QUESTIONS AND ANSWERS | NURSING
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,Sclerosis Hardening or thickening of a body part
Sclerodactyly Hardening or thickening of the skin, particularly the hands (can cause fingers to turn
inward, like a grip)
Ankylosing Fusion of vertebrae bodies, particularly in the posterior back, that changes the shape of
the bones to become more squarelike
Arthropathy Disease of the joints (i.e., arthritis)
Arthritis Inflammation of the joints
Polyarticular Involving 5 or more joints (i.e., polyarthritis= pain in 5+ joints of the body)
Symmetric Both sides match
Asymmetric Both sides do not match- Disease process effects one side more than the other, or only
affects one side
Rheumatoid/ism/tic Various conditions characterized by inflammation, pain (particularly in joints or fibrous
tissue), and stiffness
Autoimmune Our own antibodies are attacking our body's cells, because they no longer recognize
them as self
Rheumatoid (Rheumatic) Arthritis Genetic + environmental exposure
Autoimmune
Antigens attack collagen
Phagocytic enzymes destroy joint cartilage
Rheumatoid Arthritis Vulnerable Populations More common in women (possibly some connection with estrogen) and aging
Rheumatoid Arthritis Joint Manifestations Symmetric and polyarticular symptoms in freely moving joints
Rheumatoid nodules
Reduced range of motion
Pain and stiffness in morning after waking
Swelling and thickening of synovial space causes ulnar deviation and swan neck
, Rheumatoid Arthritis Diagnosis Rheumatoid factor (self-produced antibody)
Increased erythrocyte sedimentation rate
Rheumatoid Arthritis Treatment Bee-venom
Systemic Lupus Erythematosus (SLE) Genetic + environmental exposure
Autoimmune
Early onset (15-44)
Autoantibodies and immune complexes form with B-cell hyperactivity that produce
autoantibodies (ANA)
Nuclear of antibodies is attacked
SLE Triggers Hormones, environment, UV light
SLE Vulnerable Populations Females
African Americans, Hispanics, Asians
SLE Manifestations Butterfly rash on face
Sun sensitivity
Glomerulonephritis
"The Great Immitator"
SLE Diagnosis Increased ANA, but is is not as simple as a lab test - must meet 4/11 criteria
Anti-DNA test
SLE Treatment Prevent progressive loss of organ function
Systemic Sclerosis/Sclerodema Autoimmune disease of connective tissue
Excessive collagen deposition in skin and internal organs
Fibrosis thickens skin
Systemic Sclerosis Vulnerable Populations Females