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Genetics Exam 1 Key Concepts And Practice Questions

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Genetics Exam 1 Key Concepts And Practice Questions

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GENETICS EXAM 1 KEY CONCEPTS AND
PRACTICE QUESTIONS

◉ proband?
Answer: affected person first identified in family


◉ consultand?
Answer: person seeking genetic evaluation


◉ sibs/sibship?
Answer: brothers and sisters


◉ first degree relatives?
Answer: parents, siblings, children


◉ second degree relatives?
Answer: grandparents, grandchildren, aunts/uncles,
nieces/nephews, half-sibs


◉ third degree relatives?
Answer: first cousins

,◉ consanguineous?
Answer: partners sharing a common ancestor


◉ which side goes on pedigree?
Answer: left = father; right = mother


◉ arrow on pedigree points to?
Answer: proband


◉ chromosome?
Answer: DNA organized into rod-shaped structures


◉ how many genes in body?
Answer: ~25,000


◉ genes?
Answer: functional units of heredity


◉ how long is DNA?
Answer: ~6 feet

, ◉ when are chromosomes best seen?
Answer: prophase & metaphase


◉ what part of cell has its own genome?
Answer: mitochondria


◉ how many genes in mitochondrial genome?
Answer: 37


◉ mitochondrial genome encodes?
Answer: proteins for oxidative phosphorylation


◉ mitochondrial DNA inheritance?
Answer: maternal


◉ locus?
Answer: specific DNA position on a chromosome


◉ alleles?
Answer: alternative versions of a gene


◉ DNA dosage?

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