TEST BANK
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Introduction to Genetic Analysis
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Anthony J.F. Griffiths, John Doebley, Catherine Peichel, and David A. Wassarman
/# /# /# /# /# /# /# /# /# /#
12th Edition
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PlusBay.Plus
,Table of Contents
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Chapter 01 The Genetics Revolution
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Chapter 02 Single Gene Inheritance
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Chapter 03 Independent Assortment of Genes
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Chapter 04 Mapping Eukaryote Chromosomes by Recombination
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Chapter 05 Gene Interaction
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Chapter 06 The Genetics of Bacteria and Their Viruses
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Chapter 07 DNA Structure and Replication
/# /# /# /# /# 104
Chapter 08 RNA Transcription Processing and Decay
/# /# /# /# /# /# 117
Chapter 09 Proteins and Their Synthesis
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Chapter 10 Gene Isolation and Manipulation
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Chapter 11 Regulation of Gene Expression in Bacteria and Their Viruses
/# /# /# /# /# /# /# /# /# /# 160
Chapter 12 Regulation of Gene Expression in Eukaryotes
/# /# /# /# /# /# /# 175
Chapter 13 The Genetic Control of Development
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Chapter 14 Genomes and Genomics
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Chapter 15 DNA Damage Repair and Recombination
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Chapter 16 The Dynamic Genome Transposable Elements
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Chapter 17 Large Scale Chromosomal Changes
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Chapter 18 Population Genetics
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Chapter 19 The Inheritance of Complex Traits
/# /# /# /# /# /# 258
Chapter 20 Evolution of Genes and Traits
/# /# /# /# /# /# 270
PlusBay.Plus
, Test/#Bank/#-/#Introduction/#to/#Genetic/#Analysis,/#12th/#Edition/#(Griffiths,/#2021)
Chapter 01: The Genetics Revolution
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1. The early 1900s was an important period for genetics due to which of the following major events?
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a. the rediscovery of Gregor Mendel's scientific findings
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b. Watson and Crick solving the structure of DNA /# /# /# /# /# /# /#
c. Walter Sutton and Theodore Boveri hypothesizing that chromosomes are the hereditary elements
/# /# /# /# /# /# /# /# /# /# /#
d. the rediscovery of Gregor Mendel's scientific findings and Walter Sutton and Theodore Boveri
/# /# /# /# /# /# /# /# /# /# /# /# /#
hypothesizing that chromosomes are the hereditary elements /# /# /# /# /# /#
e. All of the answer options are correct.
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ANSWER: e / #
2. A sample of normal double-
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stranded DNA was found to have a guanine content of 18%. What is the expected proportion of adenine?
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a. 9%
b. 32%
c. 36%
d. 68%
e. 82%
ANSWER: b / #
3. In one strand of DNA, the nucleotide sequence is 5'-ATGC-
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3'. The complementary sequence in the other strand must be
/# /# /# /# /# /# /# /# /#
a. 3'-ATGC-5'.
b. 3'-TACG-5'.
c. 5'-ATCG-3'.
d. 5'-CGTA-3'.
e. 5'-TACG-3'.
ANSWER: b / #
4. How many different DNA molecules that are eight-nucleotide-pairs long are theoretically possible?
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a. 24
b. 32
c. 64
d. 256
e. 65,536
ANSWER: e / #
5. Which of the following is/are TRUE about genes?
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a. Genes are located on chromosomes. /# /# /# /#
b. Genes come in variants known as alleles. /# /# /# /# /# /#
c. Genes usually encode protein products. /# /# /# /#
d. All of the answer options are correct.
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e. None of the answer options is correct./# /# /# /# /# /#
ANSWER: d / #
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PlusBay.Plus
, Test/#Bank/#-/#Introduction/#to/#Genetic/#Analysis,/#12th/#Edition/#(Griffiths,/#2021)
6. Wild cats (Felis silvestris) and common mice (Mus musculus) are diploid. In wild cats, 2n = 38, while in
/# /# /# /# /# /# /# /# /# /# /# /# /# /# /# /# /# /# /#
common mice, 2n = 40. Based on this information, we can conclude that wild-cat cells have
/# /# /# /# /# /# /# /# /# /# /# /# /# /# /#
a. less DNA than common-mouse cells.
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b. smaller genomes than common-mouse cells. /# /# /# /#
c. fewer DNA molecules than common-mouse cells.
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d. fewer genes than common-mouse cells.
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e. fewer sets of chromosomes than common-mouse cells.
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ANSWER: c / #
7. Which of the following is a component of DNA?
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a. alanine
b. arginine
c. cysteine
d. guanine
e. tyrosine
ANSWER: d / #
8. Which of the following is/are TRUE of the DNA structure solved by Watson and Crick?
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a. It is a double-helical structure.
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b. Sugar–phosphate backbone is always toward the outside of the DNA. /# /# /# /# /# /# /# /# /#
c. There are two hydrogen bonds between A and T and three hydrogen bonds between C and G.
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d. There are four types of nitrogenous bases.
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e. All of the answer options are correct.
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ANSWER: e / #
9. Which of the following is a CORRECT representation of the central dogma?
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a. RNA → DNA → protein /# /# /# /#
b. protein → DNA → RNA /# /# /# /#
c. DNA → RNA → protein /# /# /# /#
d. DNA → protein → DNA /# /# /# /#
e. None of the answer options is correct.
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ANSWER: c / #
10. You have come across a dog (named Cindy) that does not have a tail. Interestingly, all the puppies produced
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by this dog don't have a tail. If the lack of tail is caused by a genetic mutation, where has this mutation most lik
/# /# /# /# /# /# /# /# /# /# /# /# /# /# /# /# /# /# /# /# /# /# /#
ely taken place?
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a. in Cindy's gametes
/# /#
b. in the cells that should normally have given rise to Cindy's tail
/# /# /# /# /# /# /# /# /# /# /#
c. in the cells that should normally have given rise to Cindy's and her puppies' tails
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d. in all of Cindy's cells (including her gametes)
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e. in a gamete of one of Cindy's parents
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ANSWER: a / #
11. Which of the following features makes a species suitable as a model organism?
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2|Page/# /# /# /#
PlusBay.Plus
/#
Introduction to Genetic Analysis
/# /# /#
Anthony J.F. Griffiths, John Doebley, Catherine Peichel, and David A. Wassarman
/# /# /# /# /# /# /# /# /# /#
12th Edition
/#
PlusBay.Plus
,Table of Contents
/# /#
Chapter 01 The Genetics Revolution
/# /# /# /# 1
Chapter 02 Single Gene Inheritance
/# /# /# /# 6
Chapter 03 Independent Assortment of Genes
/# /# /# /# /# 26
Chapter 04 Mapping Eukaryote Chromosomes by Recombination
/# /# /# /# /# /# 43
Chapter 05 Gene Interaction
/# /# /# 63
Chapter 06 The Genetics of Bacteria and Their Viruses
/# /# /# /# /# /# /# /# 84
Chapter 07 DNA Structure and Replication
/# /# /# /# /# 104
Chapter 08 RNA Transcription Processing and Decay
/# /# /# /# /# /# 117
Chapter 09 Proteins and Their Synthesis
/# /# /# /# /# 130
Chapter 10 Gene Isolation and Manipulation
/# /# /# /# /# 141
Chapter 11 Regulation of Gene Expression in Bacteria and Their Viruses
/# /# /# /# /# /# /# /# /# /# 160
Chapter 12 Regulation of Gene Expression in Eukaryotes
/# /# /# /# /# /# /# 175
Chapter 13 The Genetic Control of Development
/# /# /# /# /# /# 184
Chapter 14 Genomes and Genomics
/# /# /# /# 192
Chapter 15 DNA Damage Repair and Recombination
/# /# /# /# /# /# 197
Chapter 16 The Dynamic Genome Transposable Elements
/# /# /# /# /# /# 216
Chapter 17 Large Scale Chromosomal Changes
/# /# /# /# /# 225
Chapter 18 Population Genetics
/# /# /# 243
Chapter 19 The Inheritance of Complex Traits
/# /# /# /# /# /# 258
Chapter 20 Evolution of Genes and Traits
/# /# /# /# /# /# 270
PlusBay.Plus
, Test/#Bank/#-/#Introduction/#to/#Genetic/#Analysis,/#12th/#Edition/#(Griffiths,/#2021)
Chapter 01: The Genetics Revolution
/# /# /# /#
1. The early 1900s was an important period for genetics due to which of the following major events?
/# /# /# /# /# /# /# /# /# /# /# /# /# /# /# /#
a. the rediscovery of Gregor Mendel's scientific findings
/# /# /# /# /# /#
b. Watson and Crick solving the structure of DNA /# /# /# /# /# /# /#
c. Walter Sutton and Theodore Boveri hypothesizing that chromosomes are the hereditary elements
/# /# /# /# /# /# /# /# /# /# /#
d. the rediscovery of Gregor Mendel's scientific findings and Walter Sutton and Theodore Boveri
/# /# /# /# /# /# /# /# /# /# /# /# /#
hypothesizing that chromosomes are the hereditary elements /# /# /# /# /# /#
e. All of the answer options are correct.
/# /# /# /# /# /#
ANSWER: e / #
2. A sample of normal double-
/# /# /# /#
stranded DNA was found to have a guanine content of 18%. What is the expected proportion of adenine?
/# /# /# /# /# /# /# /# /# /# /# /# /# /# /# /# /#
a. 9%
b. 32%
c. 36%
d. 68%
e. 82%
ANSWER: b / #
3. In one strand of DNA, the nucleotide sequence is 5'-ATGC-
/# /# /# /# /# /# /# /# /#
3'. The complementary sequence in the other strand must be
/# /# /# /# /# /# /# /# /#
a. 3'-ATGC-5'.
b. 3'-TACG-5'.
c. 5'-ATCG-3'.
d. 5'-CGTA-3'.
e. 5'-TACG-3'.
ANSWER: b / #
4. How many different DNA molecules that are eight-nucleotide-pairs long are theoretically possible?
/# /# /# /# /# /# /# /# /# /# /#
a. 24
b. 32
c. 64
d. 256
e. 65,536
ANSWER: e / #
5. Which of the following is/are TRUE about genes?
/# /# /# /# /# /# /#
a. Genes are located on chromosomes. /# /# /# /#
b. Genes come in variants known as alleles. /# /# /# /# /# /#
c. Genes usually encode protein products. /# /# /# /#
d. All of the answer options are correct.
/# /# /# /# /# /#
e. None of the answer options is correct./# /# /# /# /# /#
ANSWER: d / #
1|Page
/# /# /# /#
PlusBay.Plus
, Test/#Bank/#-/#Introduction/#to/#Genetic/#Analysis,/#12th/#Edition/#(Griffiths,/#2021)
6. Wild cats (Felis silvestris) and common mice (Mus musculus) are diploid. In wild cats, 2n = 38, while in
/# /# /# /# /# /# /# /# /# /# /# /# /# /# /# /# /# /# /#
common mice, 2n = 40. Based on this information, we can conclude that wild-cat cells have
/# /# /# /# /# /# /# /# /# /# /# /# /# /# /#
a. less DNA than common-mouse cells.
/# /# /# /#
b. smaller genomes than common-mouse cells. /# /# /# /#
c. fewer DNA molecules than common-mouse cells.
/# /# /# /# /#
d. fewer genes than common-mouse cells.
/# /# /# /#
e. fewer sets of chromosomes than common-mouse cells.
/# /# /# /# /# /#
ANSWER: c / #
7. Which of the following is a component of DNA?
/# /# /# /# /# /# /# /#
a. alanine
b. arginine
c. cysteine
d. guanine
e. tyrosine
ANSWER: d / #
8. Which of the following is/are TRUE of the DNA structure solved by Watson and Crick?
/# /# /# /# /# /# /# /# /# /# /# /# /# /#
a. It is a double-helical structure.
/# /# /# /#
b. Sugar–phosphate backbone is always toward the outside of the DNA. /# /# /# /# /# /# /# /# /#
c. There are two hydrogen bonds between A and T and three hydrogen bonds between C and G.
/# /# /# /# /# /# /# /# /# /# /# /# /# /# /# /#
d. There are four types of nitrogenous bases.
/# /# /# /# /# /#
e. All of the answer options are correct.
/# /# /# /# /# /#
ANSWER: e / #
9. Which of the following is a CORRECT representation of the central dogma?
/# /# /# /# /# /# /# /# /# /# /#
a. RNA → DNA → protein /# /# /# /#
b. protein → DNA → RNA /# /# /# /#
c. DNA → RNA → protein /# /# /# /#
d. DNA → protein → DNA /# /# /# /#
e. None of the answer options is correct.
/# /# /# /# /# /#
ANSWER: c / #
10. You have come across a dog (named Cindy) that does not have a tail. Interestingly, all the puppies produced
/# /# /# /# /# /# /# /# /# /# /# /# /# /# /# /# /# /# /#
by this dog don't have a tail. If the lack of tail is caused by a genetic mutation, where has this mutation most lik
/# /# /# /# /# /# /# /# /# /# /# /# /# /# /# /# /# /# /# /# /# /# /#
ely taken place?
/# /#
a. in Cindy's gametes
/# /#
b. in the cells that should normally have given rise to Cindy's tail
/# /# /# /# /# /# /# /# /# /# /#
c. in the cells that should normally have given rise to Cindy's and her puppies' tails
/# /# /# /# /# /# /# /# /# /# /# /# /# /#
d. in all of Cindy's cells (including her gametes)
/# /# /# /# /# /# /#
e. in a gamete of one of Cindy's parents
/# /# /# /# /# /# /#
ANSWER: a / #
11. Which of the following features makes a species suitable as a model organism?
/# /# /# /# /# /# /# /# /# /# /# /#
2|Page/# /# /# /#
PlusBay.Plus
