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Exam (elaborations)

NRNP 6665 Final UPDATED ACTUAL Exam Questions and CORRECT Answers

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NRNP 6665 Final UPDATED ACTUAL Exam Questions and CORRECT Answers

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NRNP 6665 Final
UPDATED ACTUAL Exam Questions and CORRECT Answers

Question 1.
Agomelatine

Correct Answer: Brand: Valdoxan


Question 2.
-Melatonin multimodal (Mel-MM)


Question 3.
-Agonist at melatonergic 1 and melatonergic 2 receptors


Question 4.
-Antagonist at 5HT2C receptors


Question 5.
-Not FDA approved: Rx for Depression, Generalized anxiety disorder


Question 6.
-Initial 25 mg/day at bedtime; after 2 weeks can increase to 50 mg/day at bedtime


Question 7.
Amitriptyline (Elavil)

Correct Answer: Tricyclic antidepressant.


Question 8.
Aripiprazole (Abilify)

Correct Answer: Treatment for depression. Atypical antipsychotic. "Dopamine
stabilizer". Dopamine receptor antagonist in high concentration and also
stimulates increase of dopamine in low concentrations. Side effects: insomnia,
akathisia.


Question 9.
Brexpiprazole (Rexulti)

Correct Answer: Treatment for depression. Atypical antipsychotic

,Question 10.
Bupropion (Wellbutrin)

Correct Answer: Antidepressant and smoking cessation aid, It can treat
depression and help people quit smoking. It can also prevent depression
caused by seasonal affective disorder (SAD).


Question 11.
Citalopram (Celexa)

Correct Answer: Antidepressant, SSRI: 20-40 mg qd.


Question 12.
Clomipramine (Anafranil)

Correct Answer: -Serotonin reuptake inhibitor (S-RI) -Tricyclic antidepressant
(TCA)


Question 13.
-Parent drug is a potent serotonin reuptake inhibitor


Question 14.
Active metabolite is a potent norepinephrine/noradrenaline reuptake inhibitor


Question 15.
-Increases serotonergic neurotransmission by blocking the serotonin reuptake pump
(transporter), -Desensitization of serotonin receptors, especially serotonin 1A receptors


Question 16.
-Increases noradrenergic neurotransmission by blocking the norepinephrine reuptake
pump (transporter), -Desensitization of beta adrenergic receptors


Question 17.
-Dopamine is inactivated by norepinephrine reuptake in the frontal cortex


Question 18.
-Lacks dopamine transporters


Question 19.
-Increases dopamine neurotransmission in this part of the brain

,Question 20.
**FDA Approved for Pediatrics in tx Obsessive-compulsive disorder (OCD) (ages 10 and
older)


Question 21.
*Off-Label for Pediatric Use: Depression, Severe and treatment-resistant, depression,
Cataplexy syndrome, Anxiety, Insomnia,


Question 22.
Neuropathic pain/chronic pain


Question 23.
-Full therapeutic benefits may take 2-8 weeks


Question 24.
-Dosing: in Peds/Adolescents/Adults:


Question 25.
100-250mg/day


Question 26.
Cyamemazine (Tercian)

Correct Answer: Treatment for depression.


Question 27.
-Known as cyamepromazine


Question 28.
-Typical antipsychotic drug of the phenothiazine class.


Question 29.
-Treatment for schizophrenia


Question 30.
and psychosis-associated


Question 31.
anxiety

, Question 32.
-Behaves like an atypical antipsychotic, due to its


Question 33.
potent anxiolytic effects (5-HT2C) and lack of extrapyramidal side effects (5- HT2A).


Question 34.
-Conventional antipsychotic (neuroleptic, phenothiazine, dopamine 2 antagonist,
serotonin dopamine antagonist)


Question 35.
-Commonly Prescribed for (not FDA approved):


Question 36.
-Schizophrenia


Question 37.
-Anxiety associated with psychosis (short-term)


Question 38.
-Anxiety associated with nonpsychotic disorders, including mood disorders and
personality disorders (short-term)


Question 39.
-Severe depression


Question 40.
-Bipolar disorder


Question 41.
-Other psychotic disorders


Question 42.
-Acute agitation/aggression (injection)


Question 43.
-Benzodiazepine withdrawal

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