PSIO 431 IMMUNOLOGY EXAM QUESTIONS UPDATED
ACTUAL QUESTIONS AND CORRECT ANSWERS
Question:
1. Toll-like receptors:
a. are pathogen-associated molecular patterns
b. are damage-associated molecular patterns
c. are expressed only on B cells, macrophages and dendritic cells
d. are pattern-recognition receptors
Answer:
d. are pattern-recognition receptors
Question:
2. The clotting cascade is an important part of adaptive immunity
true false
Answer:
false
Question:
3. A circulating lymphocyte from the blood enters the lymph-node, then exits out of the ___ and enters
the ___ before entering the blood stream again
a. efferent lymph; postcapillary venules
b. efferent lymph; thoracic duct
c. afferent lymph; efferent lymph
d. afferent lymph; thoracic duct
Answer:
b. efferent lymph; thoracic duct
Question:
4. The Fc component of antibody is important for all EX- CEPT . . .
a. phagocyte binding
b. complement binding
c. antigen binding
d. mast cell degranulation
Answer:
c. antigen binding
Question:
5. Select the immunoglobulin class to which the statement best applies:
1. IgA (secreted)
2. IgG
3. IgM
4. IgD
5. IgE
a. the class whose Fc portion binds to mast cells and basophils
b. the class of antibody that is associated with secretory factor
c. if you had 1 uM solutions of each class, the solution of this class would be the most viscous
,Answer:
a. 5. IgE
b. 1. IgA (secreted)
c. 3. IgM
Question:
6. A lymphoblast is an activated ___ cell
a. T
b. macrophage
c. both T and B
d. B
Answer:
c. both T and B
Question:
7. An antigen ALWAYS causes an immune response true false
Answer:
false
Question:
8. Apart from lymphocytes, which type makes up the HIGHEST percentage of white cells in the blood
in adults?
a. eosinophils
b. neutrophils
c. basophils
d. monocytes
Answer:
b. neutrophils
Question:
9. Redness associated with inflammation is due indirectly to mast cell degranulation
true false
Answer:
true
Question:
10. My preparation for IgG anti-Streptococcus, which used to agglutinate the bacteria very effectively,
has been tampered with by my evil graduate student! Now I find that what's in the tube binds
specifically to Streptococcus, but there is no agglutination. I think that what I have now is:
a. IgM
b. F(ab)2
c. aged complement
d. Fab
e. Fc
Answer:
d. Fab
, Question:
11. A molecule called HSP-70 is released by injured cells, and causes inflammation by stimulating
TLR-2. Based on these findings, what is HSP-70?
a. it is a TLR
b. it is a DAMP
c. it is a PAMP
d. it is a PRR
Answer:
b. it is a DAMP
Question:
12. After an innate immune response has taken place, what is the cell that is considered to be the
bridge between innate and adaptive immunity called?
a. a dendritic cell
b. an endothelial cell
c. a macrophage
d. a B-cell
Answer:
a. a dendritic cell
Question:
13. Which of the following explains WHY we see swelling during acute inflammation?
a. increased stimulation of nerve endings
b. increased leakiness of blood vessels
c. increased blood flow to the area
d. increased clotting
Answer:
b. increased leakiness of blood vessels
Question:
14. What is special about the Lectin Complement Pathway?
a. it can be activated by either: with antibody or without antibody
b. it is only found in humans
c. it is purely part of the innate immune system
d. it is purely part of the adaptive immune system
Answer:
c. it is purely part of the innate immune system
Question:
15. What is opsonization?
a. binding of substances to bacteria to make it more attractive to phagocytes
b. binding of substances to bacteria that help it hide from phagocytes
c. sugars that coat the outside of bacteria
d. the way cells "call" other cells toward them
Answer:
a. binding of substances to bacteria to make it more attractive to phagocytes
ACTUAL QUESTIONS AND CORRECT ANSWERS
Question:
1. Toll-like receptors:
a. are pathogen-associated molecular patterns
b. are damage-associated molecular patterns
c. are expressed only on B cells, macrophages and dendritic cells
d. are pattern-recognition receptors
Answer:
d. are pattern-recognition receptors
Question:
2. The clotting cascade is an important part of adaptive immunity
true false
Answer:
false
Question:
3. A circulating lymphocyte from the blood enters the lymph-node, then exits out of the ___ and enters
the ___ before entering the blood stream again
a. efferent lymph; postcapillary venules
b. efferent lymph; thoracic duct
c. afferent lymph; efferent lymph
d. afferent lymph; thoracic duct
Answer:
b. efferent lymph; thoracic duct
Question:
4. The Fc component of antibody is important for all EX- CEPT . . .
a. phagocyte binding
b. complement binding
c. antigen binding
d. mast cell degranulation
Answer:
c. antigen binding
Question:
5. Select the immunoglobulin class to which the statement best applies:
1. IgA (secreted)
2. IgG
3. IgM
4. IgD
5. IgE
a. the class whose Fc portion binds to mast cells and basophils
b. the class of antibody that is associated with secretory factor
c. if you had 1 uM solutions of each class, the solution of this class would be the most viscous
,Answer:
a. 5. IgE
b. 1. IgA (secreted)
c. 3. IgM
Question:
6. A lymphoblast is an activated ___ cell
a. T
b. macrophage
c. both T and B
d. B
Answer:
c. both T and B
Question:
7. An antigen ALWAYS causes an immune response true false
Answer:
false
Question:
8. Apart from lymphocytes, which type makes up the HIGHEST percentage of white cells in the blood
in adults?
a. eosinophils
b. neutrophils
c. basophils
d. monocytes
Answer:
b. neutrophils
Question:
9. Redness associated with inflammation is due indirectly to mast cell degranulation
true false
Answer:
true
Question:
10. My preparation for IgG anti-Streptococcus, which used to agglutinate the bacteria very effectively,
has been tampered with by my evil graduate student! Now I find that what's in the tube binds
specifically to Streptococcus, but there is no agglutination. I think that what I have now is:
a. IgM
b. F(ab)2
c. aged complement
d. Fab
e. Fc
Answer:
d. Fab
, Question:
11. A molecule called HSP-70 is released by injured cells, and causes inflammation by stimulating
TLR-2. Based on these findings, what is HSP-70?
a. it is a TLR
b. it is a DAMP
c. it is a PAMP
d. it is a PRR
Answer:
b. it is a DAMP
Question:
12. After an innate immune response has taken place, what is the cell that is considered to be the
bridge between innate and adaptive immunity called?
a. a dendritic cell
b. an endothelial cell
c. a macrophage
d. a B-cell
Answer:
a. a dendritic cell
Question:
13. Which of the following explains WHY we see swelling during acute inflammation?
a. increased stimulation of nerve endings
b. increased leakiness of blood vessels
c. increased blood flow to the area
d. increased clotting
Answer:
b. increased leakiness of blood vessels
Question:
14. What is special about the Lectin Complement Pathway?
a. it can be activated by either: with antibody or without antibody
b. it is only found in humans
c. it is purely part of the innate immune system
d. it is purely part of the adaptive immune system
Answer:
c. it is purely part of the innate immune system
Question:
15. What is opsonization?
a. binding of substances to bacteria to make it more attractive to phagocytes
b. binding of substances to bacteria that help it hide from phagocytes
c. sugars that coat the outside of bacteria
d. the way cells "call" other cells toward them
Answer:
a. binding of substances to bacteria to make it more attractive to phagocytes