COMSAE COMPREHENSIVE STUDY GUIDE:
EXAM PREPARATION AND PRACTICE
REVIEW GRADED A+
Pseudohypoparathydoidism
Albrights hereditary osteodystrophy autosomal dominant kidney unresponsiveness to PTH.
leads to hypocalcemia, shortened 4th/5th digits, short stature.
Trousseau's Syndrome
a migratory thrombophlebitis - presents with redness and tenderness on palpation of
extremities. associated with a visceral malignancy mostly pancreatic adenocarcinoma or
adenocarcinoma of the colon and lung etc.
treatment for legionares?
respiratory floroquinolone
Polyostotic fibrous dysplasia
bone is replaced by fibroblasts, collagen and irregular bony trabeculae.
McCune-Albright Syndrome
a form of polyostotic fibrous dysplasia characterized by multiple unilateral bone lesions
associated with endocrine abnormalities (precocious puberty) and cafe au lait spots.
,treatment for tinea versicolor
selenium sulfatide, topical miconazole
Papillary thyroid carcinoma
malignant - good prognosis, lymphatic spread, most common thyroid cancer, papillary growth
with optically clear nuclie (orphan annie nuclie) (ground glass chromatin)
Clomiphine
a SERM that inhibits negative feedback of estrogen in the hypothalamus on gonadotropin
release causing an increased release of LH and FSH from the anterior pituitary glans which
stimulates ovulation. It is used to treat infertility in the setting of PCOS.
Osteitis fibrosa cystica
bone pain, subperiosteal bone resorption on the radial aspect of middle phalanges along with
brown tumors of the long bones.
Carcinoid Syndrome
flushing wheezing, diahrrea and right sided valvular lesions especially tricuspid regurgitation.
needs to have metastasized to the liver because if not and its in the GI tract it is subject to first
pass effect so you will not see symptoms.
causes of epiddymitis >35 yo
,ecoli, pseudomonas, proteus
causes of epididymitis < 35 yo
chlamydia, gonnohrea.
Fanconi's syndrome
proximal tubular reabsorption defect
polyuria, renal tubular acidosis type II, growth failure, electrolyte imbalances,
hypophosphatemic rickets.
GP120
HIV docking protein in viral envelope, formed from cleavage of GP160. responsible for
attachment to host CD4+ T cell.
ENV
GP41
HIV transmembrane protein in viral envelope, formed from cleavage of gp160. responsible for
fusion and entry.
ENV
p24
gag - HIV capsid protein
, pol codes for?
reverse transcriptase, aspartate protease, integrase.
B1
thiamine: TPP
B2
riboflavin: FAD, FMN
B3
Niacin: NAD+
B5
pantothenic acid: CoA
B6
pyridoxine: PLP
EXAM PREPARATION AND PRACTICE
REVIEW GRADED A+
Pseudohypoparathydoidism
Albrights hereditary osteodystrophy autosomal dominant kidney unresponsiveness to PTH.
leads to hypocalcemia, shortened 4th/5th digits, short stature.
Trousseau's Syndrome
a migratory thrombophlebitis - presents with redness and tenderness on palpation of
extremities. associated with a visceral malignancy mostly pancreatic adenocarcinoma or
adenocarcinoma of the colon and lung etc.
treatment for legionares?
respiratory floroquinolone
Polyostotic fibrous dysplasia
bone is replaced by fibroblasts, collagen and irregular bony trabeculae.
McCune-Albright Syndrome
a form of polyostotic fibrous dysplasia characterized by multiple unilateral bone lesions
associated with endocrine abnormalities (precocious puberty) and cafe au lait spots.
,treatment for tinea versicolor
selenium sulfatide, topical miconazole
Papillary thyroid carcinoma
malignant - good prognosis, lymphatic spread, most common thyroid cancer, papillary growth
with optically clear nuclie (orphan annie nuclie) (ground glass chromatin)
Clomiphine
a SERM that inhibits negative feedback of estrogen in the hypothalamus on gonadotropin
release causing an increased release of LH and FSH from the anterior pituitary glans which
stimulates ovulation. It is used to treat infertility in the setting of PCOS.
Osteitis fibrosa cystica
bone pain, subperiosteal bone resorption on the radial aspect of middle phalanges along with
brown tumors of the long bones.
Carcinoid Syndrome
flushing wheezing, diahrrea and right sided valvular lesions especially tricuspid regurgitation.
needs to have metastasized to the liver because if not and its in the GI tract it is subject to first
pass effect so you will not see symptoms.
causes of epiddymitis >35 yo
,ecoli, pseudomonas, proteus
causes of epididymitis < 35 yo
chlamydia, gonnohrea.
Fanconi's syndrome
proximal tubular reabsorption defect
polyuria, renal tubular acidosis type II, growth failure, electrolyte imbalances,
hypophosphatemic rickets.
GP120
HIV docking protein in viral envelope, formed from cleavage of GP160. responsible for
attachment to host CD4+ T cell.
ENV
GP41
HIV transmembrane protein in viral envelope, formed from cleavage of gp160. responsible for
fusion and entry.
ENV
p24
gag - HIV capsid protein
, pol codes for?
reverse transcriptase, aspartate protease, integrase.
B1
thiamine: TPP
B2
riboflavin: FAD, FMN
B3
Niacin: NAD+
B5
pantothenic acid: CoA
B6
pyridoxine: PLP
