It coats the ulcer."
D. "It kills H. pylori."
Answer: B
Rationale: Famotidine is an H2 receptor antagonist that reduces
gastric acid secretion.
8. A client is prescribed omeprazole. Which instruction is
correct?
A. "Take it 30 minutes before breakfast."
B. "Take it with meals."
C. "Take it at bedtime only."
D. "Take it PRN for pain."
Answer: A
Rationale: PPIs should be taken 30 minutes before the first meal
of the day for maximum effectiveness.
9. A nurse is administering misoprostol to a client taking
NSAIDs. Which finding requires holding the medication?
A. Mild nausea
B. Pregnancy
C. Headache
D. Constipation
Answer: B
