Women's Health Nurse Practitioner (WHNP) Exam 2026:
Comprehensive Graduate & Professional Certification Practice
Examination — Primary Care, Reproductive Health, Prenatal &
Postpartum Care, Gynecologic Conditions, Contraception, Sexual
Health, Women's Oncology, Menopause, Preventive Care & Health
Promotion — 190 Multiple-Choice Questions with Answers &
Detailed Rationales
Section 1: Health Promotion and Disease Prevention (Questions 1-25)
Question 1
A 45-year-old woman presents for her annual well-woman visit. She has no significant
medical history and reports feeling well. According to the American Cancer Society
guidelines, when should she begin routine colorectal cancer screening?
A. Age 40
B. Age 45
C. Age 50
D. Age 55
Correct Answer: B
Explanation: The ACS recommends colorectal cancer screening begin at age 45 for average-
risk individuals, reflecting rising incidence in younger adults.
Question 2
,A 32-year-old woman asks about her risk for breast cancer. Her mother was diagnosed with
breast cancer at age 52. Which risk assessment tool would be most appropriate to calculate
her lifetime risk?
A. Gail Model
B. Tyrer-Cuzick Model
C. BRCA1/2 Mutation Calculator
D. Manchester Scoring System
Correct Answer: A
Explanation: The Gail Model calculates 5-year and lifetime breast cancer risk using family
history and reproductive factors for average-risk women.
Question 3
A 28-year-old woman presents for preconception counseling. She has type 1 diabetes with
an HbA1c of 9.2%. What is the most critical counseling point regarding pregnancy?
A. She should avoid pregnancy entirely
B. Glycemic control should be optimized before conception
C. Insulin requirements will decrease in pregnancy
D. Oral hypoglycemic agents are preferred during pregnancy
Correct Answer: B
Explanation: Preconception glycemic optimization reduces congenital malformations and
miscarriage risk; target HbA1c <6.5% before conception is ideal.
,Question 4
A 55-year-old postmenopausal woman asks about osteoporosis screening. She has no risk
factors and weighs 145 pounds. When should she have her first DEXA scan?
A. Age 50
B. Age 55
C. Age 65
D. Age 70
Correct Answer: C
Explanation: USPSTF recommends osteoporosis screening with DEXA for all women aged 65
and older without risk factors.
Question 5
A 24-year-old woman presents for her first Pap smear. According to current guidelines,
screening should begin at age:
A. 18
B. 21
C. 25
D. 30
Correct Answer: B
Explanation: Cervical cancer screening begins at age 21 regardless of sexual activity, per
ACOG and USPSTF guidelines.
, Question 6
A 38-year-old woman with a history of abnormal Pap smears asks about HPV vaccination.
She is currently 38 and has not been vaccinated. What is the appropriate recommendation?
A. She is too old for the vaccine
B. She should receive the vaccine if age 45 or younger
C. She should only receive the vaccine if she has HPV
D. She should receive only one dose
Correct Answer: B
Explanation: HPV vaccination is approved through age 45; shared decision-making is
recommended for ages 27-45 based on risk factors.
Question 7
A 50-year-old woman presents for her annual exam. She has a BMI of 32 and a family history
of type 2 diabetes. According to ADA guidelines, she should be screened for diabetes:
A. Only if symptomatic
B. Every 5 years
C. Every 3 years
D. Annually
Correct Answer: C
Comprehensive Graduate & Professional Certification Practice
Examination — Primary Care, Reproductive Health, Prenatal &
Postpartum Care, Gynecologic Conditions, Contraception, Sexual
Health, Women's Oncology, Menopause, Preventive Care & Health
Promotion — 190 Multiple-Choice Questions with Answers &
Detailed Rationales
Section 1: Health Promotion and Disease Prevention (Questions 1-25)
Question 1
A 45-year-old woman presents for her annual well-woman visit. She has no significant
medical history and reports feeling well. According to the American Cancer Society
guidelines, when should she begin routine colorectal cancer screening?
A. Age 40
B. Age 45
C. Age 50
D. Age 55
Correct Answer: B
Explanation: The ACS recommends colorectal cancer screening begin at age 45 for average-
risk individuals, reflecting rising incidence in younger adults.
Question 2
,A 32-year-old woman asks about her risk for breast cancer. Her mother was diagnosed with
breast cancer at age 52. Which risk assessment tool would be most appropriate to calculate
her lifetime risk?
A. Gail Model
B. Tyrer-Cuzick Model
C. BRCA1/2 Mutation Calculator
D. Manchester Scoring System
Correct Answer: A
Explanation: The Gail Model calculates 5-year and lifetime breast cancer risk using family
history and reproductive factors for average-risk women.
Question 3
A 28-year-old woman presents for preconception counseling. She has type 1 diabetes with
an HbA1c of 9.2%. What is the most critical counseling point regarding pregnancy?
A. She should avoid pregnancy entirely
B. Glycemic control should be optimized before conception
C. Insulin requirements will decrease in pregnancy
D. Oral hypoglycemic agents are preferred during pregnancy
Correct Answer: B
Explanation: Preconception glycemic optimization reduces congenital malformations and
miscarriage risk; target HbA1c <6.5% before conception is ideal.
,Question 4
A 55-year-old postmenopausal woman asks about osteoporosis screening. She has no risk
factors and weighs 145 pounds. When should she have her first DEXA scan?
A. Age 50
B. Age 55
C. Age 65
D. Age 70
Correct Answer: C
Explanation: USPSTF recommends osteoporosis screening with DEXA for all women aged 65
and older without risk factors.
Question 5
A 24-year-old woman presents for her first Pap smear. According to current guidelines,
screening should begin at age:
A. 18
B. 21
C. 25
D. 30
Correct Answer: B
Explanation: Cervical cancer screening begins at age 21 regardless of sexual activity, per
ACOG and USPSTF guidelines.
, Question 6
A 38-year-old woman with a history of abnormal Pap smears asks about HPV vaccination.
She is currently 38 and has not been vaccinated. What is the appropriate recommendation?
A. She is too old for the vaccine
B. She should receive the vaccine if age 45 or younger
C. She should only receive the vaccine if she has HPV
D. She should receive only one dose
Correct Answer: B
Explanation: HPV vaccination is approved through age 45; shared decision-making is
recommended for ages 27-45 based on risk factors.
Question 7
A 50-year-old woman presents for her annual exam. She has a BMI of 32 and a family history
of type 2 diabetes. According to ADA guidelines, she should be screened for diabetes:
A. Only if symptomatic
B. Every 5 years
C. Every 3 years
D. Annually
Correct Answer: C
