ANCC FNP Board Exam Newest 2026/2027 Actual
Exam| Ancc Family Nurse Practitioner (Fnp-Bc™)
Certification Exam With Complete 175 Real Exam
Questions And Correct Verified Answers/ Already
Graded A+
175 QUESTIONS
TABLE OF CONTENTS
# TOPIC
1 Cardiovascular
2 Respiratory
3 Endocrine
4 Gastroenterology
5 Musculoskeletal
6 Neurology
7 Psychiatry
8 Women's Health
9 Men's Health
10 Pediatrics
11 Dermatology
12 Renal/Urinary
13 Professional Practice
,Q1
A 54-year-old male with hypertension, diabetes, and smoking history presents with substernal
chest pressure radiating to the left arm. Which is the priority action?
A) Obtain a chest X-ray
B) Activate emergency services and obtain an ECG CORRECT
C) Prescribe nitroglycerin and discharge
D) Order an outpatient stress test
Rationale
Suspected acute coronary syndrome requires immediate ECG and emergency transfer; delay increases
mortality.
Q2
A 28-year-old female has dysuria, frequency, and suprapubic pain. Urinalysis shows nitrites and
leukocyte esterase. Which is the most likely diagnosis?
A) Pyelonephritis
B) Uncomplicated cystitis CORRECT
C) Nephrolithiasis
D) Vulvovaginitis
Rationale
Dysuria, frequency, and positive nitrites/leukocyte esterase indicate lower UTI without systemic signs.
Q3
A 67-year-old male with COPD has increased dyspnea, purulent sputum, and fever. Which
antibiotic is first-line for outpatient exacerbation without Pseudomonas risk?
A) Levofloxacin
B) Doxycycline CORRECT
2
,C) Amoxicillin
D) Azithromycin
Rationale
Mild-moderate COPD exacerbation without risk factors is treated with doxycycline, macrolide, or
amoxicillin-clavulanate.
Q4
A 45-year-old female has fatigue, weight gain, cold intolerance, and TSH 25 mIU/L. Which is the
best initial treatment?
A) Methimazole
B) Levothyroxine CORRECT
C) Liothyronine
D) Radioactive iodine
Rationale
Primary hypothyroidism is treated with levothyroxine; recheck TSH in 6–8 weeks.
Q5
A 62-year-old male has fasting glucose 130 mg/dL and A1c 7.4%. Which medication is first-line?
A) Glipizide
B) Metformin CORRECT
C) Insulin glargine
D) Pioglitazone
Rationale
Metformin is first-line for type 2 diabetes unless contraindicated; it lowers hepatic glucose production.
3
, Q6
A 30-year-old female has unilateral throbbing headache, photophobia, nausea, and visual aura.
Which acute treatment is most appropriate?
A) Propranolol
B) Sumatriptan CORRECT
C) Topiramate
D) Amitriptyline
Rationale
Triptans are first-line for acute moderate-severe migraine; avoid in CAD or uncontrolled hypertension.
Q7
A 72-year-old female has sudden severe headache, neck stiffness, and photophobia. Which is the
priority diagnostic test?
A) MRI brain
B) Non-contrast head CT CORRECT
C) Lumbar puncture without imaging
D) Carotid ultrasound
Rationale
Suspected subarachnoid hemorrhage requires immediate non-contrast CT; LP if CT negative and
suspicion remains.
Q8
A 55-year-old male has burning epigastric pain relieved by food, NSAID use, and guaiac-positive
stool. Which is the most likely diagnosis?
A) Gastric ulcer
B) Duodenal ulcer CORRECT
4
Exam| Ancc Family Nurse Practitioner (Fnp-Bc™)
Certification Exam With Complete 175 Real Exam
Questions And Correct Verified Answers/ Already
Graded A+
175 QUESTIONS
TABLE OF CONTENTS
# TOPIC
1 Cardiovascular
2 Respiratory
3 Endocrine
4 Gastroenterology
5 Musculoskeletal
6 Neurology
7 Psychiatry
8 Women's Health
9 Men's Health
10 Pediatrics
11 Dermatology
12 Renal/Urinary
13 Professional Practice
,Q1
A 54-year-old male with hypertension, diabetes, and smoking history presents with substernal
chest pressure radiating to the left arm. Which is the priority action?
A) Obtain a chest X-ray
B) Activate emergency services and obtain an ECG CORRECT
C) Prescribe nitroglycerin and discharge
D) Order an outpatient stress test
Rationale
Suspected acute coronary syndrome requires immediate ECG and emergency transfer; delay increases
mortality.
Q2
A 28-year-old female has dysuria, frequency, and suprapubic pain. Urinalysis shows nitrites and
leukocyte esterase. Which is the most likely diagnosis?
A) Pyelonephritis
B) Uncomplicated cystitis CORRECT
C) Nephrolithiasis
D) Vulvovaginitis
Rationale
Dysuria, frequency, and positive nitrites/leukocyte esterase indicate lower UTI without systemic signs.
Q3
A 67-year-old male with COPD has increased dyspnea, purulent sputum, and fever. Which
antibiotic is first-line for outpatient exacerbation without Pseudomonas risk?
A) Levofloxacin
B) Doxycycline CORRECT
2
,C) Amoxicillin
D) Azithromycin
Rationale
Mild-moderate COPD exacerbation without risk factors is treated with doxycycline, macrolide, or
amoxicillin-clavulanate.
Q4
A 45-year-old female has fatigue, weight gain, cold intolerance, and TSH 25 mIU/L. Which is the
best initial treatment?
A) Methimazole
B) Levothyroxine CORRECT
C) Liothyronine
D) Radioactive iodine
Rationale
Primary hypothyroidism is treated with levothyroxine; recheck TSH in 6–8 weeks.
Q5
A 62-year-old male has fasting glucose 130 mg/dL and A1c 7.4%. Which medication is first-line?
A) Glipizide
B) Metformin CORRECT
C) Insulin glargine
D) Pioglitazone
Rationale
Metformin is first-line for type 2 diabetes unless contraindicated; it lowers hepatic glucose production.
3
, Q6
A 30-year-old female has unilateral throbbing headache, photophobia, nausea, and visual aura.
Which acute treatment is most appropriate?
A) Propranolol
B) Sumatriptan CORRECT
C) Topiramate
D) Amitriptyline
Rationale
Triptans are first-line for acute moderate-severe migraine; avoid in CAD or uncontrolled hypertension.
Q7
A 72-year-old female has sudden severe headache, neck stiffness, and photophobia. Which is the
priority diagnostic test?
A) MRI brain
B) Non-contrast head CT CORRECT
C) Lumbar puncture without imaging
D) Carotid ultrasound
Rationale
Suspected subarachnoid hemorrhage requires immediate non-contrast CT; LP if CT negative and
suspicion remains.
Q8
A 55-year-old male has burning epigastric pain relieved by food, NSAID use, and guaiac-positive
stool. Which is the most likely diagnosis?
A) Gastric ulcer
B) Duodenal ulcer CORRECT
4
