HESI A2 Reading Comprehension V2
Exam (Latest 2026/2027 Update)
Complete Q&A with Verified Answers
and Detailed Rationales Passage-Based
HESI A2 Reading Comprehension V2 Exam (Latest |
Comprehensive Examination
HESI A2 Reading Comprehension V2 Exam (Latest
2026/2027 Update) Complete Q&A with Verified Answers and
Detailed Rationales Passage-Based Questions, Main Idea,
INTRODUCTION
This document is an important and very helpful preparation
resource for HESI A2 Reading Comprehension V2 Exam
(Latest 2026/2027 Update) Complete Q&A with Verified
Answers and Detailed Rationales Passage-Based Questions,
Main Idea, Vocabulary in Context, Inference A+ Graded. Every
item uses a focused exam stem, four response options, a keyed
response, and a clear rationale, making it easier to understand
the subject, spot distractors, and build real exam confidence.
Page 1
, Question 1
Read the following passage and determine the main idea:
"Recent advances in genomic sequencing have dramatically reduced the cost of
identifying hereditary cancer syndromes. However, the widespread availability
of genetic testing has outpaced the development of standardized protocols for
interpreting variants of uncertain significance. As a result, clinicians frequently
face the dilemma of whether to recommend prophylactic interventions based
on incomplete data. This gap between technological capability and clinical
guidance represents one of the most pressing ethical challenges in modern
oncology."
Which statement best expresses the main idea of the passage?
A. Genomic sequencing costs have decreased significantly in recent
years.
B. Variants of uncertain significance are the most common result of
genetic testing.
C. The gap between genetic testing technology and clinical interpretation
guidelines creates a significant ethical dilemma in oncology.
D. Prophylactic interventions should not be recommended based on
genetic testing alone.
Correct Answer: C - The gap between genetic testing technology
and clinical interpretation guidelines creates a significant ethical
dilemma in oncology.
RATIONALE
The passage's central claim is that technological capability has
outpaced clinical guidance, creating an ethical challenge. Option A is
a supporting detail, not the main idea. Option B is not stated in the
passage. Option D is an inference not directly supported and is too
absolute.
Page 2
, Question 2
Read the passage and answer the question:
"The nurse's note read: 'Patient exhibits labile affect, alternating between
tearfulness and irritability within minutes. Denies suicidal ideation but
expresses hopelessness about recovery.'"
As used in the passage, the word "labile" most nearly means:
A. Stable and predictable
B. Rapidly changing and unstable
C. Excessively cheerful
D. Withdrawn and unresponsive
Correct Answer: B - Rapidly changing and unstable
RATIONALE
The context-alternating between tearfulness and irritability within
minutes-indicates rapid fluctuation. 'Labile' in clinical usage means
rapidly changing or unstable. The other options contradict the context
or describe unrelated states.
Page 3
, Question 3
Read the passage and answer the question:
"Despite the surgeon's meticulous technique, the patient developed a
postoperative infection. The wound culture grew methicillin-resistant
Staphylococcus aureus (MRSA). The infection control team noted that the
patient had been colonized with MRSA prior to admission, a fact documented
in the electronic health record but not communicated during the surgical
timeout."
Which of the following can be reasonably inferred from the passage?
A. The surgeon's technique was the primary cause of the infection.
B. The infection was unavoidable regardless of communication.
C. A breakdown in communication during the surgical timeout may have
contributed to the infection.
D. The patient acquired MRSA during the hospital stay.
Correct Answer: C - A breakdown in communication during the
surgical timeout may have contributed to the infection.
RATIONALE
The passage states that the MRSA colonization was documented but
not communicated during the timeout, implying a communication gap
that may have contributed to the infection. Option A contradicts the
passage's emphasis on the surgeon's meticulous technique. Option B is
not supported. Option D contradicts the fact that colonization was
present prior to admission.
Page 4
Exam (Latest 2026/2027 Update)
Complete Q&A with Verified Answers
and Detailed Rationales Passage-Based
HESI A2 Reading Comprehension V2 Exam (Latest |
Comprehensive Examination
HESI A2 Reading Comprehension V2 Exam (Latest
2026/2027 Update) Complete Q&A with Verified Answers and
Detailed Rationales Passage-Based Questions, Main Idea,
INTRODUCTION
This document is an important and very helpful preparation
resource for HESI A2 Reading Comprehension V2 Exam
(Latest 2026/2027 Update) Complete Q&A with Verified
Answers and Detailed Rationales Passage-Based Questions,
Main Idea, Vocabulary in Context, Inference A+ Graded. Every
item uses a focused exam stem, four response options, a keyed
response, and a clear rationale, making it easier to understand
the subject, spot distractors, and build real exam confidence.
Page 1
, Question 1
Read the following passage and determine the main idea:
"Recent advances in genomic sequencing have dramatically reduced the cost of
identifying hereditary cancer syndromes. However, the widespread availability
of genetic testing has outpaced the development of standardized protocols for
interpreting variants of uncertain significance. As a result, clinicians frequently
face the dilemma of whether to recommend prophylactic interventions based
on incomplete data. This gap between technological capability and clinical
guidance represents one of the most pressing ethical challenges in modern
oncology."
Which statement best expresses the main idea of the passage?
A. Genomic sequencing costs have decreased significantly in recent
years.
B. Variants of uncertain significance are the most common result of
genetic testing.
C. The gap between genetic testing technology and clinical interpretation
guidelines creates a significant ethical dilemma in oncology.
D. Prophylactic interventions should not be recommended based on
genetic testing alone.
Correct Answer: C - The gap between genetic testing technology
and clinical interpretation guidelines creates a significant ethical
dilemma in oncology.
RATIONALE
The passage's central claim is that technological capability has
outpaced clinical guidance, creating an ethical challenge. Option A is
a supporting detail, not the main idea. Option B is not stated in the
passage. Option D is an inference not directly supported and is too
absolute.
Page 2
, Question 2
Read the passage and answer the question:
"The nurse's note read: 'Patient exhibits labile affect, alternating between
tearfulness and irritability within minutes. Denies suicidal ideation but
expresses hopelessness about recovery.'"
As used in the passage, the word "labile" most nearly means:
A. Stable and predictable
B. Rapidly changing and unstable
C. Excessively cheerful
D. Withdrawn and unresponsive
Correct Answer: B - Rapidly changing and unstable
RATIONALE
The context-alternating between tearfulness and irritability within
minutes-indicates rapid fluctuation. 'Labile' in clinical usage means
rapidly changing or unstable. The other options contradict the context
or describe unrelated states.
Page 3
, Question 3
Read the passage and answer the question:
"Despite the surgeon's meticulous technique, the patient developed a
postoperative infection. The wound culture grew methicillin-resistant
Staphylococcus aureus (MRSA). The infection control team noted that the
patient had been colonized with MRSA prior to admission, a fact documented
in the electronic health record but not communicated during the surgical
timeout."
Which of the following can be reasonably inferred from the passage?
A. The surgeon's technique was the primary cause of the infection.
B. The infection was unavoidable regardless of communication.
C. A breakdown in communication during the surgical timeout may have
contributed to the infection.
D. The patient acquired MRSA during the hospital stay.
Correct Answer: C - A breakdown in communication during the
surgical timeout may have contributed to the infection.
RATIONALE
The passage states that the MRSA colonization was documented but
not communicated during the timeout, implying a communication gap
that may have contributed to the infection. Option A contradicts the
passage's emphasis on the surgeon's meticulous technique. Option B is
not supported. Option D contradicts the fact that colonization was
present prior to admission.
Page 4
