HESI LPN-ADN ENTRANCE
EXAM 2026/2027
QUESTIONS AND ANSWERS ALREADY
GRADED A+
100% VERIFIED SOLUTIONS | UPDATED PER
LATEST GUIDELINES | GRADED A+
DESCRIPTION
This comprehensive practice exam extract is drawn from
verified HESI A2 (Admission Assessment) question banks
aligned with the 2026/2027 Elsevier HESI testing blueprint. The
HESI A2 is the standardized entrance examination used by
nursing programs to assess academic readiness for admission to
LPN-to-ADN bridge programs, traditional ADN programs, and
BSN programs .
,The HESI A2 covers seven core subject areas: Mathematics,
Reading Comprehension, Vocabulary and General Knowledge,
Grammar, Biology, Chemistry, and Anatomy & Physiology .
Passing scores vary by program, but most require a minimum of
75% overall average across scored sections . Scores are valid
for three to five years depending on the institution .
SECTION 1: ANATOMY & PHYSIOLOGY
Question 1
What are the two most abundant minerals stored in the
extracellular matrix of bone?
A) Sodium and potassium
B) Calcium and phosphate
C) Magnesium and iron
D) Zinc and copper
Answer: B
Rationale: Calcium and phosphate are the two most abundant
minerals stored in the bone extracellular matrix. These minerals
provide strength and rigidity to the bone structure .
Question 2
,Where can the urinary bladder and internal reproductive
organs be found?
A) Thoracic cavity
B) Mediastinum
C) Abdominal cavity
D) Pelvic cavity
Answer: D
Rationale: The urinary bladder and internal reproductive
organs are located in the pelvic cavity, which is the most
inferior portion of the abdominopelvic cavity .
Question 3
Which set of valves is primarily responsible for preventing
blood flow from major blood vessels back into the heart?
A) Atrioventricular valves
B) Semilunar valves
C) Mitral valve
D) Tricuspid valve
Answer: B
Rationale: The semilunar valves (pulmonary and aortic valves)
prevent backflow of blood from the major blood vessels
(pulmonary artery and aorta) into the heart's ventricles .
, Question 4
What is the most abundant type of glial cell in the central
nervous system that anchors neurons to capillaries and helps
control the environment around neurons?
A) Oligodendrocytes
B) Microglia
C) Astrocytes
D) Ependymal cells
Answer: C
Rationale: Astrocytes are the most abundant glial cells in the
CNS. They anchor neurons to capillaries and help maintain the
blood-brain barrier and control the extracellular environment
around neurons .
Question 5
The pancreas is an endocrine gland mainly responsible for
which of the following?
A) Producing digestive enzymes
B) Maintaining healthy blood sugar levels
C) Producing red blood cells
D) Filtering blood
Answer: B
EXAM 2026/2027
QUESTIONS AND ANSWERS ALREADY
GRADED A+
100% VERIFIED SOLUTIONS | UPDATED PER
LATEST GUIDELINES | GRADED A+
DESCRIPTION
This comprehensive practice exam extract is drawn from
verified HESI A2 (Admission Assessment) question banks
aligned with the 2026/2027 Elsevier HESI testing blueprint. The
HESI A2 is the standardized entrance examination used by
nursing programs to assess academic readiness for admission to
LPN-to-ADN bridge programs, traditional ADN programs, and
BSN programs .
,The HESI A2 covers seven core subject areas: Mathematics,
Reading Comprehension, Vocabulary and General Knowledge,
Grammar, Biology, Chemistry, and Anatomy & Physiology .
Passing scores vary by program, but most require a minimum of
75% overall average across scored sections . Scores are valid
for three to five years depending on the institution .
SECTION 1: ANATOMY & PHYSIOLOGY
Question 1
What are the two most abundant minerals stored in the
extracellular matrix of bone?
A) Sodium and potassium
B) Calcium and phosphate
C) Magnesium and iron
D) Zinc and copper
Answer: B
Rationale: Calcium and phosphate are the two most abundant
minerals stored in the bone extracellular matrix. These minerals
provide strength and rigidity to the bone structure .
Question 2
,Where can the urinary bladder and internal reproductive
organs be found?
A) Thoracic cavity
B) Mediastinum
C) Abdominal cavity
D) Pelvic cavity
Answer: D
Rationale: The urinary bladder and internal reproductive
organs are located in the pelvic cavity, which is the most
inferior portion of the abdominopelvic cavity .
Question 3
Which set of valves is primarily responsible for preventing
blood flow from major blood vessels back into the heart?
A) Atrioventricular valves
B) Semilunar valves
C) Mitral valve
D) Tricuspid valve
Answer: B
Rationale: The semilunar valves (pulmonary and aortic valves)
prevent backflow of blood from the major blood vessels
(pulmonary artery and aorta) into the heart's ventricles .
, Question 4
What is the most abundant type of glial cell in the central
nervous system that anchors neurons to capillaries and helps
control the environment around neurons?
A) Oligodendrocytes
B) Microglia
C) Astrocytes
D) Ependymal cells
Answer: C
Rationale: Astrocytes are the most abundant glial cells in the
CNS. They anchor neurons to capillaries and help maintain the
blood-brain barrier and control the extracellular environment
around neurons .
Question 5
The pancreas is an endocrine gland mainly responsible for
which of the following?
A) Producing digestive enzymes
B) Maintaining healthy blood sugar levels
C) Producing red blood cells
D) Filtering blood
Answer: B
