Nur 670 - Apea Pmhnp Exam And Practice Exam Newest 2026/ 2027
Test Bank| Nur670 Pmhnp - Apea Exam Prep With Complete 300 Real
Exam Questions And Correct Verified Answers/ Already Graded A+
(Most Recent!!)
Questions 1–300 | 2026/2027 Study Edition
1. A patient with major depressive disorder reports depressed mood,
anhedonia, insomnia, fatigue, and feelings of worthlessness for 3
weeks. Which diagnosis is most appropriate?
A. Bipolar I disorder
B. Major depressive disorder
C. Cyclothymic disorder
D. Adjustment disorder
Answer: B. The patient has multiple depressive symptoms lasting at
least 2 weeks with clinically significant impairment.
2. Which neurotransmitter is most strongly associated with mood
regulation and is a primary target of SSRIs?
A. Acetylcholine
B. Serotonin
C. Histamine
D. GABA
Answer: B. SSRIs increase serotonergic neurotransmission by inhibiting
serotonin reuptake.
3. Which medication is a selective serotonin reuptake inhibitor?
A. Sertraline
B. Lithium
C. Lamotrigine
D. Quetiapine
,Answer: A. Sertraline is an SSRI commonly used for depressive and
anxiety disorders.
4. A patient taking sertraline reports nausea during the first week. What
is the best response?
A. Stop the medication immediately
B. Explain that mild GI effects can occur early and often improve
C. Double the dose
D. Add lithium
Answer: B. GI adverse effects are common early with SSRIs and
frequently diminish with continued treatment.
5. Which symptom requires the most immediate assessment in a
patient with depression?
A. Fatigue
B. Decreased appetite
C. Suicidal intent with a specific plan
D. Mild insomnia
Answer: C. Active suicidal intent and a specific plan require immediate
safety assessment and intervention.
6. Which question is most appropriate when assessing suicide risk?
A. “You aren't thinking about suicide, are you?”
B. “Have you had thoughts of killing yourself?”
C. “Why would you do that?”
D. “Your family would be devastated, right?”
Answer: B. Direct, nonjudgmental questioning is appropriate and does
not increase suicide risk.
7. Which finding represents suicidal intent rather than passive suicidal
ideation?
,A. “I wish I wouldn't wake up.”
B. “Life isn't worth living.”
C. “I have decided how and when I will kill myself.”
D. “I feel hopeless.”
Answer: C. A specific method, timing, and intent indicate substantially
greater acute risk.
8. Which medication class is generally first-line pharmacotherapy for
generalized anxiety disorder?
A. SSRIs/SNRIs
B. Stimulants
C. Typical antipsychotics
D. Anticholinergics
Answer: A. SSRIs and SNRIs are commonly first-line long-term
pharmacologic treatments for GAD.
9. A patient taking an SSRI develops agitation, diaphoresis, diarrhea,
hyperreflexia, and clonus. What should the PMHNP suspect?
A. Neuroleptic malignant syndrome
B. Serotonin syndrome
C. Lithium toxicity
D. Anticholinergic toxicity
Answer: B. Hyperreflexia, clonus, autonomic activation, and GI
symptoms strongly suggest serotonin toxicity.
10. Which combination creates a particularly significant serotonin-
syndrome risk?
A. SSRI plus MAOI
B. SSRI plus calcium carbonate
C. SSRI plus acetaminophen
, D. SSRI plus topical moisturizer
Answer: A. Combining serotonergic antidepressants with MAOIs can
produce potentially life-threatening serotonin toxicity.
11. What is the typical minimum duration required for diagnosing a
major depressive episode?
A. 24 hours
B. 3 days
C. 1 week
D. 2 weeks
Answer: D. DSM-based diagnosis requires symptoms persisting for at
least 2 weeks.
12. Which symptom is characteristic of mania?
A. Psychomotor retardation
B. Decreased need for sleep
C. Anhedonia
D. Excessive guilt
Answer: B. Decreased need for sleep is a classic manic symptom.
13. Which diagnosis requires at least one lifetime manic episode?
A. Bipolar I disorder
B. Bipolar II disorder
C. Persistent depressive disorder
D. Cyclothymic disorder
Answer: A. Bipolar I disorder is defined by the occurrence of mania.
14. Bipolar II disorder requires which combination?
A. Mania and psychosis
B. Hypomania and major depressive episodes
C. Mania only
Test Bank| Nur670 Pmhnp - Apea Exam Prep With Complete 300 Real
Exam Questions And Correct Verified Answers/ Already Graded A+
(Most Recent!!)
Questions 1–300 | 2026/2027 Study Edition
1. A patient with major depressive disorder reports depressed mood,
anhedonia, insomnia, fatigue, and feelings of worthlessness for 3
weeks. Which diagnosis is most appropriate?
A. Bipolar I disorder
B. Major depressive disorder
C. Cyclothymic disorder
D. Adjustment disorder
Answer: B. The patient has multiple depressive symptoms lasting at
least 2 weeks with clinically significant impairment.
2. Which neurotransmitter is most strongly associated with mood
regulation and is a primary target of SSRIs?
A. Acetylcholine
B. Serotonin
C. Histamine
D. GABA
Answer: B. SSRIs increase serotonergic neurotransmission by inhibiting
serotonin reuptake.
3. Which medication is a selective serotonin reuptake inhibitor?
A. Sertraline
B. Lithium
C. Lamotrigine
D. Quetiapine
,Answer: A. Sertraline is an SSRI commonly used for depressive and
anxiety disorders.
4. A patient taking sertraline reports nausea during the first week. What
is the best response?
A. Stop the medication immediately
B. Explain that mild GI effects can occur early and often improve
C. Double the dose
D. Add lithium
Answer: B. GI adverse effects are common early with SSRIs and
frequently diminish with continued treatment.
5. Which symptom requires the most immediate assessment in a
patient with depression?
A. Fatigue
B. Decreased appetite
C. Suicidal intent with a specific plan
D. Mild insomnia
Answer: C. Active suicidal intent and a specific plan require immediate
safety assessment and intervention.
6. Which question is most appropriate when assessing suicide risk?
A. “You aren't thinking about suicide, are you?”
B. “Have you had thoughts of killing yourself?”
C. “Why would you do that?”
D. “Your family would be devastated, right?”
Answer: B. Direct, nonjudgmental questioning is appropriate and does
not increase suicide risk.
7. Which finding represents suicidal intent rather than passive suicidal
ideation?
,A. “I wish I wouldn't wake up.”
B. “Life isn't worth living.”
C. “I have decided how and when I will kill myself.”
D. “I feel hopeless.”
Answer: C. A specific method, timing, and intent indicate substantially
greater acute risk.
8. Which medication class is generally first-line pharmacotherapy for
generalized anxiety disorder?
A. SSRIs/SNRIs
B. Stimulants
C. Typical antipsychotics
D. Anticholinergics
Answer: A. SSRIs and SNRIs are commonly first-line long-term
pharmacologic treatments for GAD.
9. A patient taking an SSRI develops agitation, diaphoresis, diarrhea,
hyperreflexia, and clonus. What should the PMHNP suspect?
A. Neuroleptic malignant syndrome
B. Serotonin syndrome
C. Lithium toxicity
D. Anticholinergic toxicity
Answer: B. Hyperreflexia, clonus, autonomic activation, and GI
symptoms strongly suggest serotonin toxicity.
10. Which combination creates a particularly significant serotonin-
syndrome risk?
A. SSRI plus MAOI
B. SSRI plus calcium carbonate
C. SSRI plus acetaminophen
, D. SSRI plus topical moisturizer
Answer: A. Combining serotonergic antidepressants with MAOIs can
produce potentially life-threatening serotonin toxicity.
11. What is the typical minimum duration required for diagnosing a
major depressive episode?
A. 24 hours
B. 3 days
C. 1 week
D. 2 weeks
Answer: D. DSM-based diagnosis requires symptoms persisting for at
least 2 weeks.
12. Which symptom is characteristic of mania?
A. Psychomotor retardation
B. Decreased need for sleep
C. Anhedonia
D. Excessive guilt
Answer: B. Decreased need for sleep is a classic manic symptom.
13. Which diagnosis requires at least one lifetime manic episode?
A. Bipolar I disorder
B. Bipolar II disorder
C. Persistent depressive disorder
D. Cyclothymic disorder
Answer: A. Bipolar I disorder is defined by the occurrence of mania.
14. Bipolar II disorder requires which combination?
A. Mania and psychosis
B. Hypomania and major depressive episodes
C. Mania only
