| Portage Learning
These are original, instructor-style practice questions written for study. They are not
official Portage Learning questions and are not copied from any exam, textbook, or
question bank. They align with common BIOD 101 Module 6 biology topics, especially
the cardiovascular and lymphatic systems, with NCLEX-style clinical framing.
Question 1:
Which blood component primarily transports oxygen?
A. Plasma
B. Erythrocytes
C. Leukocytes
D. Platelets
Correct answer: B
Rationale: Erythrocytes contain hemoglobin, which carries oxygen.
Question 2:
Which blood component defends the body against infection?
A. Erythrocytes
B. Leukocytes
C. Platelets
D. Plasma proteins
Correct answer: B
Rationale: Leukocytes are white blood cells that provide immune defense.
Question 3:
Which blood component is most directly responsible for clot formation?
A. Erythrocytes
B. Leukocytes
C. Platelets
D. Albumin
Correct answer: C
Rationale: Platelets form the initial plug during hemostasis.
,Question 4:
Which plasma protein is most important for maintaining osmotic pressure?
A. Albumin
B. Fibrinogen
C. Globulin
D. Thrombin
Correct answer: A
Rationale: Albumin pulls water into the bloodstream and maintains osmotic pressure.
Question 5:
Which formed element lacks a nucleus in mature form?
A. Neutrophil
B. Erythrocyte
C. Lymphocyte
D. Monocyte
Correct answer: B
Rationale: Mature erythrocytes lose their nucleus to carry more hemoglobin.
Question 6:
Where does hematopoiesis primarily occur in adults?
A. Liver
B. Spleen
C. Red bone marrow
D. Thymus
Correct answer: C
Rationale: Red bone marrow is the primary site of blood cell production in adults.
Question 7:
Which hormone stimulates red blood cell production?
A. Insulin
B. Erythropoietin
C. Thyroxine
D. Cortisol
Correct answer: B
Rationale: Erythropoietin, released by the kidneys, stimulates erythropoiesis.
, Question 8:
Iron deficiency anemia typically produces which red blood cell appearance?
A. Macrocytic
B. Microcytic and hypochromic
C. Sickle-shaped
D. Spherical
Correct answer: B
Rationale: Iron deficiency causes small, pale red blood cells.
Question 9:
Vitamin B12 deficiency anemia is associated with which finding?
A. Microcytic cells
B. Macrocytic cells and neurologic symptoms
C. Sickle cells
D. Increased platelets
Correct answer: B
Rationale: B12 deficiency causes megaloblastic anemia and neurologic changes.
Question 10:
Sickle cell disease is caused by abnormal:
A. Hemoglobin
B. Albumin
C. Fibrinogen
D. Platelets
Correct answer: A
Rationale: Abnormal hemoglobin S causes red blood cells to sickle.
Question 11:
Which blood type is considered the universal donor for red blood cells?
A. A positive
B. B negative
C. AB positive
D. O negative
Correct answer: D
Rationale: O negative lacks A, B, and Rh antigens.