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Exam (elaborations)

NURS 340 Exam 1 Medications – Questions & Accurate Answers

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NURS 340 Exam 1 Medications – Questions & Accurate Answers

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NURS 340 Exam 1 Medications – Questions &
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isoniazid indications for use active and latent TB


isoniazid mechanism of action -interferes with lipid and RNA in bacilli
-can be bacteriostatic, @higher doses is bactericidal


isoniazid ADRs -liver damage (hepatitis & failure)
-peripheral Neuropathy (B6 issues)
-N/V
-CNS issues
-DRESS


isoniazid interventions/nursing -Liver enzymes throughout course
actions -monitor GI disturbances
-administer B6 as prescribed
-often given with rifampin

,isoniazid client instructions -adhere to med regimen (6-9 mo)
-monitor for s/sx liver tox
-monitor s/sx neuropathy
-monitor for s/sx of DRESS
-dont take with antacids


rifampin indications for use -tuberculosis, meningitis, leprosy, broad-spectrum
(gram pos and gram neg bacteria)
-prevention of resistance with other TB medication
regimens


rifampin mechanism of action -interferes with RNA
-bacteriostatic and bactericidal to sensitive bacteria


rifampin ADRs -liver tox
-red/orange body fluids
-GI manifestations
-flushin, rash/itching


rifampin interventions/nursing actions -monitor LFTs
-monitor s/sx of liver tox
-monitor for DRESS
-monitor for s/sx of GI distress


rifampin client instructions -take 1 hr before/2 hr after meals
-take with food if GI distress
-adherence to med regimen (resistance risk)
-report GI issues
-birth control


metronidazole indications for use parasitic infections amebiasis, giardiasis,
trichomoniasis


metronidazole mechanism of actions damages DNA so they can't reproduce


metronidazole ADRs -N/V/D and anorexia
-CNS (HA, vertigo, ataxia)
-dark urine

,metronidazole interventions/nursing -encourage food or milk w/meds
actions -monitor CNS effect
-stop the med if seizures occur


metronidazole client instructions -dark urine may occur (expected)
-take 1hr before or 2hr after
-take with food if GI distress


amphotericin B, nystatin indications local and systemic fungal infections
for use


amphotericin B, nystatin mechanism -damage the cell wall of various fungi
of action -fungistatic and fungicidal


amphotericin B, nystatin ADRs -fever, chills, aches, tachycardia
-hypertention (might need bolus)
-HA, nausea
-bone marrow suppression (anemia)
-thrombophlebitis
-renal toxicity/hypo K+


amphotericin B, nystatin -anticipate diphenhydramine
interventions/nursing actions -anticipate acetaminophen
-anticipate renal labs & CBC
-weight
-IV site


amphotericin B, nystatin client -comply with labs
instructions -report s/sx of reaction
-monitor weight
-Nystatin - must swish & swallow
-kidney damage


acyclovir, valacyclovir/Valtrex viral/herpetic infections - HSV, VZ, CMV
indications for use


acyclovir, valacyclovir/Valtrex -interferes with DNA replication
mechanism of action -virustatic* not virucidal

, acyclovir, valacyclovir/Valtrex ADRs -oral: N/V/D, CNS effects, vertigo
-IV: renal tox, CNS tox (rare), tissue damage
-topical: burning, itching, redness


acyclovir, valacyclovir/Valtrex -IV infuse slowly, hydrate
interventions/nursing actions -monitor GI issues
-monitor severe skin reactions
-wear gloves


acyclovir, valacyclovir/Valtrex client -report CNS tox signs
instructions -report IV site irritation
-continue condom usage
-take with food
-prep for IV hydration


amoxicillin (ampicillin, piperacillin, -broad spectrum antibiotic: infections of the soft
pen G) indications for use tissues (throat, ear)
-narrow spectrum (UTI)


amoxicillin (ampicillin, piperacillin, damages cell wall (but not cell wall of the host)
pen G) mechanism of action


amoxicillin (ampicillin, piperacillin, -most common med allergy
pen G) ADRs -superinfections


amoxicillin (ampicillin, piperacillin, -monitor GI symptoms
pen G) interventions/nursing actions -bloody stools might be C.Diff
-monitor for candida
-be careful with Pen G IV admin


amoxicillin (ampicillin, piperacillin, -take with food
pen G) client instructions -be sure to finish all medication
-monitor for allergy
-bloody diarrhea: report immediately
-airway concerns call 911


cephalexin, ceftriaxone, cefepime broad spectrum, many generations- useful with
indications for use meningitis

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