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NR546 Actual Final Exam 2024 Prediction
questions (All correct answers, Already graded A)
Prefrontal /aCortex /aSymptoms /aof /aMDD /a- /aCorrect /a /aAnswer /a- /aConcentration
Mental /aFatigue
Mood
PFC /a& /aAmygdala /aSymptoms /aof /aMDD /a- /aCorrect /a /aAnswer /a- /aGuilt
Suicidality
Worthlessness
Striatum /aSymptoms /aof /aMDD /a- /aCorrect /a /aAnswer /a- /aPhysical /afatigue
Nucleus /aAccumbens /aSymptoms /aof /aMDD /a- /aCorrect /a /aAnswer /a- /aPleasure /ainterests
Hypothalamus /aSymptoms /aof /aMDD /a- /aCorrect /a /aAnswer /a- /aSleep
Appetite
Thalamus /a& /aHypothalamus /aSymptoms /aof /aMania /a- /aCorrect /a /aAnswer /a- /aDecreased
/asleep/arousal
Striatum /aSymptoms /aof /aMania /a- /aCorrect /a /aAnswer /a- /aMotor/agitation
Prefrontal /acortex /a(PFC) /aSymptoms /aof /aMania /a- /aCorrect /a /aAnswer /a- /aRisk-taking
Talkative/pressured /aspeech
Nucleus /aAccumbens /a& /aPFC /aSymptoms /aof /aMania /a- /aCorrect /a /aAnswer /a- /aRacing
/athoughts, /agrandiosity
PFC /a& /aAmygdala /aSymptoms /aof /aMania /a- /aCorrect /a /aAnswer /a- /aMood
Medication /aManagement /a- /aCorrect /a /aAnswer /a- /aSSRI-Selective /aSerotonin /aReuptake
/aInhibitors
*Inhibit /a5 /aHT /areuptake
SNRI-Serotonin /aNorepinephrine /aReuptake /aInhibitors /a
*inhibit /a5-HT /areuptake
*inhibit /aNE /areuptake /a(increase /aenergy, /afocus)
*increase /aDA /ain /aprefrontal /acortex /a(increase /acognition)
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NDRI-Norepinephrine /aDopamine /aReuptake /ainhibitors
*inhibit /aDA /areuptake /a(increase /aalertness, /amotivation)
*inhibit /aNE /areuptake /a(increase /aenergy)
SARI-Serotonin /aAntagonist /aReuptake /aInhibitors
Selective /aSerotonin /aReuptake /aInhibitors /a(SSRIs): /aMost /aadverse /aeffects /awill
/asubside /aafter /a4-5 /adays /aonce /athe /abody /aadjusts /ato /aincreased /aserotonin /alevels. /a-
/aCorrect /a /aAnswer /a- /adiarrhea
headache
weight /again
sexual /aside /aeffects
Serotonin /aNorepinephrine /aReuptake /aInhibitors /a(SNRIs): /aMedications /ashould /anot /abe
/aabruptly /astopped /ato /aavoid /adiscontinuation /asymptoms. /aNE /aeffects /aof /athe
/amedication /amay /aincrease /aanxiety /ain /asome /aclients. /aReport /aworsening /aanxiety /ato
/athe /aprovider. /a- /aCorrect /a /aAnswer /a- /aelevated /ablood /apressure
anxiety
insomnia
constipation
Norepinephrine /aDopamine /aReuptake /aInhibitors /a(NDRI): /aTake /amedication /ain /athe
/amorning. /aStop /ataking /amedication /aif /aseizures /aoccur. /aStop /ataking /amedication /aif
/aanxiety /ais /anoted. /a- /aCorrect /a /aAnswer /a- /aagitation
headache
dry /amouth
constipation
weight /aloss
escitalopram /a(Lexapro) /aSSRI /a- /aCorrect /a /aAnswer /a- /ano /aknown /adrug /ainteractions
best /atolerated /aSSRI
27-32 /ahour /ahalf-life /agood /afor /aforgetful /aprone /aclients
least /aCYP /areactions
Substrate /afor /a3A4
citalopram /a(Celexa) /aSSRI /a- /aCorrect /a /aAnswer /a- /amild /aantihistamine /aeffects; /aHalf-
Life: /a23-45 /ahours
Weak /aInhibitor /aof /a2D6
fluoxetine /a(Prozac) /aSSRI /a- /aCorrect /a /aAnswer /a- /alongest /ahalf-life
Use /acaution /ain /apatients /awith /acomorbid /aanxiety /adue /ato /arisk /afor /aactivation /aand
/apanic /aattacks
Half-Life: /a2-3 /adays /aparent, /a2 /aweek /ametabolite
Inhibits /a2D6 /aand /a3A4
paroxetine /a(Paxil) /aSSRI /a- /aCorrect /a /aAnswer /a- /aalso /atreats /asocial /aanxiety /aand
/ainsomnia
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associated /awith /aweight /again
will /aexperience /awithdrawal /awith /amissed /adose /aor /aabrupt /astop
Half-Life: /a24 /ahours
Inhibits /a2D6
fluvoxamine /a(Luvox) /aSSRI /a- /aCorrect /a /aAnswer /a- /atreats /aanxious /adepression
/asmokers /arequire /aan /aincreased /adose
Half-Life: /a9-28 /ahours
Inhibits /a3A4, /a2C9, /a1A2
sertraline /a(Zoloft) /aSSRI /a- /aCorrect /a /aAnswer /a- /aalso /atreats /asocial /aanxiety /aand
/ahypersomnolence
Half-Life: /a22-36 /ahour /aparent; /a62-104 /ahour /ametabolite
Inhibits /a2D6 /aand /a3A4 /aweakly /aat /alow /adoses
venlafaxine /a(Effexor) /a- /aCorrect /a /aAnswer /a- /atreats /aboth /adepression /aand /aanxiety
/adisorders, /aensure /atrial /aof /ahigher /adose /abefore /aswitching /ato /aa /adifferent /amedication
Half-life: /aParent /adrug /a3-7 /ahour; /ametabolite /ahas /a9-13 /ahour
duloxetine /a(Cymbalta) /aSNRI /a- /aCorrect /a /aAnswer /a- /aeffective /afor /aatypical /apain /aat
/ahigher /adoses; /aappropriate /afor /aclients /awho /apresent /awith /asomatic /asymptoms /aof
/adepression; /aeffective /afor /aatypical /apain, /asuch /aas /afibromyalgia /aand /adiabetic
/aneuropathy
Half-Life: /a12 /ahours
Inhibitor /aof /a2D6
bupropion /a(Wellbutrin) /a- /aCorrect /a /aAnswer /a- /aNDRI /amay /aimprove /aenergy,
/aalertness, /aand /amotivation; /anot /afirst-line /atreatment /afor /aanxiety; /acontraindicated /ain
/aclients /awith /aa /ahistory /aof /aseizures
Avoid /ain /apatients /awith /acomorbid /aanxiety
Half-Life: /aParent /a10-14 /ahours; /aMetabolite /a20-27 /ahours
Inhibits /a2D6
Serotonin /aAntagonist /aand /aReuptake /aInhibitors /a(SARIs) /a- /aCorrect /a /aAnswer /a-
/aSARIs /apotently /ablock /a5-HT2A /aand /a5HT /a2C /areceptors, /awhich /aallow /amore /a5-HT
/ato /ainteract /aat /apostsynaptic /a5-HT1A /asites. /aSerotonin /ablockade /aand /areuptake
/ainhibition /ais /apresent /aat /ahigher /adoses.
Trazodone /a- /aCorrect /a /aAnswer /a- /aThe /amost /acommon /aSARI, /aalso /ablocks
/ahistaminergic /aand /aα-adrenergic /areceptors.
Half-Life: /a3-6 /ahours
Serotonin /aAntagonist /aand /aReuptake /aInhibitors /a(SARIs) /a- /aCorrect /a /aAnswer /a-
/aCommon /aAdverse /aEffects
· /asedation
· /adrowsiness
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· /ablurred /avision
· /aconstipation
· /adry /amouth
Serious /aAdverse /aEffect
priapism
Serotonin /anorepinephrine /areceptor /aagonist, /aalpha2 /areceptor /aagonist /a- /aCorrect /a
/aAnswer /a- /aMirtazapine
Serotonin /amultimodal /a(SMM)/serotonin /apartial /aagonist /areuptake /ainhibitor /a(SPARI) /a-
/aCorrect /a /aAnswer /a- /aVilazodone /a(Viibryd)
· /aInhibits /aserotonin /areuptake /awith /apartial /a5HT1A /aagonism
Appropriate /afor /adepression/comorbid /aanxiety, /aits /aaction /ais /asimilar /ato /aa
/acombination /aof /aSSRI /aand /abuspirone
Serotonin /amultimodal /a(SMM) /a- /aCorrect /a /aAnswer /a- /aVortioxetine /a(Trintellix)
· /aActs /aas /aSSRI /aplus /a5HT1A /apartial /aagonism
· /aImproves /adepression-related /acognition
Tricyclic /aantidepressants /a(TCAs) /a- /aCorrect /a /aAnswer /a- /aTricyclic /aantidepressants
/a(TCAs) /apossess /aboth /aSRI /aand /aNRI /aproperties, /abut /athey /aalso /ablock /aother
/areceptors, /aincluding /aα1-adrenergic, /ahistamine-1, /aand /amuscarinic /acholinergic
/areceptors. /aTCAs /aare /anot /aused /afirst-line /abecause /aof /athe /ahigh /aincidence /aof
/aadverse /aeffects /aand /athe /arisk /aof /apotential /aoverdose /aand /adeath /adue /ato /aoverdose
Tricyclic /aantidepressants /a(TCAs) /a- /aCorrect /a /aAnswer /a- /aDrugs:
· /aamitriptyline /a(Elavil)
· /adesipramine /a(Norpramin)
· /adoxepin /a(Sinequan)
· /aimipramine /a(Tofranil)
· /anortriptyline /a(Pamelor)
Tricyclic /aantidepressants /a(TCAs) /a- /aCorrect /a /aAnswer /a- /aCommon /aadverse /aeffects
/aof /aTCAs
Alpha-1 /aadrenergic /aeffects-Orthostatic /ahypotension
Histamine /aeffects-Sedation
Histamine /aeffects-Weight /again
Anticholinergic /aeffects-Blurred /avision
Anticholinergic /aeffects-Urinary /aretention
Anticholinergic /aeffects-Constipation
Anticholinergic /aeffects-Dry /amouth
MAOIs /a- /aCorrect /a /aAnswer /a- /aLast /achoice /amedication /aclass /afor /adepression /adue /ato
/athe /amany /apotential, /aserious /aside /aeffects. /aMAOIs /ahave /aspecific /adietary
/arestrictions /athat /awhen /aignored, /amay /abe /avery /auncomfortable /aor /avery /aserious /afor
/aclients.
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NR546 Actual Final Exam 2024 Prediction
questions (All correct answers, Already graded A)
Prefrontal /aCortex /aSymptoms /aof /aMDD /a- /aCorrect /a /aAnswer /a- /aConcentration
Mental /aFatigue
Mood
PFC /a& /aAmygdala /aSymptoms /aof /aMDD /a- /aCorrect /a /aAnswer /a- /aGuilt
Suicidality
Worthlessness
Striatum /aSymptoms /aof /aMDD /a- /aCorrect /a /aAnswer /a- /aPhysical /afatigue
Nucleus /aAccumbens /aSymptoms /aof /aMDD /a- /aCorrect /a /aAnswer /a- /aPleasure /ainterests
Hypothalamus /aSymptoms /aof /aMDD /a- /aCorrect /a /aAnswer /a- /aSleep
Appetite
Thalamus /a& /aHypothalamus /aSymptoms /aof /aMania /a- /aCorrect /a /aAnswer /a- /aDecreased
/asleep/arousal
Striatum /aSymptoms /aof /aMania /a- /aCorrect /a /aAnswer /a- /aMotor/agitation
Prefrontal /acortex /a(PFC) /aSymptoms /aof /aMania /a- /aCorrect /a /aAnswer /a- /aRisk-taking
Talkative/pressured /aspeech
Nucleus /aAccumbens /a& /aPFC /aSymptoms /aof /aMania /a- /aCorrect /a /aAnswer /a- /aRacing
/athoughts, /agrandiosity
PFC /a& /aAmygdala /aSymptoms /aof /aMania /a- /aCorrect /a /aAnswer /a- /aMood
Medication /aManagement /a- /aCorrect /a /aAnswer /a- /aSSRI-Selective /aSerotonin /aReuptake
/aInhibitors
*Inhibit /a5 /aHT /areuptake
SNRI-Serotonin /aNorepinephrine /aReuptake /aInhibitors /a
*inhibit /a5-HT /areuptake
*inhibit /aNE /areuptake /a(increase /aenergy, /afocus)
*increase /aDA /ain /aprefrontal /acortex /a(increase /acognition)
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NDRI-Norepinephrine /aDopamine /aReuptake /ainhibitors
*inhibit /aDA /areuptake /a(increase /aalertness, /amotivation)
*inhibit /aNE /areuptake /a(increase /aenergy)
SARI-Serotonin /aAntagonist /aReuptake /aInhibitors
Selective /aSerotonin /aReuptake /aInhibitors /a(SSRIs): /aMost /aadverse /aeffects /awill
/asubside /aafter /a4-5 /adays /aonce /athe /abody /aadjusts /ato /aincreased /aserotonin /alevels. /a-
/aCorrect /a /aAnswer /a- /adiarrhea
headache
weight /again
sexual /aside /aeffects
Serotonin /aNorepinephrine /aReuptake /aInhibitors /a(SNRIs): /aMedications /ashould /anot /abe
/aabruptly /astopped /ato /aavoid /adiscontinuation /asymptoms. /aNE /aeffects /aof /athe
/amedication /amay /aincrease /aanxiety /ain /asome /aclients. /aReport /aworsening /aanxiety /ato
/athe /aprovider. /a- /aCorrect /a /aAnswer /a- /aelevated /ablood /apressure
anxiety
insomnia
constipation
Norepinephrine /aDopamine /aReuptake /aInhibitors /a(NDRI): /aTake /amedication /ain /athe
/amorning. /aStop /ataking /amedication /aif /aseizures /aoccur. /aStop /ataking /amedication /aif
/aanxiety /ais /anoted. /a- /aCorrect /a /aAnswer /a- /aagitation
headache
dry /amouth
constipation
weight /aloss
escitalopram /a(Lexapro) /aSSRI /a- /aCorrect /a /aAnswer /a- /ano /aknown /adrug /ainteractions
best /atolerated /aSSRI
27-32 /ahour /ahalf-life /agood /afor /aforgetful /aprone /aclients
least /aCYP /areactions
Substrate /afor /a3A4
citalopram /a(Celexa) /aSSRI /a- /aCorrect /a /aAnswer /a- /amild /aantihistamine /aeffects; /aHalf-
Life: /a23-45 /ahours
Weak /aInhibitor /aof /a2D6
fluoxetine /a(Prozac) /aSSRI /a- /aCorrect /a /aAnswer /a- /alongest /ahalf-life
Use /acaution /ain /apatients /awith /acomorbid /aanxiety /adue /ato /arisk /afor /aactivation /aand
/apanic /aattacks
Half-Life: /a2-3 /adays /aparent, /a2 /aweek /ametabolite
Inhibits /a2D6 /aand /a3A4
paroxetine /a(Paxil) /aSSRI /a- /aCorrect /a /aAnswer /a- /aalso /atreats /asocial /aanxiety /aand
/ainsomnia
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associated /awith /aweight /again
will /aexperience /awithdrawal /awith /amissed /adose /aor /aabrupt /astop
Half-Life: /a24 /ahours
Inhibits /a2D6
fluvoxamine /a(Luvox) /aSSRI /a- /aCorrect /a /aAnswer /a- /atreats /aanxious /adepression
/asmokers /arequire /aan /aincreased /adose
Half-Life: /a9-28 /ahours
Inhibits /a3A4, /a2C9, /a1A2
sertraline /a(Zoloft) /aSSRI /a- /aCorrect /a /aAnswer /a- /aalso /atreats /asocial /aanxiety /aand
/ahypersomnolence
Half-Life: /a22-36 /ahour /aparent; /a62-104 /ahour /ametabolite
Inhibits /a2D6 /aand /a3A4 /aweakly /aat /alow /adoses
venlafaxine /a(Effexor) /a- /aCorrect /a /aAnswer /a- /atreats /aboth /adepression /aand /aanxiety
/adisorders, /aensure /atrial /aof /ahigher /adose /abefore /aswitching /ato /aa /adifferent /amedication
Half-life: /aParent /adrug /a3-7 /ahour; /ametabolite /ahas /a9-13 /ahour
duloxetine /a(Cymbalta) /aSNRI /a- /aCorrect /a /aAnswer /a- /aeffective /afor /aatypical /apain /aat
/ahigher /adoses; /aappropriate /afor /aclients /awho /apresent /awith /asomatic /asymptoms /aof
/adepression; /aeffective /afor /aatypical /apain, /asuch /aas /afibromyalgia /aand /adiabetic
/aneuropathy
Half-Life: /a12 /ahours
Inhibitor /aof /a2D6
bupropion /a(Wellbutrin) /a- /aCorrect /a /aAnswer /a- /aNDRI /amay /aimprove /aenergy,
/aalertness, /aand /amotivation; /anot /afirst-line /atreatment /afor /aanxiety; /acontraindicated /ain
/aclients /awith /aa /ahistory /aof /aseizures
Avoid /ain /apatients /awith /acomorbid /aanxiety
Half-Life: /aParent /a10-14 /ahours; /aMetabolite /a20-27 /ahours
Inhibits /a2D6
Serotonin /aAntagonist /aand /aReuptake /aInhibitors /a(SARIs) /a- /aCorrect /a /aAnswer /a-
/aSARIs /apotently /ablock /a5-HT2A /aand /a5HT /a2C /areceptors, /awhich /aallow /amore /a5-HT
/ato /ainteract /aat /apostsynaptic /a5-HT1A /asites. /aSerotonin /ablockade /aand /areuptake
/ainhibition /ais /apresent /aat /ahigher /adoses.
Trazodone /a- /aCorrect /a /aAnswer /a- /aThe /amost /acommon /aSARI, /aalso /ablocks
/ahistaminergic /aand /aα-adrenergic /areceptors.
Half-Life: /a3-6 /ahours
Serotonin /aAntagonist /aand /aReuptake /aInhibitors /a(SARIs) /a- /aCorrect /a /aAnswer /a-
/aCommon /aAdverse /aEffects
· /asedation
· /adrowsiness
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· /ablurred /avision
· /aconstipation
· /adry /amouth
Serious /aAdverse /aEffect
priapism
Serotonin /anorepinephrine /areceptor /aagonist, /aalpha2 /areceptor /aagonist /a- /aCorrect /a
/aAnswer /a- /aMirtazapine
Serotonin /amultimodal /a(SMM)/serotonin /apartial /aagonist /areuptake /ainhibitor /a(SPARI) /a-
/aCorrect /a /aAnswer /a- /aVilazodone /a(Viibryd)
· /aInhibits /aserotonin /areuptake /awith /apartial /a5HT1A /aagonism
Appropriate /afor /adepression/comorbid /aanxiety, /aits /aaction /ais /asimilar /ato /aa
/acombination /aof /aSSRI /aand /abuspirone
Serotonin /amultimodal /a(SMM) /a- /aCorrect /a /aAnswer /a- /aVortioxetine /a(Trintellix)
· /aActs /aas /aSSRI /aplus /a5HT1A /apartial /aagonism
· /aImproves /adepression-related /acognition
Tricyclic /aantidepressants /a(TCAs) /a- /aCorrect /a /aAnswer /a- /aTricyclic /aantidepressants
/a(TCAs) /apossess /aboth /aSRI /aand /aNRI /aproperties, /abut /athey /aalso /ablock /aother
/areceptors, /aincluding /aα1-adrenergic, /ahistamine-1, /aand /amuscarinic /acholinergic
/areceptors. /aTCAs /aare /anot /aused /afirst-line /abecause /aof /athe /ahigh /aincidence /aof
/aadverse /aeffects /aand /athe /arisk /aof /apotential /aoverdose /aand /adeath /adue /ato /aoverdose
Tricyclic /aantidepressants /a(TCAs) /a- /aCorrect /a /aAnswer /a- /aDrugs:
· /aamitriptyline /a(Elavil)
· /adesipramine /a(Norpramin)
· /adoxepin /a(Sinequan)
· /aimipramine /a(Tofranil)
· /anortriptyline /a(Pamelor)
Tricyclic /aantidepressants /a(TCAs) /a- /aCorrect /a /aAnswer /a- /aCommon /aadverse /aeffects
/aof /aTCAs
Alpha-1 /aadrenergic /aeffects-Orthostatic /ahypotension
Histamine /aeffects-Sedation
Histamine /aeffects-Weight /again
Anticholinergic /aeffects-Blurred /avision
Anticholinergic /aeffects-Urinary /aretention
Anticholinergic /aeffects-Constipation
Anticholinergic /aeffects-Dry /amouth
MAOIs /a- /aCorrect /a /aAnswer /a- /aLast /achoice /amedication /aclass /afor /adepression /adue /ato
/athe /amany /apotential, /aserious /aside /aeffects. /aMAOIs /ahave /aspecific /adietary
/arestrictions /athat /awhen /aignored, /amay /abe /avery /auncomfortable /aor /avery /aserious /afor
/aclients.
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