TEST BANK FOR Psychopharmacology : drugs,the brain and behaviour 4th edition by Jerry Meyer ISBN:978-1605359878 COMPLETE GUIDE 100% VERIFIED A+ GRADE ASSURED!!!!NEW LATEST UPDATE!!!!!

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, Chapter 1: Principles of Pharmacology fk fk fk fk




Multiple Choice fk




1. fk


refer(s) to specific molecular changes that occur when a drug binds to a particular targ
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et site or receptor, while
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are the resulting widespread alterationsin function.
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a. Drug action; therapeutic effects fk fk fk



b. Side effects; drug effects fk fk fk



c. Therapeutic effects; side effects fk fk fk



d. Drug action; drug effects fk fk fk



Answer: d fk



Textbook Reference: Pharmacology: The Science of Drug Action
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2. After drug administration has occurred, the amount of drug in the blood that is free tobi
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nd at specific target sites is referred to as
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a. the therapeutic dose.
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b. first-pass effects. fk



c. bioavailability.
d. ED50.
Answer: c fk



Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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3. The specific molecular changes that occur when a drug binds to a particular target siteo
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r receptor are referred to as
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a. drug effects. fk



b. drug action. fk



c. side effects. fk



d. placebo effects. fk



Answer: b fk



Textbook Reference: Pharmacology: The Science of Drug Action
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4. Which of the following is not a possible explanation for placebo effects?
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a. Pavlovian conditioning fk



b. Genetic variation fk



c. Drug competition fk



d. Expectation of outcome fk fk



Answer: c fk



Textbook Reference: Pharmacology: The Science of Drug Action
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,5. The administration of oxytocin has been proposed as a treatment for autism. fk fk fk fk fk fk fk fk fk fk



a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer: c fk



Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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6. Which factor does not affect the pharmacokinetics of a drug?
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a. Route of administration
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b. Lipid solubility
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c. Depot binding fk



d. Drug action fk



Answer: d fk



Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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7. First-pass metabolism occurs when drugs are taken
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a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer: a fk



Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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8. The area postrema is one area in the brain where the
fk fk is not complete. fk fk fk fk fk fk fk fk fk fk



a. cerebrospinal fluid fk



b. blood–brain barrier fk



c. choroid plexus fk



d. phospholipid membrane fk



Answer: b fk



Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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9. First-pass metabolism occurs with orally administered drugs because
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a. their absorption is slowed by food.
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b. drugs absorbed into the bloodstream from the stomach go to the liver on the way tog
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eneral circulation.
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c. drugs must first survive the acidic environment of the stomach.
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d. salivary enzymes in the mouth begin the process of metabolism.
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Answer: b fk



Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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10. Toxic substances in the blood trigger a vomiting response by activating the
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a. blood–brain barrier. fk



b. choroid plexus. fk



c. area postrema.
fk



d. median eminence. fk




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, Answer: c fk



Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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11. Drugs administered _ have the most rapid onset of action.
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a. subcutaneously
b. intramuscularly
c. orally
d. intravenously
Answer: d fk



Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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12. Ionization of a drug depends on the of the solution and the
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of thedrug.
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a. pH; pKafk



b. pKa; pH fk



c. concentration; lipid solubility fk fk



d. pH; concentration
fk



Answer: a fk



Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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13. The absorption of a drug depends on all of the following except
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a. lipid solubility.
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b. ionization.
c. body temperature. fk



d. the concentration of the drug.
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Answer: c fk



Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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14. Drugs that are should be avoided by women of childbearing age.
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a. teratogenic
b. able to cross the placental barrier
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c. psychoactive
d. highly lipid-soluble fk



Answer: a fk



Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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15. Agents that induce developmental abnormalities in a fetus are known as
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a. psychoactive drugs. fk



b. illicit drugs. fk



c. teratogens.
d. placental drugs. fk



Answer: c fk



Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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16. Depot binding is said to occur when drugs
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a. bind to their target sites.
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