Test Bank for Clinical Hematology and Fundamentals of Hemostasis, 6th Edition
by Harmening
Chapter 1: Morphology and Maturation of Human Blood Cells: Hematopoiesis
1. What is meant by medullary hematopoiesis?
A) Hematopoiesis in the spleen
B) Hematopoiesis in marrow
C) Hematopoiesis in liver
D) Hematopoiesis in thymus
Correct Answer: B
L.O.: 1-13
Taxonomy: 1
2. What percentage of erythrocytes is functional in peripheral blood after release from the
bone marrow?
A) 70%
B) 50%
C) 80%
D) 100%
Correct Answer: D
L.O.: 1-1, 1-13
Taxonomy: 1
3. The hematopoietic system consists of all the following except:
A) Thymus
B) Bone marrow
C) Kidneys
D) Spleen
Correct Answer: C
L.O.: 1-13
Taxonomy: 1
4. What is the sequence of maturity for the erythrocyte?
A) Pronormoblast, basophilic normoblast, polychromatophilic normoblast,
orthochromatic normoblast, reticulocyte, erythrocyte
B) Basophilic normoblast, pronormoblast, orthochromatic normoblast, reticulocyte,
erythrocyte, polychromatophilic normoblast
C) Orthochromatic normoblast, pronormoblast, reticulocyte, erythrocyte, basophilic
normoblast, polychromatophilic normoblast
D) Polychromatophilic normoblast, orthochromatic normoblast, pronormoblast,
erythrocyte, reticulocyte, basophilic normoblast
Correct Answer: A
L.O.: 1-8
Taxonomy: 3
,Test Bank for Clinical Hematology and Fundamentals of Hemostasis, 6th Edition
by Harmening
Chapter 1: Morphology of Human Blood Cells: Hematopoiesis
5. By increasing hematopoiesis, the hematopoietic system can respond to stimuli such as:
A) Homeostasis
B) Hypoxia
C) Clotting
D) Hyperplasia
Correct Answer: B
L.O.: 1-13
Taxonomy: 3
6. In which immature erythroid cell are nucleoli most visible?
A) Basophilic normoblast
B) Orthochromatic normoblast
C) Pronormoblast
D) Polychromatic normoblast
Correct Answer: C
L.O.: 1-8
Taxonomy: 1
7. What is the average diameter of a normal erythrocyte?
A) 3–5 µm
B) 2–4 µm
C) 8–10 µm
D) 7–8 µm
Correct Answer: D
L.O.: 1-2
Taxonomy: 1
8. Which of the following does not characterize the maturation of the granulocytic series?
A) Decrease in nuclear volume
B) Appearance and disappearance of primary granules
C) Nuclear chromatin clumping
D) Cytoplasmic color change from pink to blue
Correct Answer: D
L.O.: 1-10
Taxonomy: 2
Page 2
,Test Bank for Clinical Hematology and Fundamentals of Hemostasis, 6th Edition
by Harmening
Chapter 1: Morphology of Human Blood Cells: Hematopoiesis
9. The sequence of maturity of the neutrophil is:
A) Myeloblast, promyelocyte, myelocyte, metamyelocyte, band neutrophil, segmented
neutrophil
B) Myeloblast, promyelocyte, metamyelocyte, myelocyte, band neutrophil, segmented
neutrophil
C) Myeloblast, promyelocyte, band neutrophil, metamyelocyte, myelocyte, segmented
neutrophil
D) Myeloblast, myelocyte, promyelocyte, metamyelocyte, band neutrophil, segmented
neutrophil
Correct Answer: A
L.O.: 1-9
Taxonomy: 3
10. The stage in granulocyte maturation where the nucleus appears kidney-shaped is evident
in what cell?
A) Promyelocyte
B) Band neutrophil
C) Metamyelocyte
D) Myelocyte
Correct Answer: C
L.O.: 1-10
Taxonomy: 1
11. What percentage of band neutrophils is present in normal adult peripheral blood?
A) 1%–4%
B) 2%–6%
C) 10%–12%
D) 4%–8%
Correct Answer: B
L.O.: 1-1, 1-2
Taxonomy: 1
12. The first sign of neutrophilic differentiation and appearance of secondary granules is
evident in what cell type?
A) Promyelocyte
B) Myelocyte
C) Segmented neutrophil
D) Metamyelocyte
Correct Answer: B
L.O.: 1-10
, Test Bank for Clinical Hematology and Fundamentals of Hemostasis, 6th Edition
by Harmening
Chapter 1: Morphology of Human Blood Cells: Hematopoiesis
13. Which cell in the granulocytic series is present in the greatest percentages in normal bone
marrow?
A) Band neutrophil
B) Promyelocyte
C) Metamyelocyte
D) Myelocyte
Correct Answer: A
L.O.: 1-9
Taxonomy: 1
14. Which characteristic is used to differentiate a large lymphocyte from a monocyte?
A) Distinct bluish-red granules
B) Blue-gray cytoplasm
C) Round nucleus
D) Indented cytoplasm from surrounding RBCs
Correct Answer: D
L.O.: 1-7
Taxonomy: 2
15. What color do the eosinophilic granules retain with the Wright's stain?
A) Bluish-purple
B) Reddish-orange
C) Clear
D) Purple-black
Correct Answer: B
L.O.: 1-2, 1-4
Taxonomy: 1
16. What stages do both basophils and eosinophils pass through in their sequence of
maturity?
A) Promyelocyte, myelocyte, band cell, segmented cell
B) Myeloblast, promyelocyte, myelocyte, band cell, segmented cell
C) Myelocyte, metamyelocyte, band cell, segmented cell
D) Band cell, myelocyte, metamyelocyte, segmented cell
Correct Answer: C
L.O.: 1-9
Taxonomy: 2
Page 4
by Harmening
Chapter 1: Morphology and Maturation of Human Blood Cells: Hematopoiesis
1. What is meant by medullary hematopoiesis?
A) Hematopoiesis in the spleen
B) Hematopoiesis in marrow
C) Hematopoiesis in liver
D) Hematopoiesis in thymus
Correct Answer: B
L.O.: 1-13
Taxonomy: 1
2. What percentage of erythrocytes is functional in peripheral blood after release from the
bone marrow?
A) 70%
B) 50%
C) 80%
D) 100%
Correct Answer: D
L.O.: 1-1, 1-13
Taxonomy: 1
3. The hematopoietic system consists of all the following except:
A) Thymus
B) Bone marrow
C) Kidneys
D) Spleen
Correct Answer: C
L.O.: 1-13
Taxonomy: 1
4. What is the sequence of maturity for the erythrocyte?
A) Pronormoblast, basophilic normoblast, polychromatophilic normoblast,
orthochromatic normoblast, reticulocyte, erythrocyte
B) Basophilic normoblast, pronormoblast, orthochromatic normoblast, reticulocyte,
erythrocyte, polychromatophilic normoblast
C) Orthochromatic normoblast, pronormoblast, reticulocyte, erythrocyte, basophilic
normoblast, polychromatophilic normoblast
D) Polychromatophilic normoblast, orthochromatic normoblast, pronormoblast,
erythrocyte, reticulocyte, basophilic normoblast
Correct Answer: A
L.O.: 1-8
Taxonomy: 3
,Test Bank for Clinical Hematology and Fundamentals of Hemostasis, 6th Edition
by Harmening
Chapter 1: Morphology of Human Blood Cells: Hematopoiesis
5. By increasing hematopoiesis, the hematopoietic system can respond to stimuli such as:
A) Homeostasis
B) Hypoxia
C) Clotting
D) Hyperplasia
Correct Answer: B
L.O.: 1-13
Taxonomy: 3
6. In which immature erythroid cell are nucleoli most visible?
A) Basophilic normoblast
B) Orthochromatic normoblast
C) Pronormoblast
D) Polychromatic normoblast
Correct Answer: C
L.O.: 1-8
Taxonomy: 1
7. What is the average diameter of a normal erythrocyte?
A) 3–5 µm
B) 2–4 µm
C) 8–10 µm
D) 7–8 µm
Correct Answer: D
L.O.: 1-2
Taxonomy: 1
8. Which of the following does not characterize the maturation of the granulocytic series?
A) Decrease in nuclear volume
B) Appearance and disappearance of primary granules
C) Nuclear chromatin clumping
D) Cytoplasmic color change from pink to blue
Correct Answer: D
L.O.: 1-10
Taxonomy: 2
Page 2
,Test Bank for Clinical Hematology and Fundamentals of Hemostasis, 6th Edition
by Harmening
Chapter 1: Morphology of Human Blood Cells: Hematopoiesis
9. The sequence of maturity of the neutrophil is:
A) Myeloblast, promyelocyte, myelocyte, metamyelocyte, band neutrophil, segmented
neutrophil
B) Myeloblast, promyelocyte, metamyelocyte, myelocyte, band neutrophil, segmented
neutrophil
C) Myeloblast, promyelocyte, band neutrophil, metamyelocyte, myelocyte, segmented
neutrophil
D) Myeloblast, myelocyte, promyelocyte, metamyelocyte, band neutrophil, segmented
neutrophil
Correct Answer: A
L.O.: 1-9
Taxonomy: 3
10. The stage in granulocyte maturation where the nucleus appears kidney-shaped is evident
in what cell?
A) Promyelocyte
B) Band neutrophil
C) Metamyelocyte
D) Myelocyte
Correct Answer: C
L.O.: 1-10
Taxonomy: 1
11. What percentage of band neutrophils is present in normal adult peripheral blood?
A) 1%–4%
B) 2%–6%
C) 10%–12%
D) 4%–8%
Correct Answer: B
L.O.: 1-1, 1-2
Taxonomy: 1
12. The first sign of neutrophilic differentiation and appearance of secondary granules is
evident in what cell type?
A) Promyelocyte
B) Myelocyte
C) Segmented neutrophil
D) Metamyelocyte
Correct Answer: B
L.O.: 1-10
, Test Bank for Clinical Hematology and Fundamentals of Hemostasis, 6th Edition
by Harmening
Chapter 1: Morphology of Human Blood Cells: Hematopoiesis
13. Which cell in the granulocytic series is present in the greatest percentages in normal bone
marrow?
A) Band neutrophil
B) Promyelocyte
C) Metamyelocyte
D) Myelocyte
Correct Answer: A
L.O.: 1-9
Taxonomy: 1
14. Which characteristic is used to differentiate a large lymphocyte from a monocyte?
A) Distinct bluish-red granules
B) Blue-gray cytoplasm
C) Round nucleus
D) Indented cytoplasm from surrounding RBCs
Correct Answer: D
L.O.: 1-7
Taxonomy: 2
15. What color do the eosinophilic granules retain with the Wright's stain?
A) Bluish-purple
B) Reddish-orange
C) Clear
D) Purple-black
Correct Answer: B
L.O.: 1-2, 1-4
Taxonomy: 1
16. What stages do both basophils and eosinophils pass through in their sequence of
maturity?
A) Promyelocyte, myelocyte, band cell, segmented cell
B) Myeloblast, promyelocyte, myelocyte, band cell, segmented cell
C) Myelocyte, metamyelocyte, band cell, segmented cell
D) Band cell, myelocyte, metamyelocyte, segmented cell
Correct Answer: C
L.O.: 1-9
Taxonomy: 2
Page 4
