Intro To Abo Blood Group System Expected Questions With Verified Answers

INTRO TO ABO BLOOD GROUP SYSTEM EXPECTED
QUESTIONS WITH VERIFIED ANSWERS

Question 1.
Why does agglutination (clumping) sometimes occur when red blood cells (RBCs) from one
individual are mixed with serum from another?

ANSWER
Antibodies in one person's serum may react with antigens on the other person's RBCs.


Question 2.
Contains Anti-B antibodies in serum

ANSWER
blood group A


Question 3.
Has A and B antigens on the RBCs.

ANSWER
Blood group AB


Question 4.
Has neither A nor B antigens.

ANSWER
Blood group O


Question 5.
In order to determine the ABO type, known antisera are mixed with patient RBCs and known red
cells are mixed with patient serum.

ANSWER
True




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, Question 6.
Which is the predominant immunoglobulin class for anti-A and anti-B antibodies?

ANSWER
IgM


Question 7.
Why Knowledge of A Subgroups Is Important For Lab oratory Professionals

ANSWER
- The antigen may be so weak that it is not detected and the red cells are mistyped as group O.
This is especially dangerous if the cells are those of a donor.


Question 8.
Which of the following is the most common subgroup of A?

ANSWER
A1


Question 9.
Degrees of agglutination

ANSWER
4+ agglutination: Red blood cell button is a solid agglutinate; clear background.


Question 10.
Forward typing

ANSWER
Done using known antisera to detect ABO antigens present on patient red cells


Question 11.
Reverse Typing

ANSWER
Testing of patient serum for the presence of ABO antibodies. Patient serum mixed with known
red cells.




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