WGU D116 OA
Study online at https://quizlet.com/_ioo5ua
1. 1st line weight loss: Diet and exercise
2. 1st line Panic attack medication: SSRIs (Selective Serotonin Reuptake Inhibitors): Often first choice
for many anxiety disorders, increasing serotonin.
Examples: Sertraline (Zoloft), Escitalopram (Lexapro), Fluoxetine (Prozac).
SNRIs (Serotonin-Norepinephrine Reuptake Inhibitors): Also common first-line, affecting serotonin and norepineph-
rine.
Examples: Venlafaxine (Effexor XR), Duloxetine (Cymbalta)
3. Zidovudine side effect: aplastic anemia
Blood and Bone Marrow Problems: Symptoms such as unusual bleeding or bruising, persistent fever or chills, sore
throat, or pale skin may indicate low red or white blood cell counts (anemia or neutropenia). Regular blood tests are
recommended to monitor for these issues.
Muscle Damage (Myopathy): Unexplained muscle pain, tenderness, or weakness, especially with long-term use,
should be reported to a doctor.
Lactic Acidosis and Liver Problems: This is a rare but serious condition involving a buildup of lactic acid in the blood,
which can be fatal. Symptoms include unusual muscle pain, trouble breathing, stomach pain, nausea, vomiting,
dizziness, or yellowing of the skin or eyes (jaundice).
Fat Redistribution (Lipoatrophy): Zidovudine use may lead to a loss of subcutaneous fat in the face, arms, legs, or
buttocks, and/or an increase of fat in other areas like the upper back or stomach.
Immune Reconstitution Syndrome: As the immune system gets stronger after starting treatment, it may begin fighting
existing but previously unnoticed infections, causing new symptoms.
4. Sildenafil contraindicated with which meds: Nitrates, such as nitroglycerin (Nitrostat) and
isosorbide mononitrate (Monoket)
Soluble guanylate cyclase (sGC) stimulators, such as riociguat (Adempas)
Alpha blockers, such as tamsulosin (Flomax), alfuzosin (Uroxatral), and doxazosin (Cardura)
Blood pressure medications, such as lisinopril (Zestril Qbrelis), losartan (Cozaar, Arbli), and amlodipine (Norvasc)
Alcohol
Ritonavir (Norvir)
Paxlovid (nirmatrelvir / ritonavir)
Clarithromycin
, WGU D116 OA
Study online at https://quizlet.com/_ioo5ua
Ketoconazole
Rifampin (Rifadin)
Carbamazepine (Tegretol, Carbatrol)
St. John's wort
Grapefruit juice
5. Atropine MOA for a patient being treated for asystole: Atropine, a cholinergic blocking
drug, competes with acetyl-choline for cholinergic receptor sites on the SA and AV nodes.
By blocking acetylcholine, atropine speeds up the heart rate. It blocks vagal (parasympathetic) action on the heart's
sinoatatrial (SA) and atrioventricular (AV) nodes, increasing the heart rate and conduction velocity. By blocking ACh,
atropine removes the "brake," letting the SA node fire faster and the AV node conduct signals quicker, resulting in a
faster heart rate (tachycardia) and better electrical flow.
6. Hydralazine increases blood flow in: arterioles (arteries) vasodilation
7. Child 8 years old with a UTI has been unsuccessfully treated with
azithromycin, what antibiotic should be administered next?
a)vancomycin
b)penicillin g
c)clindamycin
d) ?: Trimethoprim/sulfamethoxazole
8. Urine and bile are excreted through which pharmacological process: Elimination
9. Care Coordination and Transition Management (CCTM): American Academy of Ambu-
latory Care Nursing (AAACN)
10. Eye drops for allergy: Ketotifen
11. Myxedema coma, why use liothyronine over levothyroxine: Impaired Conversion:
Severe illness (like myxedema coma) slows down the conversion of T4 (storage hormone) to T3 (active hormone), so
giving T3 directly bypasses this bottleneck.
Quicker Action: T3 is the active hormone, providing a more immediate biological effect than T4, which needs
conversion first.
Life-Threatening Urgency: Myxedema coma requires rapid restoration of thyroid function, and T3's speed helps
address the critical metabolic slowdown quickly. Combination Therapy: Many guidelines suggest starting with
intravenous levothyroxine (T4) and adding liothyronine (T3) in lower doses (e.g., 5-20 mcg loading dose) to speed
up recovery
12. Contraindication for bowel obstruction: Senna
Study online at https://quizlet.com/_ioo5ua
1. 1st line weight loss: Diet and exercise
2. 1st line Panic attack medication: SSRIs (Selective Serotonin Reuptake Inhibitors): Often first choice
for many anxiety disorders, increasing serotonin.
Examples: Sertraline (Zoloft), Escitalopram (Lexapro), Fluoxetine (Prozac).
SNRIs (Serotonin-Norepinephrine Reuptake Inhibitors): Also common first-line, affecting serotonin and norepineph-
rine.
Examples: Venlafaxine (Effexor XR), Duloxetine (Cymbalta)
3. Zidovudine side effect: aplastic anemia
Blood and Bone Marrow Problems: Symptoms such as unusual bleeding or bruising, persistent fever or chills, sore
throat, or pale skin may indicate low red or white blood cell counts (anemia or neutropenia). Regular blood tests are
recommended to monitor for these issues.
Muscle Damage (Myopathy): Unexplained muscle pain, tenderness, or weakness, especially with long-term use,
should be reported to a doctor.
Lactic Acidosis and Liver Problems: This is a rare but serious condition involving a buildup of lactic acid in the blood,
which can be fatal. Symptoms include unusual muscle pain, trouble breathing, stomach pain, nausea, vomiting,
dizziness, or yellowing of the skin or eyes (jaundice).
Fat Redistribution (Lipoatrophy): Zidovudine use may lead to a loss of subcutaneous fat in the face, arms, legs, or
buttocks, and/or an increase of fat in other areas like the upper back or stomach.
Immune Reconstitution Syndrome: As the immune system gets stronger after starting treatment, it may begin fighting
existing but previously unnoticed infections, causing new symptoms.
4. Sildenafil contraindicated with which meds: Nitrates, such as nitroglycerin (Nitrostat) and
isosorbide mononitrate (Monoket)
Soluble guanylate cyclase (sGC) stimulators, such as riociguat (Adempas)
Alpha blockers, such as tamsulosin (Flomax), alfuzosin (Uroxatral), and doxazosin (Cardura)
Blood pressure medications, such as lisinopril (Zestril Qbrelis), losartan (Cozaar, Arbli), and amlodipine (Norvasc)
Alcohol
Ritonavir (Norvir)
Paxlovid (nirmatrelvir / ritonavir)
Clarithromycin
, WGU D116 OA
Study online at https://quizlet.com/_ioo5ua
Ketoconazole
Rifampin (Rifadin)
Carbamazepine (Tegretol, Carbatrol)
St. John's wort
Grapefruit juice
5. Atropine MOA for a patient being treated for asystole: Atropine, a cholinergic blocking
drug, competes with acetyl-choline for cholinergic receptor sites on the SA and AV nodes.
By blocking acetylcholine, atropine speeds up the heart rate. It blocks vagal (parasympathetic) action on the heart's
sinoatatrial (SA) and atrioventricular (AV) nodes, increasing the heart rate and conduction velocity. By blocking ACh,
atropine removes the "brake," letting the SA node fire faster and the AV node conduct signals quicker, resulting in a
faster heart rate (tachycardia) and better electrical flow.
6. Hydralazine increases blood flow in: arterioles (arteries) vasodilation
7. Child 8 years old with a UTI has been unsuccessfully treated with
azithromycin, what antibiotic should be administered next?
a)vancomycin
b)penicillin g
c)clindamycin
d) ?: Trimethoprim/sulfamethoxazole
8. Urine and bile are excreted through which pharmacological process: Elimination
9. Care Coordination and Transition Management (CCTM): American Academy of Ambu-
latory Care Nursing (AAACN)
10. Eye drops for allergy: Ketotifen
11. Myxedema coma, why use liothyronine over levothyroxine: Impaired Conversion:
Severe illness (like myxedema coma) slows down the conversion of T4 (storage hormone) to T3 (active hormone), so
giving T3 directly bypasses this bottleneck.
Quicker Action: T3 is the active hormone, providing a more immediate biological effect than T4, which needs
conversion first.
Life-Threatening Urgency: Myxedema coma requires rapid restoration of thyroid function, and T3's speed helps
address the critical metabolic slowdown quickly. Combination Therapy: Many guidelines suggest starting with
intravenous levothyroxine (T4) and adding liothyronine (T3) in lower doses (e.g., 5-20 mcg loading dose) to speed
up recovery
12. Contraindication for bowel obstruction: Senna
