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Exam (elaborations)

NR 565 Advanced Pharmacology Final Exam Study Guide 2026|High Quality Q&A

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NR 565 Advanced Pharmacology Final Exam Study Guide 2026|High Quality Q&A

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NR 565 Advanced Pharmacology Final
Exam Study Guide 2026|High Quality
Q&A


Bronchodilators - correct-answer-Relax smooth muscle in lungs, prevent bronchi

spasms, make it easier for air to move. Include the following drug classes: long

acting beta 2 agonists, short acting beta 2 agonists, xanthine derivatives, and

anticholinergics (muscarinic agonists or LAMAs)




Anti-inflammatory agents for respiratory disease - correct-answer-Decrease

inflammatory mechanisms in the airway. Include medications such as inhaled and

systemic glucocorticoids, leukotriene receptor antagonists, mast cell stabilizers,

and phosphodiesterase-4 inhibitors.




Inhalation Devices - correct-answer-Metered-dose inhalers (MDIs)- pressurized

device that delivers a measured dose of the drug with each actuation; activated

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by breath so must have hand/breath coordination. Begin inhaling before

activation the device. Spacer can help with drug delivery and hand/breath

coordination

Dry-powder inhalers (DPIs)- need quick, deep breath. Difficult to use for patients

with advanced disease.

Nebulizers- take a long time.

Soft mist inhalers - longer, slower delivery of a fine mist. Activated by user .




Ipatropium - correct-answer-anticholinergic muscarinic antagonist used to treat

COPD. Bronchodilator. Can be used off label for asthma. Can be combined with a

beta 2 agonists because the two medications promote bronchodilation via

different mechanisms.




Ipatropium adverse effects - correct-answer-paradoxic acute bronchospam,

cough hoarseness, throat irritation

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Monoclonal antibodies - correct-answer-Manage airway inflammation;

specifically, antagonist of IgE or interleukin receptors.




Monoclonal antibodies indications - correct-answer-For allergic asthma not

responsive to glucocorticoids.




How are monoclonal antibodies administered? - correct-answer-SubQ




Example of a monoclonal antibody for asthma - correct-answer-Omalizumab




Monoclonal antibodies black box warning - correct-answer-Anaphylaxis may

occur at any time during treatment. Carry an epi pen.

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Bronchodilators MOA - correct-answer-Symptomatic relief for asthma and copd .

First line treatment for asthma.




Most effective bronchodilator - correct-answer-Beta2 agonists




Beta 2 agonists - correct-answer-albuterol, salmeterol




short acting beta 2 agonists - correct-answer-albuterol, levalbuterol

As needed for attacks. Can be used prior to exercise to prevent an attack.




long acting beta 2 agonists - correct-answer-Salmeterol

Formoterol

For patients with frequent asthma attacks (combined with a glucocorticoids). Can

be used alone for stable COPD

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